Éric Boilard

• Centre de recherche ARThrite
• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en arthrite
• Centre de recherche en infectiologie

Financements des 2 dernières années

• Alicia Fortin, Maîtrise en microbiologie-immunologie - avec mémoire
• Ana Boisvert, Doctorat en neurosciences
• Evelyne Lemay, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Florian Tupin, Stage postdoctoral en médecine
• Guillaume Lemaire, Doctorat en médecine moléculaire
• Julia Corcoran, Maîtrise en microbiologie-immunologie - avec mémoire
• Marie-Laurence Gagné, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Mélina Monteil, Maîtrise en microbiologie-immunologie - avec mémoire
• Nikolaos Anagnostakis, Stage postdoctoral en médecine
• Rosalie Gingras, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Encadrements des 5 dernières années

• Ana Boisvert, Maîtrise en neurosciences - avec mémoire
• Audrée Laroche, Doctorat en microbiologie-immunologie
• Émilie Mercure, Maîtrise en microbiologie-immunologie - avec mémoire
• Etienne Doré, Doctorat en microbiologie-immunologie
• Florian Puhm, Stage postdoctoral en microbiologie-immunologie
• Frederik Denorme, Recherche postdoctorale en médecine
• Héléna Denis, Doctorat en neurobiologie
• Laurie Coutu-Godbout, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Marie Bellio, Stage postdoctoral en microbiologie-immunologie
• Océane Arevalo, Maîtrise en neurosciences - avec mémoire
• Sara Michel, Maîtrise en microbiologie-immunologie - avec mémoire
• Yaneisy-Nynoska Tremblay, Maîtrise en microbiologie-immunologie - avec mémoire
• Yann Becker, Stage postdoctoral en microbiologie-immunologie
• Yann Becker, Doctorat en médecine moléculaire

Travaux de recherche des 5 dernières années

Blood-brain barrier model architecture shapes peripheral immune cell trafficking in Parkinson’s disease 2026. Oceane Martinez, Lucile Gentile, Floriane Bretheau, Allison Yearwood, Oceane Arevalo, Flavia Natale Alves Martins Borba, Martine Boutin, Eric Boilard, Kelvin Luk, Francesca Cicchetti, Aurelie de Rus Jacquet.

Blood-brain barrier model architecture shapes peripheral immune cell trafficking in Parkinson's disease 2026. Oceane Martinez, Lucile Gentile, Floriane Bretheau, Allison Yearwood, Oceane Arevalo, Flavia Natale Alves Martins Borba, Martine Boutin, Eric Boilard, Kelvin Luk, Francesca Cicchetti, Aurelie de Rus Jacquet.

Mechanisms of von Willebrand factor activation driving no reflow in ischemic stroke Proceedings of the National Academy of Sciences of the United States of America, 2026. Laroche, Audrée, Rovito, Nick, Liu, Alice, Allaeys, Isabelle, Heitsch, Laura, Portier, Irina, Adeoye, Opeolu, Pizzella, Stephanie R, Giles, James A, Di Paola, Jorge, Lee, Jin-Moo, Bark, David, Campbell, Robert A, Mukherjee, Debanjan, Boilard, Éric, Denorme, Frederik. DOI 10.1073/pnas.2610397123

Clotting the Gap Between Mitochondria-Mediated Immunity and Mitochondrial Transfer Circulation research, 2026. Tupin, Florian, Gonzalez-Chapa, Jorge A, Chung, Jay H, Lood, Christian, Boilard, Eric. DOI 10.1161/CIRCRESAHA.125.326987

Megakaryocyte emperipolesis arms neutrophils via intracellular provisioning bioRxiv : the preprint server for biology, 2026. Kuehn, Julia K, Bae, Geon Ho, Darbousset, Roxane, Huang, Frank Y, Hall, Rebecca M, Schiffer, Josephin E, Miglani, Dhruv, Balu, Spoorthi, Wactor, Alexandra, Ghaloussi, Dorsaf, Barreiro, Olga, Guo, Li, Weyrich, Andrew S, Cleary, Simon J, Gunzer, Matthias, Iwakura, Yoichiro, Hoytema van Konijnenburg, David P, Italiano, Joseph E, Looney, Mark R, Boilard, Éric, Bergmeier, Wolfgang, Cunin, Pierre, Nigrovic, Peter A. DOI 10.64898/2026.08.04.742780

