Denis Giguère

• Centre de recherche en infectiologie
• Centre de recherche sur les protéines PROTEO-ULaval

Financements des 2 dernières années

• Amélia Poulin, Maîtrise en chimie - avec mémoire
• Christina Leclerc, Maîtrise en chimie - avec mémoire
• Christina Leclerc, Doctorat en chimie
• Dylan Yorga, Stage postdoctoral en chimie
• Mathilde Grosset-Magagne, Doctorat en chimie
• Sam Bahadori, Doctorat en chimie

Encadrements des 5 dernières années

• Danny Lainé, Doctorat en chimie
• Jacob St-Gelais, Doctorat en chimie
• Jessica Berline Alcée, Maîtrise en chimie - avec mémoire
• Megan Bouchard, Maîtrise en chimie - avec mémoire
• Myriame Proulx, Maîtrise en chimie - avec mémoire
• Olivier Lessard, Maîtrise en chimie - avec mémoire
• Olivier Lessard, Doctorat en chimie
• Thomas Tremblay, Doctorat en chimie

Travaux de recherche des 5 dernières années

Chiral Copper(II) Complex‐Catalyzes Site‐Selective Monofunctionalization of Levoglucosan Analogs European Journal of Organic Chemistry, 2026. Christina Leclerc, Sam Bahadori, Dylan Yorga, Jérôme Désiré, Yves Blériot, Paul A. Johnson, Denis Giguère. DOI 10.1002/ejoc.70940

Correction to “Rapid and Accurate Determination of 226Ra from Drinking Water Using Macropa-Mediated Cloud Point Extraction Coupled with ICP-MS/MS” Analytical Chemistry, 2026. Jegan Govindaraj, Myriame Proulx, Amélia Poulin, Guillaume Blanchet-Chouinard, Steeve Roberge, Denis Giguère, Dominic Larivière. DOI 10.1021/acs.analchem.6c04397

Rapid and Accurate Determination of 226Ra from Drinking Water Using Macropa-Mediated Cloud Point Extraction Coupled with ICP-MS/MS Analytical Chemistry, 2026. Jegan Govindaraj, Myriame Proulx, Guillaume Blanchet-Chouinard, Steeve Roberge, Denis Giguère, Dominic Larivière. DOI 10.1021/acs.analchem.5c07724

Synthesis of Rare‐Bacterial Sugar Analogs: Thomosamine and Fluorinated Thomosamine European Journal of Organic Chemistry, 2025. Sam Bahadori, Mathilde Grosset‐Magagne, Denis Giguère. DOI 10.1002/ejoc.202500523

Synthesis and Conformational Analysis of Pyran Interhalide Analogues of Galactose, Mannose, Talose, and Glucose Chemistry – A European Journal, 2025. Olivier Lessard, Mathilde Grosset‐Magagne, Pierangelo Metrangolo, Denis Giguère. DOI 10.1002/chem.202501689

Catalyst-Controlled, Site-Selective Functionalization of Levoglucosan Analogues Mediated by Chiral Zinc Diamine Complexes The Journal of Organic Chemistry, 2025. Sam Bahadori, Christina Leclerc, Jacob St-Gelais, Guillaume Poulin, Denis Giguère. DOI 10.1021/acs.joc.4c02681

Convergent Synthesis of a Group B Streptococcus Type III Epitope Toward a Semisynthetic Carbohydrate-Based Vaccine The Journal of Organic Chemistry, 2024. Sam Bahadori, Marie-Jeanne Archambault, Mathew Sebastiao, Steve Bourgault, Denis Giguère. DOI 10.1021/acs.joc.4c01216

Synthesis and conformational analysis of pyran inter-halide analogues of ᴅ-talose Beilstein Journal of Organic Chemistry, 2024. Olivier Lessard, Mathilde Grosset-Magagne, Paul A Johnson, Denis Giguère. DOI 10.3762/bjoc.20.208

Synthesis and Conformational Analysis of Pyran Inter-Halide Analogues of D-Talose 2024. Olivier Lessard, Mathilde Grosset-Magagne, Paul A Johnson, Denis Giguère. DOI 10.3762/bxiv.2024.37.v1

Polyhalogenated Carbohydrates: Synthesis and Applications of Sugar Halides from Fluorine to Iodine European Journal of Organic Chemistry, 2024. Olivier Lessard, Danny Lainé, Denis Giguère. DOI 10.1002/ejoc.202400120

