Research project

Structure, activity and membrane binding of retinol dehydrogenase 12 and its mutants

Project Description

The visual cycle takes place in both photoreceptors and the retinal pigment epithelium. It allows the regeneration of the visual pigment. Retinol dehydrogenase 12 (RDH12) is a membrane-associated enzyme playing an important role in the visual cycle. Moreover, several mutations of RDH12 lead to eye illnesses and the loss of vision. It is thus very important to characterize the structure, activity and membrane binding of RDH12 and its mutants in order to understand their involvement in the vision loss.

Research Field

- Ophthalmologie
- Visual system
- Enzymes and proteins

Research Supervisor

Christian Salesse

Research Environment

Research Centre of the CHU de Québec-Université Laval

Research Centre of the CHU de Québec-Université Laval is one of the largest research centres of Canada with 507 researchers and 927 graduate students. It includes seven research divisions and a large number of platforms and technical services. The CUO-Recherche includes all researchers working in the field of eyesight.

Web Site


Related Programs

Doctorate in Biochemistry

Program description

Financial aid available*

Financial aid related to research project

$18000 per year for 3 years.

Program-Specific Financial Aid

Graduate Studies Awards

Plan Steps Incentive
Progression studentship
7 x $500
Doctoral exam or seminar presentation
$750
Doctoral exam, seminar or conference
$1,000
Publication
$750
Communication
$1,000
Initial thesis submission
$1,000*
Total $8,500

*A $ 500 bonus will be added to the studentship for graduation if the initial deposit is made before the session that precedes the maximum qualifying session.

Université Laval: Student Financial Aid

Funding source Amount
Université Laval Doctoral Admission Scholarship  $2,000
Leadership and Sustainable Development Scholarships 
3 x $10,000
Mobility Grant for Out-of-Province Internships (in French)
$1,000
Graduate Scholarships from Granting Agencies   
$21,000 to $50,000$
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Supplemental Tuition Fee Exemption Scholarship Program: Entitles international students to pay Canadian student tuition fees, for overall savings of around $30,000.

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Doctorate in Cellular and Molecular Biology

Program description

Financial aid available*

Financial aid related to research project

$18000 per year for 3 years.

Program-Specific Financial Aid

Graduate Studies Awards

Plan Steps Incentive
Progression studentship (S-1 to S-8)
8 x $525
Progression studentship (S-9 to S-11) 3 x $200
Ph.D exam success
$800
Thesis deposit before the end of the 12th semester of full-time registration
$2,000
English or French as a Second Language training
$250
Total $7,850


Recruitment scholarships

Faculty of Medicine: Doctoral recruitment scholarships of up to $10,000.

Université Laval Research Fund for Arthritis and Rheumatic Diseases (FRAMR): Amounts up to $10,000.

Ven Murthy Scholarship: Two $25,000 recruitment scholarships in neuroscience for foreign students.

Université Laval: Student Financial Aid

Funding source Amount
Université Laval Doctoral Admission Scholarship  $2,000
Leadership and Sustainable Development Scholarships 
3 x $10,000
Mobility Grant for Out-of-Province Internships (in French)
$1,000
Graduate Scholarships from Granting Agencies   
$21,000 to $50,000$
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Supplemental Tuition Fee Exemption Scholarship Program: Entitles international students to pay Canadian student tuition fees, for overall savings of around $30,000.

* Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Master's in Biochemistry - with dissertation

Program description

Financial aid available*

Financial aid related to research project

$15000 per year for 2 years.

Program-Specific Financial Aid

Graduate Studies Awards

Plan Steps Incentive
Evaluated activity
$650
Achievement scholarship
$1,000
Total $1,650

Université Laval: Student Financial Aid

Sources de financement Montant
Leadership and Sustainable Development Scholarships 2 x $5,000
Mobility Grant for Out-of-Province Internships (in French)
$1,000
Graduate Scholarships from Granting Agencies
$14,100 to $21,000
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Master's Scholarships for International StudentsThese scholarships are available in a number of programs to students from Africa and Europe, excluding France. This scholarship of $7,000 per year is awarded based on university academic achievement * Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Master's in Cellular and Molecular Biology - with dissertation

Program description

Financial aid available*

Financial aid related to research project

$15000 per year for 2 years.

Program-Specific Financial Aid

Graduate Studies Awards

Plan Steps Incentive
Initial thesis submission before the end of the 6th semester of full-time registration
$1,000
English or French as a Second Language training
$250
Total $1,250

Faculty of Medicine Financial Assistance Fund for Academic Success: Two $5,000 merit awards.

Recruitment scholarships

Université Laval Research Fund for Arthritis and Rheumatic Diseases (FRAMR): Amounts up to $7,500.

Hydro-Québec Admission Scholarship: $5,000.

Faculty of Medicine Golf Tournament: Six $500 admission scholarships.

Université Laval: Student Financial Aid

Sources de financement Montant
Leadership and Sustainable Development Scholarships 2 x $5,000
Mobility Grant for Out-of-Province Internships (in French)
$1,000
Graduate Scholarships from Granting Agencies
$14,100 to $21,000
Online Directory of Graduate Scholarships (in French)
$500 to $50,000

Master's Scholarships for International StudentsThese scholarships are available in a number of programs to students from Africa and Europe, excluding France. This scholarship of $7,000 per year is awarded based on university academic achievement * Amounts shown represent maximum financial aid available. Certain conditions apply. Subject to change without prior notice. For further information, contact sponsoring organizations directly.

Desired Profile

- Biomedical Science
- Biochemistry
- Biology

Requirements and Conditions

-Highly motivated student
-Background in molecular biology would be an asset

Required Documentation

- Curriculum vitæ
- Student transcript

Find Out More

Christian Salesse
Professeur titulaire
Département d'ophtalmologie et oto-rhino-laryngologie - chirurgie cervico-faciale
christian.salesse@fmed.ulaval.ca