Megakaryocytes Internalize and Are Activated by Immune Complexes Circulation research, 2026. Puhm, Florian, Allaeys, Isabelle, Petito, Eleonora, Sang, Yaqiu, Tupin, Florian, Dos Santos Pereira Andrade, Ana, Doré, Etienne, Dubuc, Isabelle, Vaillancourt, Myriam, Dieudé, Mélanie, Hébert, Marie-Josée, Florea, Bogdan I, Trépanier, Patrick, Washington, Valance A, Senis, Yotis, Fortin, Paul R, Brisson, Alain R, Wolberg, Alisa S, Bury, Loredana, Flamand, Louis, Boilard, Eric. DOI 10.1161/CIRCRESAHA.125.327999

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation The Journal of clinical investigation, 2026. Bellio, Marie, Allaeys, Isabelle, Doré, Etienne, Vaillancourt, Myriam, Lévesque, Tania, Monteil, Mélina, Vallières, Nicolas, Desaulniers, Philippe, Bertrand, Nicolas, Washington, Valance A, Senis, Yotis, Lacroix, Steve, Fortin, Paul, Belleannée, Clémence, Boilard, Eric. DOI 10.1172/JCI195987

Hypercholesterolemia Impairs the Expression of Angiogenic MicroRNAs in Extracellular Vesicles Within Ischemic Skeletal Muscles Non-coding RNA, 2026. Raguema, Nozha, Dussault, Sylvie, Sawaya, Kevin, Desjarlais, Michel, Boilard, Eric, Chemtob, Sylvain, Rivard, Alain. DOI 10.3390/ncrna12010003

Antimitochondrial antibodies in systemic lupus erythematosus are associated with and predict nephritis, arterial vascular events, and mortality Annals of the rheumatic diseases, 2026. Becker, Yann L C, Boilard, Éric, Rollet-Labelle, Emmanuelle, Lood, Christian, Julien, Anne-Sophie, Abrahamowicz, Michal, Allaeys, Isabelle, Choi, May, Leclerc, Joannie, Lévesque, Tania, Urowitz, Murray, Hanly, John G, Gordon, Caroline, Bae, Sang-Cheol, Romero-Diaz, Juanita, Sanchez-Guerrero, Jorge, Clarke, Ann E, Bernatsky, Sasha, Wallace, Daniel, Isenberg, David, Rahman, Anisur, Merrill, Joan, Gladman, Dafna D, Bruce, Ian N, Petri, Michelle, Ginzler, Ellen, Dooley, Mary Anne, Ramsey-Goldman, Rosalind, Manzi, Susan, Jönsen, Andreas, Alarcόn, Graciela S, van Vollenhoven, Ronald, Aranow, Cynthia, Ruiz-Irastorza, Guillermo, Lim, Sam, Inanc, Murat, Kalunian, Kenneth, Jacobsen, Soren, Peschken, Christine, Kamen, Diane, Askanase, Anca, Buyon, Jill, Fortin, Paul R. DOI 10.1016/j.ard.2025.11.007

Remodeling of immune system functions by extracellular vesicles Frontiers in immunology, 2025. Neyrinck-Leglantier, Deborah, Tamagne, Marie, Ben Rayana, Raida, Many, Souganya, Pinheiro, Marion Klea, Delorme, Adèle Silane, Andrieu, Muriel, Boilard, Eric, Cognasse, Fabrice, Hamzeh-Cognasse, Hind, Perez-Patrigeon, Santiago, Lelievre, Jean-Daniel, Pirenne, France, Gallien, Sébastien, Vingert, Benoît. DOI 10.3389/fimmu.2025.1549107

Deciphering Platelets: Are They Cells or an Evolved Form of Extracellular Vesicles Circulation research, 2025. Boilard, Eric, Burger, Dylan, Buzas, Edit, Gresele, Paolo, Machlus, Kellie R, Mackman, Nigel, Siljander, Pia, Nieuwland, Rienk. DOI 10.1161/CIRCRESAHA.124.324721

sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models Molecular neurodegeneration, 2025. Yang, Cha, Du, Huan, Lee, Gwang Bin, Uematsu, Masaaki, He, Weiguo, Doré, Etienne, Yu, Weizhi, Sanford, Ethan J, Smolka, Marcus B, Boilard, Eric, Baskin, Jeremy M, Hao, Ling, Hu, Fenghua. DOI 10.1186/s13024-025-00863-8

Mental health among healthcare workers during COVID-19: a study to oversee the impact of the risk perception and relationship with inflammation from blood-based extracellular vesicles Frontiers in public health, 2025. Canivet, Coraline, Hébert, Thalie, Boilard, Eric, Morin, Charles M, Deslauriers, Jessica. DOI 10.3389/fpubh.2025.1560129