Synthesis and hydrolysis of aryl fluoroglycosides Journal of Fluorine Chemistry, 2024. Christina Leclerc, Jacob St-Gelais, Samy Cecioni, Denis Giguère. DOI 10.1016/j.jfluchem.2023.110232

Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus ACS Infectious Diseases, 2023. Salma Bricha, Mélanie Côté-Cyr, Thomas Tremblay, Phuong Trang Nguyen, Philippe St-Louis, Denis Giguère, Denis Archambault, Steve Bourgault. DOI 10.1021/acsinfecdis.2c00610

Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesis, and Antimalarial Activity ACS Medicinal Chemistry Letters, 2023. Thomas Tremblay, Catherine Bergeron, Dominic Gagnon, Christopher Bérubé, Normand Voyer, Dave Richard, Denis Giguère. DOI 10.1021/acsmedchemlett.2c00531

Synthesis of Lincosamide Analogues via Oxime Resin Aminolysis Synlett, 2022. Thomas Tremblay, Pénélope Haguette, Gabrielle Robert-Scott, Jessica B. Alcée, Christopher Bérubé, Catherine Bergeron, Normand Voyer, Denis Giguère. DOI 10.1055/a-1948-7153

Protecting-group-free synthesis of clevudine (<scp>l</scp>-FMAU), a treatment of the hepatitis B virus Organic & Biomolecular Chemistry, 2022. Thomas Tremblay, Jessica B. Alcée, Denis Giguère. DOI 10.1039/d2ob01814d

Synthesis of fluorinated thiodigalactoside analogues Carbohydrate Research, 2022. Jacob St-Gelais, Christina Leclerc, Denis Giguère. DOI 10.1016/j.carres.2021.108481

Fundamental curiosity of multivicinal inter-halide stereocenters Organic Chemistry Frontiers, 2022. Olivier Lessard, Danny Lainé, Charles-Émile Fecteau, Paul A. Johnson, Denis Giguère. DOI 10.1039/d2qo01433e

Synthetic development of sugar amino acid oligomers towards novel podophyllotoxin analogues Bioorganic & Medicinal Chemistry, 2021. Megan Bouchard, Thomas Tremblay, Marie-Pier Paré-Lacroix, Mathieu Gagné-Boulet, Sébastien Fortin, Denis Giguère. DOI 10.1016/j.bmc.2021.116501

Protecting-Group-Free Synthesis of GB1107: An Orally Active Galectin-3 Antagonist Synthesis, 2021. Jacob St-Gelais, Denis Giguère. DOI 10.1055/a-1517-7177

Annulative Dimerization of Carbohydrates: Synthesis of Complex <i>C</i> ₂ ‐Symmetrical 1,4‐Dioxane‐Sugar Hybrids European Journal of Organic Chemistry, 2021. Gabrielle Robert‐Scott, Jacob St‐Gelais, Denis Giguère. DOI 10.1002/ejoc.202100411

Polyfluoroglycoside Synthesis via Simple Alkylation of an Anomeric Hydroxyl Group: Access to Fluoroetoposide Analogues The Journal of Organic Chemistry, 2021. Thomas Tremblay, Jacob St-Gelais, Maxime Houde, Denis Giguère. DOI 10.1021/acs.joc.0c02841

From Carbohydrates to Complex Organofluorines: Synthesis, Conformation, and Lipophilicity of Multivicinal‐Fluorine‐Containing Hexitol Analogues Chemistry – A European Journal, 2021. Danny Lainé, Olivier Lessard, Jacob St‐Gelais, Denis Giguère. DOI 10.1002/chem.202004646

A glycan-based plasmonic sensor for prostate cancer diagnosis The Analyst, 2021. Mathieu Lamarre, Thomas Tremblay, Marc-Antoine Bansept, Karine Robitaille, Vincent Fradet, Denis Giguère, Denis Boudreau. DOI 10.1039/d1an00789k

Click approach to lipoic acid glycoconjugates. Carbohydrate chemistry: Proven synthetic methods, 2021. Thomas Tremblay, Antoine Carpentier, Charles Gauthier, Denis Giguère.

Alternative synthesis of 1,2,4,6-tetra-O-acetyl-3-deoxy-3-fluoro-α,β-D-glucopyranose. Carbohydrate chemistry: Proven synthetic methods, 2021. Jacob St-Gelais, Vincent Denavit, Danny Lainé, Kevin Muru, Denis Giguère.