Jacques Corbeil

• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en données massives
• Centre de recherche en infectiologie
• Centre Nutrition, santé et société
• Institut Intelligence et Données

Financements des 2 dernières années

• Anthony Lavertu, Maîtrise en informatique - avec mémoire
• Elina Francovic-Fontaine, Doctorat en médecine moléculaire
• Francis Brière, Doctorat en médecine moléculaire
• Juan Manuel Dominguez, Maîtrise en médecine moléculaire - avec mémoire
• Thibaud Godon, Doctorat en informatique
• Yesmine Sahnoun, Maîtrise en informatique - avec mémoire
• Zhiqiang Pang, Stage postdoctoral en médecine

Encadrements des 5 dernières années

• Baptiste Bauvin, Doctorat en informatique
• Claudia Carpentier, Stage postdoctoral en médecine
• Elina Francovic-Fontaine, Maîtrise en médecine moléculaire - avec mémoire
• Francis Brière, Maîtrise en médecine moléculaire - avec mémoire
• Guillaume Edouard Marie Bachelot, Stage postdoctoral en médecine
• Jehane Abed, Doctorat en microbiologie-immunologie
• Maxime Déraspe, Stage postdoctoral en médecine
• Minja Velimirovic, Doctorat en médecine moléculaire
• Paul George, Stage postdoctoral en génomique
• Sewagnouin Rogia Kpanou, Doctorat en informatique

Travaux de recherche des 5 dernières années

Turncoat antibodies unmasked in a model of autoimmune demyelination: From biology to therapy Proceedings of the National Academy of Sciences, 2025. Reza Taghipour-Mirakmahaleh, Françoise Morin, Yu Zhang, Louis Bourhoven, Louis-Charles Béland, Qun Zhou, Julie Jaworski, Anna Park, Juan Manuel Dominguez, Jacques Corbeil, Eoin P. Flanagan, Romain Marignier, Catherine Larochelle, Steven M. Kerfoot, Luc Vallières. DOI 10.1073/pnas.2424988122

Extracting a COVID-19 signature from a multi-omic dataset Frontiers in Bioinformatics, 2025. Baptiste Bauvin, Thibaud Godon, Guillaume Bachelot, Claudia Carpentier, Riikka Huusaari, Maxime Deraspe, Juho Rousu, Caroline Quach, Jacques Corbeil. DOI 10.3389/fbinf.2025.1645785

Comparative genomics of Pseudomonas paraeruginosa Journal of Bacteriology, 2025. Maxime Déraspe, Lori L. Burrows, Romé Voulhoux, Daniela Centrón, Jacques Corbeil, Paul H. Roy. DOI 10.1128/jb.00149-25

On Selecting Robust Approaches for Learning Predictive Biomarkers in Metabolomics Data Sets Analytical Chemistry, 2025. Thibaud Godon, Pier-Luc Plante, Jacques Corbeil, Pascal Germain, Alexandre Drouin. DOI 10.1021/acs.analchem.5c01049

Associations between circulating amino acids and metabolic dysfunction-associated steatotic liver disease in individuals living with severe obesity. Physiological reports, 2025. Maltais-Payette I, Bourgault J, Gauthier MF, Biertho L, Marceau S, Julien F, Mitchell PL, Couture C, Brière F, Corbeil J, Arsenault BJ, Tchernof A. DOI 10.14814/phy2.70171

Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy 2024. Taghipour-Mirakmahaleh R, Morin F, Zhang Y, Bourhoven L, Béland L, Zhou Q, Jaworski J, Park A, Dominguez JM, Corbeil J, Flanagan EP, Marignier R, Vallières L. DOI 10.1101/2024.12.03.623846

Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. Dzieciolowska S, Charest H, Roy T, Fafard J, Carazo S, Levade I, Longtin J, Parkes L, Beaulac SN, Villeneuve J, Savard P, Corbeil J, De Serres G, Longtin Y. DOI 10.1093/cid/ciad535

Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases low-density lipoprotein apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial. The American journal of clinical nutrition, 2024. Desjardins LC, Brière F, Tremblay AJ, Rancourt-Bouchard M, Drouin-Chartier JP, Corbeil J, Lemelin V, Charest A, Schaefer EJ, Lamarche B, Couture P. DOI 10.1016/j.ajcnut.2024.03.015

Learning self-supervised molecular representations for drug-drug interaction prediction. BMC bioinformatics, 2024. Kpanou R, Dallaire P, Rousseau E, Corbeil J. DOI 10.1186/s12859-024-05643-7

Phylogenomic insights into evolutionary trajectories of multidrug resistant S. pneumoniae CC271 over a period of 14 years in China. Genome medicine, 2023. Zeng Y, Song Y, Cui L, Wu Q, Wang C, Coelho AC, Zhang G, Wei D, Li C, Zhang J, Corbeil J, Li Y, Feng J. DOI 10.1186/s13073-023-01200-8

Timing and Predictors of Loss of Infectivity among Healthcare Workers with Primary and Recurrent COVID-19: a Prospective Observational Cohort Study 2023. Dzieciolowska S, Charest H, Roy T, Fafard J, Carazo S, Levade I, Longtin J, Parkes L, Beaulac SN, Villeneuve J, Savard P, Corbeil J, Serres GD, Longtin Y. DOI 10.1101/2023.06.16.23291449