Impact of pre- and post-thaw processing on recovery and fitness of cord blood mononuclear cells as starting material for cell therapy Cytotherapy, 2025. Coutu-Godbout, Laurie, Perreault, Josée, Fournier, Diane, Boilard, Éric, Trépanier, Patrick. DOI 10.1016/j.jcyt.2025.09.003

Endothelial extracellular vesicle miR-423-5p regulates microvascular homeostasis and renal function after ischemia-reperfusion injury JCI insight, 2025. Migneault, Francis, Kim, Hyunyun, Doreille, Alice, Lan, Shanshan, Gendron, Alexis, Normand, Marie-Hélène, Rimbaud, Annie Karakeussian, Dupont, Martin, Bourdeau, Isabelle, Bonneil, Éric, Turgeon, Julie, Dussault, Sylvie, Thibault, Pierre, Dieudé, Mélanie, Boilard, Éric, Rivard, Alain, Cardinal, Héloïse, Hébert, Marie-Josée. DOI 10.1172/jci.insight.181937

Megakaryocytes as mitochondria factories: potential donors for mitochondria transplantation Current opinion in hematology, 2025. Mercure, Émilie, Pelletier, Martin, Boilard, Éric. DOI 10.1097/MOH.0000000000000889

Recommendations for mitochondria transfer and transplantation nomenclature and characterization Nature metabolism, 2025. Brestoff, Jonathan R, Singh, Keshav K, Aquilano, Katia, Becker, Lance B, Berridge, Michael V, Boilard, Eric, Caicedo, Andrés, Crewe, Clair, Enríquez, José Antonio, Gao, Jianqing, Gustafsson, Åsa B, Hayakawa, Kazuhide, Khoury, Maroun, Lee, Yun-Sil, Lettieri-Barbato, Daniele, Luz-Crawford, Patricia, McBride, Heidi M, McCully, James D, Nakai, Ritsuko, Neuzil, Jiri, Picard, Martin, Rabchevsky, Alexander G, Rodriguez, Anne-Marie, Sengupta, Shiladitya, Sercel, Alexander J, Suda, Toshio, Teitell, Michael A, Thierry, Alain R, Tian, Rong, Walker, Melanie, Zheng, Minghao. DOI 10.1038/s42255-024-01200-x

Erythrocyte-derived extracellular vesicles transcytose across the blood-brain barrier to induce Parkinson's disease-like neurodegeneration Fluids and barriers of the CNS, 2025. Denis, Hélèna L, de Rus Jacquet, Aurélie, Alpaugh, Melanie, Panisset, Michel, Barker, Roger A, Boilard, Éric, Cicchetti, Francesca. DOI 10.1186/s12987-025-00646-9

Targeting Cytokines: Evaluating the Potential of Mesenchymal Stem Cell Derived Extracellular Vesicles in the Management of COVID-19 Stem cell reviews and reports, 2025. Schultz, Iago Carvalho, Dos Santos Pereira Andrade, Ana Claudia, Dubuc, Isabelle, Laroche, Audrée, Allaeys, Isabelle, Doré, Etienne, Bertrand, Nicolas, Vallières, Luc, Fradette, Julie, Flamand, Louis, Wink, Marcia Rosangela, Boilard, Eric. DOI 10.1007/s12015-024-10794-4

Secretory phospholipase A2-IIA targets bacterial extracellular vesicles to modulate immune signaling Communications biology, 2025. Doré, Etienne, Bérubé, Ève, Greffard, Karine, Morozumi, Satoshi, Chénard, Valérie, Lemaire, Guillaume, Allaeys, Isabelle, Lévesque, Tania, Rudkowska, Iwona, Brisson, Alain R, Lambeau, Gérard, Bertrand, Nicolas, Boissinot, Maurice, Arita, Makoto, Bilodeau, Jean-François, Isabel, Sandra, Boilard, Eric. DOI 10.1038/s42003-025-09025-4

Deficiency in platelet 12-lipoxygenase exacerbates inflammation and disease severity during SARS-CoV-2 infection Proceedings of the National Academy of Sciences of the United States of America, 2025. Dos S P Andrade, Ana Claudia, Lacasse, Emile, Dubuc, Isabelle, Gudimard, Leslie, Gravel, Annie, Puhm, Florian, Campolina-Silva, Gabriel, Queiroz-Junior, Celso, Allaeys, Isabelle, Prunier, Julien, Azeggouar Wallen, Oumaima, Dumais, Élizabeth, Belleannée, Clémence, Droit, Arnaud, Flamand, Nicolas, Boilard, Éric, Flamand, Louis. DOI 10.1073/pnas.2420441122

