Jacques Couet

• Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (Affilié à l’Université Laval)
• Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (Reconnu FRQ - secteur santé)

• Nada Khribech, Doctorat en sciences cliniques et biomédicales
• Nicolas Le Bos, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Encadrements des 5 dernières années

• Audrey Morin-Grandmont, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Diwaba Carmel Teou, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Emylie-Ann Labbé, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Mohamed Lamine Aidara, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Sara-Ève Thibodeau, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Travaux de recherche des 5 dernières années

Cardiometabolic stress induces atrial myopathy in mice, characterized by structural remodelling, metabolic dysfunction, and incomplete transcriptional recovery. 2026. Jacques Couet, Diwaba Carmel Teou, Audrey Morin-Grandmont, Nicolas Le Bos, Thomas Le Bos, Emylie-Ann Labbé, Sara-Ève Thibodeau, Vincent Joseph, Marie Arsenault.

Cardiometabolic stress induces atrial myopathy in mice, characterized by structural remodelling, metabolic dysfunction, and incomplete transcriptional recovery 2026. Jacques Couet, Diwaba Carmel Teou, Audrey Morin-Grandmont, Nicolas Le Bos, Thomas Le Bos, Emylie-Ann Labbé, Sara-Ève Thibodeau, Vincent Joseph, Marie Arsenault. DOI 10.64898/2026.10.06.754161

White Adipose Tissue Contributes to Cardiac Homeostasis and Adaptation to Cardiometabolic Stress in a Sex- and Depot-Specific Manner Biomolecules, 2026. Sara-Ève Thibodeau, Nicolas Le Bos, Élisabeth Walsh-Wilkinson, Emylie-Ann Labbé, Audrey Morin-Grandmont, Emmy Trahan, Mathias Zakrzewski, Jacques Couet. DOI 10.3390/biom16091364

Sex-Dependent Cardiac Responses to β3-Adrenergic Receptor Activation in a Murine Model of Heart Failure with Preserved Ejection Fraction Biomedicines, 2026. Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Emylie-Ann Labbé, Diwaba Carmel Teou, Marie-Lune Legros, Jacques Couet. DOI 10.3390/biomedicines14071633

Sex-Specific Effects of the β3-Adrenergic Receptor Agonist Mirabegron in a Murine Two-Hit Heart Failure Model with Preserved Ejection Fraction 2025. Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Emylie-Ann Labbé, Jacques Couet. DOI 10.20944/preprints202509.2326.v1

Cold Exposure Exacerbates Cardiac Dysfunction in a Model of Heart Failure with Preserved Ejection Fraction in Male and Female C57Bl/6J Mice 2025. Sara-Ève Thibodeau, Marie-Lune Legros, Emylie-Ann Labbé, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Marie Arsenault, Alexandre Caron, Jacques Couet, Sarra Baji. DOI 10.20944/preprints202507.0593.v1

Relative contribution of correcting the diet and voluntary exercise to myocardial recovery in a two-hit murine model of heart failure with preserved ejection fraction American Journal of Physiology-Heart and Circulatory Physiology, 2025. Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Maude Chalifour, Pierre-Olivier Sirois, Juliette Leblanc, Audrey Morin-Grandmont, Marie Arsenault, Jacques Couet. DOI 10.1152/ajpheart.00092.2025

The Loss of Gonadal Hormones Has a Different Impact on Aging Female and Male Mice Submitted to Heart Failure-Inducing Metabolic Hypertensive Stress Cells, 2025. Diwaba Carmel Teou, Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Ann-Sarah Trudeau, Marie Arsenault, Jacques Couet. DOI 10.3390/cells14120870

Loss of Gonadal Hormones Has a Different Impact on Aging Female and Male Mice Submitted to a Heart Failure-Inducing Metabolic-Hypertensive Stress 2025. Diwaba Carmel Teou, Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Ann-Sarah Trudeau, Marie Arsenault, Jacques Couet. DOI 10.20944/preprints202505.0248.v1

Relative contributions of correcting the diet and voluntary exercise to myocardial recovery in a two-hit murine model of heart failure with preserved ejection fraction 2025. Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Maude Chalifour, Pierre-Olivier Sirois, Juliette Leblanc, Marie Arsenault, Jacques Couet. DOI 10.1101/2025.02.03.636256

Plasma and Myocardial miRNomes Similarities and Differences during Cardiac Remodelling and Reverse Remodelling in a Murine Model of Heart Failure with Preserved Ejection Fraction Biomolecules, 2024. Sara-Ève Thibodeau, Emylie-Ann Labbé, Élisabeth Walsh-Wilkinson, Audrey Morin-Grandmont, Marie Arsenault, Jacques Couet. DOI 10.3390/biom14080892

Cardiac reverse remodeling in a mouse model with many phenotypical features of heart failure with preserved ejection fraction: effects of modifying lifestyle American Journal of Physiology-Heart and Circulatory Physiology, 2024. Mohamed Lamine Aidara, Élisabeth Walsh-Wilkinson, Sara-Ève Thibodeau, Emylie-Ann Labbé, Audrey Morin-Grandmont, Geneviève Gagnon, Dominique K. Boudreau, Marie Arsenault, Yohan Bossé, Jacques Couët. DOI 10.1152/ajpheart.00462.2023

Age and sex hormones modulate left ventricle regional response to angiotensin II in male and female mice American Journal of Physiology-Heart and Circulatory Physiology, 2022. Élisabeth Walsh-Wilkinson, Mohamed Lamine Aidara, Audrey Morin-Grandmont, Sara-Ève Thibodeau, Juliette Gagnon, Mathieu Genest, Marie Arsenault, Jacques Couet. DOI 10.1152/ajpheart.00044.2022

Segmental analysis by speckle-tracking echocardiography of the left ventricle response to isoproterenol in male and female mice PeerJ, 2021. Elisabeth Walsh-Wilkinson, Marie Arsenault, Jacques Couet. DOI 10.7717/peerj.11085