Characterization of vancomycin-resistance <i>vanD</i> gene clusters in the human intestinal microbiota by metagenomics and culture-enriched metagenomics. JAC-antimicrobial resistance, 2023. Brochu E, Huletsky A, Boudreau DK, Raymond F, Bérubé È, Ouameur AA, Frenette J, Boissinot M, Corbeil J, Bergeron MG. DOI 10.1093/jacamr/dlad026

Gut metagenome profile of the Nunavik Inuit youth is distinct from industrial and non-industrial counterparts. Communications biology, 2022. Abed JY, Godon T, Mehdaoui F, Plante PL, Boissinot M, Bergeron MG, Bélanger RE, Muckle G, Poliakova N, Ayotte P, Corbeil J, Rousseau E. DOI 10.1038/s42003-022-04372-y

MOT: a Multi-Omics Transformer for multiclass classification tumour types predictions 2022. Osseni MA, Tossou P, Laviolette F, Corbeil J. DOI 10.21203/rs.3.rs-1348696/v2

Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine. Frontiers in immunology, 2022. Nantel S, Bourdin B, Adams K, Carbonneau J, Rabezanahary H, Hamelin MÈ, McCormack D, Savard P, Longtin Y, Cheng MP, De Serres G, Corbeil J, Gilca V, Decaluwe H. DOI 10.3389/fimmu.2022.930252

Antimicrobial Resistance in the Environment: Towards Elucidating the Roles of Bioaerosols in Transmission and Detection of Antibacterial Resistance Genes. Antibiotics (Basel, Switzerland), 2022. George PBL, Rossi F, St-Germain MW, Amato P, Badard T, Bergeron MG, Boissinot M, Charette SJ, Coleman BL, Corbeil J, Culley AI, Gaucher ML, Girard M, Duchaine C. DOI 10.3390/antibiotics11070974

Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity. Amino acids, 2022. Maltais-Payette I, Vijay J, Simon MM, Corbeil J, Brière F, Grundberg E, Tchernof A. DOI 10.1007/s00726-022-03181-1

Flexible protein database based on amino acid k-mers. Scientific reports, 2022. Déraspe M, Boisvert S, Laviolette F, Roy PH, Corbeil J. DOI 10.1038/s41598-022-12843-9

The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers. Influenza and other respiratory viruses, 2022. Racine É, Boivin G, Longtin Y, McCormack D, Decaluwe H, Savard P, Cheng MP, Hamelin MÈ, Carbonneau J, Tadount F, Adams K, Bourdin B, Nantel S, Quach-Thanh C. DOI 10.1111/irv.12997

Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease. Metabolites, 2022. Gobeil É, Maltais-Payette I, Taba N, Brière F, Ghodsian N, Abner E, Bourgault J, Gagnon E, Manikpurage HD, Couture C, Mitchell PL, Mathieu P, Arsenault BJ. DOI 10.3390/metabo12050440

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response. Journal of neuroinflammation, 2022. Uyar O, Dominguez JM, Bordeleau M, Lapeyre L, Ibáñez FG, Vallières L, Tremblay ME, Corbeil J, Boivin G. DOI 10.1186/s12974-022-02437-7

Complete Genome Sequences of Klebsiella michiganensis and Citrobacter farmeri, KPC-2-Producers Serially Isolated from a Single Patient. Antibiotics (Basel, Switzerland), 2021. Abed JY, Déraspe M, Bérubé È, D'Iorio M, Dewar K, Boissinot M, Corbeil J, Bergeron MG, Roy PH. DOI 10.3390/antibiotics10111408

Optimization & Characterization of Interdigitated Electrodes for Microbial Growth Monitoring. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021. Hosseini SN, Sarati Das P, Gagnon-Turcotte G, Bl-George P, Messaddeq Y, Corbeil J, Gosselin B. DOI 10.1109/embc46164.2021.9630056

On the robustness of generalization of drug-drug interaction models. BMC bioinformatics, 2021. Kpanou R, Osseni MA, Tossou P, Laviolette F, Corbeil J. DOI 10.1186/s12859-021-04398-9

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis. Scientific reports, 2021. Uyar O, Plante PL, Piret J, Venable MC, Carbonneau J, Corbeil J, Boivin G. DOI 10.1038/s41598-021-98047-z

Exploring polypharmacy with artificial intelligence: data analysis protocol. BMC medical informatics and decision making, 2021. Sirois C, Khoury R, Durand A, Deziel PL, Bukhtiyarova O, Chiu Y, Talbot D, Bureau A, Després P, Gagné C, Laviolette F, Savard AM, Corbeil J, Simard M. DOI 10.1186/s12911-021-01583-x

Serratia marcescens SCH909 as reservoir and source of genetic elements related to wide dissemination of antimicrobial resistance mechanisms. FEMS microbiology letters, 2021. Gambino AS, Déraspe M, Álvarez VE, Quiroga MP, Corbeil J, Roy PH, Centrón D. DOI 10.1093/femsle/fnab086

Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic. Environmental microbiology, 2021. Jungblut AD, Raymond F, Dion MB, Moineau S, Mohit V, Nguyen GQ, Déraspe M, Francovic-Fontaine É, Lovejoy C, Culley AI, Corbeil J, Vincent WF. DOI 10.1111/1462-2920.15481

Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter. Nucleic acids research, 2021. Dion MB, Plante PL, Zufferey E, Shah SA, Corbeil J, Moineau S. DOI 10.1093/nar/gkab133