Selective Enrichment of Angiomirs in Extracellular Vesicles Released from Ischemic Skeletal Muscles: Potential Role in Angiogenesis and Neovascularization Cells, 2024. Dussault, Sylvie, Desjarlais, Michel, Raguema, Nozha, Boilard, Eric, Chemtob, Sylvain, Rivard, Alain. DOI 10.3390/cells13151243

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow Blood advances, 2024. Allaeys, Isabelle, Lemaire, Guillaume, Leclercq, Mickaël, Lacasse, Emile, Fleury, Maude, Dubuc, Isabelle, Gudimard, Leslie, Puhm, Florian, Tilburg, Julia, Stone, Andrew, Machlus, Kellie R, Droit, Arnaud, Flamand, Louis, Boilard, Eric. DOI 10.1182/bloodadvances.2023012367

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches Journal of extracellular vesicles, 2024. Welsh, Joshua A, Goberdhan, Deborah C I, O'Driscoll, Lorraine, Buzas, Edit I, Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A P, Erdbrügger, Uta, Falcon-Perez, Juan M, Fu, Qing-Ling, Hill, Andrew F, Lenassi, Metka, Lim, Sai Kiang, Mahoney, Mỹ G, Mohanty, Sujata, Möller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C, Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M, Brucale, Marco, Burger, Dylan, Carney, Randy P, Cocucci, Emanuele, Crescitelli, Rossella, Hanser, Edveena, Harris, Adrian L, Haughey, Norman J, Hendrix, An, Ivanov, Alexander R, Jovanovic-Talisman, Tijana, Kruh-Garcia, Nicole A, Ku'ulei-Lyn Faustino, Vroniqa, Kyburz, Diego, Lässer, Cecilia, Lennon, Kathleen M, Lötvall, Jan, Maddox, Adam L, Martens-Uzunova, Elena S, Mizenko, Rachel R, Newman, Lauren A, Ridolfi, Andrea, Rohde, Eva, Rojalin, Tatu, Rowland, Andrew, Saftics, Andras, Sandau, Ursula S, Saugstad, Julie A, Shekari, Faezeh, Swift, Simon, Ter-Ovanesyan, Dmitry, Tosar, Juan P, Useckaite, Zivile, Valle, Francesco, Varga, Zoltan, van der Pol, Edwin, van Herwijnen, Martijn J C, Wauben, Marca H M, Wehman, Ann M, Williams, Sarah, Zendrini, Andrea, Zimmerman, Alan J, MISEV Consortium, Théry, Clotilde, Witwer, Kenneth W, Arif, Syrine, Bazié, Wilfried W, Belleannée, Clémence, Boilard, Eric, Coutant, Kelly, Doré, Etienne, Gilbert, Caroline, Landreville, Solange, Puhm, Florian, Vinay, Ludovic. DOI 10.1002/jev2.12404

Platelet extracellular vesicles preserve lymphatic endothelial cell integrity and enhance lymphatic vessel function Communications biology, 2024. Vachon, Laurent, Jean, Gabriel, Milasan, Andreea, Babran, Sara, Lacroix, Elizabeth, Guadarrama Bello, Dainelys, Villeneuve, Louis, Rak, Janusz, Nanci, Antonio, Mihalache-Avram, Teodora, Tardif, Jean-Claude, Finnerty, Vincent, Ruiz, Matthieu, Boilard, Eric, Tessier, Nolwenn, Martel, Catherine. DOI 10.1038/s42003-024-06675-8

Vascular injury derived apoptotic exosome-like vesicles trigger autoimmunity Journal of translational autoimmunity, 2024. Juillard, Sandrine, Karakeussian-Rimbaud, Annie, Normand, Marie-Hélène, Turgeon, Julie, Veilleux-Trinh, Charlotte, C Robitaille, Alexa, Rauch, Joyce, Chruscinski, Andrzej, Grandvaux, Nathalie, Boilard, Éric, Hébert, Marie-Josée, Dieudé, Mélanie. DOI 10.1016/j.jtauto.2024.100250

Bone marrow-derived myeloid cells transiently colonize the brain during postnatal development and interact with glutamatergic synapses iScience, 2024. Carrier, Micaël, Robert, Marie-Ève, St-Pierre, Marie-Kim, Ibáñez, Fernando González, Gonçalves de Andrade, Elisa, Laroche, Audrée, Picard, Katherine, Vecchiarelli, Haley A, Savage, Julie C, Boilard, Éric, Desjardins, Michèle, Tremblay, Marie-Ève. DOI 10.1016/j.isci.2024.110037

IgG hexamers initiate complement-dependent acute lung injury The Journal of clinical investigation, 2024. Cleary, Simon J, Seo, Yurim, Tian, Jennifer J, Kwaan, Nicholas, Bulkley, David P, Vidarsson, Gestur, Boilard, Éric, Spirig, Rolf, Zimring, James C, Looney, Mark R, Bentlage, Arthur Eh. DOI 10.1172/JCI178351

Immunoregulatory molecule expression on extracellular microvesicles in people living with HIV Frontiers in immunology, 2024. Neyrinck-Leglantier, Deborah, Tamagne, Marie, Ben Rayana, Raida, Many, Souganya, Vingert, Paul, LeGagneux, Julie, Delorme, Adèle Silane, Andrieu, Muriel, Boilard, Eric, Cognasse, Fabrice, Hamzeh-Cognasse, Hind, Perez-Patrigeon, Santiago, Lelievre, Jean-Daniel, Pirenne, France, Gallien, Sébastien, Vingert, Benoît. DOI 10.3389/fimmu.2024.1354065

Bacterial extracellular vesicles and their interplay with the immune system Pharmacology & therapeutics, 2023. Doré, Etienne, Boilard, Eric. DOI 10.1016/j.pharmthera.2023.108443

Peripheral megakaryocytes sound the alarm in COVID-19 Blood advances, 2023. Boilard, Eric, Machlus, Kellie R. DOI 10.1182/bloodadvances.2023010201

Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36 bioRxiv : the preprint server for biology, 2023. Barrachina, Maria N, Pernes, Gerard, Becker, Isabelle C, Allaeys, Isabelle, Hirsch, Thomas I, Groeneveld, Dafna J, Khan, Abdullah O, Freire, Daniela, Guo, Karen, Carminita, Estelle, Morgan, Pooranee K, Mellett, Natalie A, Wei, Zimu, Almazni, Ibrahim, Italiano, Joseph E, Luyendyk, James, Meikle, Peter J, Puder, Mark, Morgan, Neil V, Boilard, Eric, Murphy, Andrew J, Machlus, Kellie R, Collins, Thomas J. DOI 10.1101/2023.02.12.527706

Diversity of Megakaryocytes Arteriosclerosis, thrombosis, and vascular biology, 2023. Puhm, Florian, Laroche, Audrée, Boilard, Eric. DOI 10.1161/ATVBAHA.123.318782

The role of platelets in immune-mediated inflammatory diseases Nature reviews. Immunology, 2023. Scherlinger, Marc, Richez, Christophe, Tsokos, George C, Boilard, Eric, Blanco, Patrick. DOI 10.1038/s41577-023-00834-4

Lipidomic analysis of differently prepared platelet concentrates in additive solution during storage Blood transfusion = Trasfusione del sangue, 2023. Duchez, Anne-Claire, Fauteux-Daniel, Sébastien, Ebermeyer, Theo, Heestermans, Marco, Arthaud, Charles-Antoine, Eyraud, Marie-Ange, Prier, Amélie, Audoux, Estelle, Portais, Jean-Charles, Bertrand-Michel, Justine, Garraud, Olivier, Hamzeh-Cognasse, Hind, Boilard, Eric, Cognasse, Fabrice. DOI 10.2450/2022.0144-22

MIBlood-EV: Minimal information to enhance the quality and reproducibility of blood extracellular vesicle research Journal of extracellular vesicles, 2023. Lucien, Fabrice, Gustafson, Dakota, Lenassi, Metka, Li, Bo, Teske, Jacob J, Boilard, Eric, von Hohenberg, Katharina Clemm, Falcón-Perez, Juan Manual, Gualerzi, Alice, Reale, Antonia, Jones, Jennifer C, Lässer, Cecilia, Lawson, Charlotte, Nazarenko, Irina, O'Driscoll, Lorraine, Pink, Ryan, Siljander, Pia R-M, Soekmadji, Carolina, Hendrix, An, Welsh, Joshua A, Witwer, Kenneth W, Nieuwland, Rienk. DOI 10.1002/jev2.12385

SARS-CoV-2 Nsp2 Contributes to Inflammation by Activating NF-κB Viruses, 2023. Lacasse, Émile, Gudimard, Leslie, Dubuc, Isabelle, Gravel, Annie, Allaeys, Isabelle, Boilard, Éric, Flamand, Louis. DOI 10.3390/v15020334

Bioactive lipids as biomarkers of adverse reactions associated with apheresis platelet concentrate transfusion Frontiers in immunology, 2023. Duchez, Anne-Claire, Fauteux-Daniel, Sébastien, Sut, Caroline, Ebermeyer, Theo, Heestermans, Marco, Arthaud, Charles-Antoine, Eyraud, Marie-Ange, Prier, Amélie, Audoux, Estelle, Bertrand-Michel, Justine, Payrastre, Bernard, Garraud, Olivier, Boilard, Eric, Hamzeh-Cognasse, Hind, Cognasse, Fabrice. DOI 10.3389/fimmu.2023.1031968

Thermoneutrality and severe malaria: investigating the effect of warmer environmental temperatures on the inflammatory response and disease progression Frontiers in immunology, 2023. Vialard, Fiorella, Allaeys, Isabelle, Dong, George, Phan, Minh Phuong, Singh, Urvashi, Hébert, Marie Josée, Dieudé, Mélanie, Langlais, David, Boilard, Eric, Labbé, David P, Olivier, Martin. DOI 10.3389/fimmu.2023.1128466

Platelet extracellular vesicles and their mitochondrial content improve the mitochondrial bioenergetics of cellular immune recipients Transfusion, 2023. Pelletier, Martin, Breton, Yann, Allaeys, Isabelle, Becker, Yann, Benson, Tom, Boilard, Eric. DOI 10.1111/trf.17524

Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis Cell death & disease, 2023. Brodeur, Alexandre, Migneault, Francis, Lanoie, Maude, Beillevaire, Déborah, Turgeon, Julie, Karakeussian-Rimbaud, Annie, Thibodeau, Nicolas, Boilard, Éric, Dieudé, Mélanie, Hébert, Marie-Josée. DOI 10.1038/s41419-023-05991-x

Author Correction: The role of platelets in immune-mediated inflammatory diseases Nature reviews. Immunology, 2023. Scherlinger, Marc, Richez, Christophe, Tsokos, George C, Boilard, Eric, Blanco, Patrick. DOI 10.1038/s41577-023-00869-7

The origin of the megakaryocyte Nature cardiovascular research, 2022. Machlus, Kelly R, Boilard, Éric. DOI 10.1038/s44161-022-00099-5

Autolysosomes and caspase-3 control the biogenesis and release of immunogenic apoptotic exosomes Cell death & disease, 2022. Beillevaire, Déborah, Migneault, Francis, Turgeon, Julie, Gingras, Diane, Rimbaud, Annie Karakeussian, Marcoux, Geneviève, Spino, Crysta, Thibodeau, Nicolas, Bonneil, Eric, Thibault, Pierre, Boilard, Éric, Dieudé, Mélanie, Hébert, Marie-Josée. DOI 10.1038/s41419-022-04591-5

The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury Nature communications, 2022. Bretheau, Floriane, Castellanos-Molina, Adrian, Bélanger, Dominic, Kusik, Maxime, Mailhot, Benoit, Boisvert, Ana, Vallières, Nicolas, Lessard, Martine, Gunzer, Matthias, Liu, Xiaoyu, Boilard, Éric, Quan, Ning, Lacroix, Steve. DOI 10.1038/s41467-022-33463-x

Megakaryocytes and platelets embrace diversity in face of adversity Journal of thrombosis and haemostasis : JTH, 2022. Puhm, Florian, Boilard, Eric. DOI 10.1111/jth.15761

Platelet extracellular vesicles and the secretory interactome join forces in health and disease Immunological reviews, 2022. Boilard, Eric, Bellio, Marie. DOI 10.1111/imr.13119

Red blood cell-derived phosphatidylserine positive extracellular vesicles are associated with past thrombotic events in patients with systemic erythematous lupus Lupus science & medicine, 2022. Hasse, Stephan, Julien, Anne-Sophie, Duchez, Anne-Claire, Zhao, Chenqi, Boilard, Eric, Fortin, Paul R, Bourgoin, Sylvain G. DOI 10.1136/lupus-2021-000605

The role of mitochondria in rheumatic diseases Nature reviews. Rheumatology, 2022. Becker, Yann L C, Duvvuri, Bhargavi, Fortin, Paul R, Lood, Christian, Boilard, Eric. DOI 10.1038/s41584-022-00834-z

Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota JCI insight, 2022. Miki, Yoshimi, Taketomi, Yoshitaka, Kidoguchi, Yuh, Yamamoto, Kei, Muramatsu, Kazuaki, Nishito, Yasumasa, Park, Jonguk, Hosomi, Koji, Mizuguchi, Kenji, Kunisawa, Jun, Soga, Tomoyoshi, Boilard, Eric, B Gowda, Siddabasave Gowda, Ikeda, Kazutaka, Arita, Makoto, Murakami, Makoto. DOI 10.1172/jci.insight.152611

The interaction of secreted phospholipase A2-IIA with the microbiota alters its lipidome and promotes inflammation JCI insight, 2022. Doré, Etienne, Joly-Beauparlant, Charles, Morozumi, Satoshi, Mathieu, Alban, Lévesque, Tania, Allaeys, Isabelle, Duchez, Anne-Claire, Cloutier, Nathalie, Leclercq, Mickaël, Bodein, Antoine, Payré, Christine, Martin, Cyril, Petit-Paitel, Agnes, Gelb, Michael H, Rangachari, Manu, Murakami, Makoto, Davidovic, Laetitia, Flamand, Nicolas, Arita, Makoto, Lambeau, Gérard, Droit, Arnaud, Boilard, Eric. DOI 10.1172/jci.insight.152638

Identification of Mitofusin 1 and Complement Component 1q Subcomponent Binding Protein as Mitochondrial Targets in Systemic Lupus Erythematosus Arthritis & rheumatology (Hoboken, N.J.), 2022. Becker, Yann L C, Gagné, Jean-Philippe, Julien, Anne-Sophie, Lévesque, Tania, Allaeys, Isabelle, Gougeard, Nadine, Rubio, Vicente, Boisvert, François-Michel, Jean, Dominique, Wagner, Eric, Poirier, Guy G, Fortin, Paul R, Boilard, Éric. DOI 10.1002/art.42082

Platelet extracellular vesicles in COVID-19: Potential markers and makers Journal of leukocyte biology, 2022. Puhm, Florian, Flamand, Louis, Boilard, Eric. DOI 10.1002/JLB.3MIR0221-100R

Platelet activation by SARS-CoV-2 implicates the release of active tissue factor by infected cells Blood advances, 2022. Puhm, Florian, Allaeys, Isabelle, Lacasse, Emile, Dubuc, Isabelle, Galipeau, Yannick, Zaid, Younes, Khalki, Loubna, Belleannée, Clemence, Durocher, Yves, Brisson, Alain R, Wolberg, Alisa S, Langlois, Marc-André, Flamand, Louis, Boilard, Eric. DOI 10.1182/bloodadvances.2022007444

Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis Blood advances, 2022. Laroche, Audree, Soulet, Denis, Bazin, Marc, Levesque, Tania, Allaeys, Isabelle, Vallières, Nicolas, Gunzer, Matthias, Flamand, Louis, Lacroix, Steve, Boilard, Eric. DOI 10.1182/bloodadvances.2021006728

Cytokines and Lipid Mediators of Inflammation in Lungs of SARS-CoV-2 Infected Mice Frontiers in immunology, 2022. Dubuc, Isabelle, Prunier, Julien, Lacasse, Émile, Gravel, Annie, Puhm, Florian, Allaeys, Isabelle, Archambault, Anne-Sophie, Gudimard, Leslie, Villano, Rosaria, Droit, Arnaud, Flamand, Nicolas, Boilard, Éric, Flamand, Louis. DOI 10.3389/fimmu.2022.893792

Interplay between LPA2 and LPA3 in LPA-mediated phosphatidylserine cell surface exposure and extracellular vesicles release by erythrocytes Biochemical pharmacology, 2021. Hasse, Stephan, Duchez, Anne-Claire, Fortin, Paul, Boilard, Eric, Bourgoin, Sylvain G. DOI 10.1016/j.bcp.2021.114667

Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19 The Journal of allergy and clinical immunology, 2021. Zaid, Younes, Doré, Étienne, Dubuc, Isabelle, Archambault, Anne-Sophie, Flamand, Olivier, Laviolette, Michel, Flamand, Nicolas, Boilard, Éric, Flamand, Louis. DOI 10.1016/j.jaci.2021.05.032

Role of platelets and megakaryocytes in adaptive immunity Platelets, 2021. Marcoux, Genevieve, Laroche, Audrée, Espinoza Romero, Jenifer, Boilard, Eric. DOI 10.1080/09537104.2020.1786043

High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021. Archambault, Anne-Sophie, Zaid, Younes, Rakotoarivelo, Volatiana, Turcotte, Caroline, Dore, Etienne, Dubuc, Isabelle, Martin, Cyril, Flamand, Olivier, Amar, Youssef, Cheikh, Amine, Fares, Hakima, El Hassani, Amine, Tijani, Youssef, Cote, Andreanne, Laviolette, Michel, Boilard, Eric, Flamand, Louis, Flamand, Nicolas. DOI 10.1096/fj.202100540R

Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts Transplantation direct, 2021. Mazilescu, Laura I, Urbanellis, Peter, Kaths, Moritz J, Ganesh, Sujani, Goto, Toru, Noguchi, Yuki, John, Rohan, Konvalinka, Ana, Mucsi, Istvan, Ghanekar, Anand, Bagli, Darius J, Turgeon, Julie, Karakeusian Rimbaud, Annie, Hébert, Marie-Josée, Dieudé, Mélanie, Alleys, Isabelle, Dore, Etienne, Boilard, Eric, Overkleeft, Herman S, Willems, Lianne I, Robinson, Lisa A, Selzner, Markus. DOI 10.1097/TXD.0000000000001218

Platelet reactivity to thrombin differs between patients with COVID-19 and those with ARDS unrelated to COVID-19 Blood advances, 2021. Zaid, Younes, Guessous, Fadila, Puhm, Florian, Elhamdani, Wail, Chentoufi, Lamyae, Morris, Andrew Conway, Cheikh, Amine, Jalali, Farid, Boilard, Eric, Flamand, Louis. DOI 10.1182/bloodadvances.2020003513

Platelet Extracellular Vesicles: Beyond the Blood Arteriosclerosis, thrombosis, and vascular biology, 2021. Puhm, Florian, Boilard, Eric, Machlus, Kellie R. DOI 10.1161/ATVBAHA.120.314644

Location is everything when it comes to megakaryocyte function The Journal of clinical investigation, 2021. Boilard, Eric, Machlus, Kellie R. DOI 10.1172/JCI144964

Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules Blood, 2021. Marcoux, Genevieve, Laroche, Audrée, Hasse, Stephan, Bellio, Marie, Mbarik, Maroua, Tamagne, Marie, Allaeys, Isabelle, Zufferey, Anne, Lévesque, Tania, Rebetz, Johan, Karakeussian-Rimbaud, Annie, Turgeon, Julie, Bourgoin, Sylvain G, Hamzeh-Cognasse, Hind, Cognasse, Fabrice, Kapur, Rick, Semple, John W, Hébert, Marie-Josée, Pirenne, France, Florea, Bogdan I, Dieude, Mélanie, Vingert, Benoît, Boilard, Eric, Overkleeft, Herman S. DOI 10.1182/blood.2020009957

Is there a role for the ACE2 receptor in SARS-CoV-2 interactions with platelets Journal of thrombosis and haemostasis : JTH, 2021. Campbell, Robert A, Boilard, Eric, Rondina, Matthew T. DOI 10.1111/jth.15156

Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis International journal of molecular sciences, 2021. Zhao, Yang, Hasse, Stephan, Vaillancourt, Myriam, Zhao, Chenqi, Davis, Lynn, Boilard, Eric, Fortin, Paul, Di Battista, John, Poubelle, Patrice E, Bourgoin, Sylvain G. DOI 10.3390/ijms222312685

Platelet Extracellular Vesicles Arteriosclerosis, Thrombosis, and Vascular Biology, 2021. Florian Puhm, Eric Boilard, Kellie R. Machlus.

Platelets release mitochondrial antigens in systemic lupus erythematosus Science translational medicine, 2021. Melki, Imene, Allaeys, Isabelle, Tessandier, Nicolas, Levesque, Tania, Cloutier, Nathalie, Laroche, Audree, Vernoux, Nathalie, Becker, Yann, Benk-Fortin, Hadrien, Zufferey, Anne, Rollet-Labelle, Emmanuelle, Pouliot, Marc, Poirier, Guy, Patey, Natacha, Belleannee, Clemence, Soulet, Denis, McKenzie, Steven E, Brisson, Alain, Tremblay, Marie-Eve, Lood, Christian, Fortin, Paul R, Boilard, Eric. DOI 10.1126/scitranslmed.aav5928