Stéphane Bolduc

• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en organogenèse expérimentale
• Centre de recherche sur le cancer

Financements des 2 dernières années

• Elissa Elia, Doctorat en biologie cellulaire et moléculaire
• Laurence Carignan, Doctorat en biologie cellulaire et moléculaire
• Marilou Hardy, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Matisse Duval, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Rune Isherwood-Poor, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Yudaï Sahuc, Doctorat en biologie cellulaire et moléculaire

Encadrements des 5 dernières années

• Alexane Thibodeau, Stage postdoctoral en médecine
• Christophe Caneparo, Doctorat en biologie cellulaire et moléculaire
• David Brownell, Doctorat en biologie cellulaire et moléculaire
• Félix-Antoine Pellerin, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Jayson Josey Sueters, Stage postdoctoral en médecine
• Megan Richer, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Saeed Farzamfar, Stage postdoctoral en médecine

Travaux de recherche des 5 dernières années

Effects of Sex Hormones and Physical Environment on Epithelial Cell Identity and Plasticity in an Engineered Urethral Model Journal of Xenobiotics, 2026. Maxime Chaumery, Yudaï Sahuc, Stéphane Chabaud, Eric Philippe, Stéphane Bolduc. DOI 10.3390/jox16070211

From Bench to Operating Room: A Comparative Study of Tensile and Puncture Tests in Self-Assembled Constructs with Clinical Feedback Bioengineering, 2026. Elissa Elia, Marilou Hardy, Riham Mira Bensalem, Yudai Sahuc, Yannick Rioux, David Brownell, Stéphane Chabaud, Julie Fradette, Stéphane Bolduc. DOI 10.3390/bioengineering13091051

IGF-1 Increases Collagen Deposition by Dermal Fibroblasts: Applications for Tissue Engineering Cells, 2026. David Brownell, Alexane Thibodeau, Guillaume Locatelli, Aiden Smith, Megan Richer, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/cells15111023

Regenerative Medicine Approaches to Stress Urinary Incontinence Biomimetics, 2026. Alexane Thibodeau, Aiden Smith, Stéphane Chabaud, Geneviève Nadeau, Jean Ruel, Stéphane Bolduc. DOI 10.3390/biomimetics11050323

I-TEP: A Simple and Affordable Method to Measure Permeability in Reconstructed Tissues Combined with DAMO–TSC-Based Urea Assay Methods and Protocols, 2026. Yudaï Sahuc, Elissa Elia, Christophe Caneparo, Nathan Félix, Marilou Hardy, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/mps9030073

Impact of the Use of 2-Phospho-L Ascorbic Acid in the Production of Engineered Stromal Tissue for Regenerative Medicine Cells, 2025. Brownell, David, Carignan, Laurence, Alavi, Reza, Caneparo, Christophe, Labroy, Maxime, Galbraith, Todd, Chabaud, Stéphane, Berthod, François, Gibot, Laure, Bordeleau, François, Bolduc, Stéphane. DOI 10.3390/cells14141123

Description of the Human Penile Urethra Epithelium Medicina (Kaunas, Lithuania), 2025. Duval, Matisse, Brownell, David, Chabaud, Stéphane, Laungani, Alexis, Philippe, Eric, Bolduc, Stéphane. DOI 10.3390/medicina61050788

Correction of Significant Urethral Anomalies Using a Tissue-Engineered Human Urethral Substitute: Proof of Concept International journal of molecular sciences, 2025. Caneparo, Christophe, Elia, Elissa, Chabaud, Stéphane, Berthod, François, Fradette, Julie, Bolduc, Stéphane. DOI 10.3390/ijms26051825

Electrospun Polycaprolactone/Collagen Scaffolds Enhance Manipulability and Influence the Composition of Self-Assembled Extracellular Matrix Bioengineering (Basel, Switzerland), 2025. Farzamfar, Saeed, Chabaud, Stéphane, Fradette, Julie, Rioux, Yannick, Bolduc, Stéphane. DOI 10.3390/bioengineering12101077

Impact of antibiotic prophylaxis on urinary tract infection recurrence in children Rapid review Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2024. Potvin, Elyse, Adams, Kelsey, Barrieras, Diego, Bolduc, Stephane, Quach, Caroline. DOI 10.5489/cuaj.8678

Mimicking Urinary Tract Infections Caused by Uropathogenic Escherichia coli Using a Human Three-Dimensional Tissue Engineering Model Microorganisms, 2024. Pellerin, Félix-Antoine, Dufresne, Élodie, Chabaud, Stéphane, Orabi, Hazem, Bolduc, Stéphane. DOI 10.3390/microorganisms12112155

Navigating the Immunological Crossroads: Mesenchymal Stem/Stromal Cells as Architects of Inflammatory Harmony in Tissue-Engineered Constructs Bioengineering (Basel, Switzerland), 2024. Farzamfar, Saeed, Garcia, Luciana Melo, Rahmani, Mahya, Bolduc, Stephane. DOI 10.3390/bioengineering11050494

Impact of Endocrine Disruptors on the Genitourinary Tract Journal of xenobiotics, 2024. Caneparo, Christophe, Carignan, Laurence, Lonina, Elena, Goulet, Sarah-Maude, Pellerin, Felix-Antoine, Chabaud, Stéphane, Bordeleau, François, Bolduc, Stéphane, Pelletier, Martin. DOI 10.3390/jox14040099

Tissue Engineering for Penile Reconstruction Bioengineering (Basel, Switzerland), 2024. Elia, Elissa, Caneparo, Christophe, McMartin, Catherine, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/bioengineering11030230

Recreating heterogeneity of bladder cancer microenvironment to study its recurrences and progression Stem cell investigation, 2023. Bordeleau, François, Brownell, David, Chabaud, Stephane, Huot, Marc-Etienne, Bolduc, Stephane. DOI 10.21037/sci-2023-004

Extracellular Matrix-Based and Electrospun Scaffolding Systems for Vaginal Reconstruction Bioengineering (Basel, Switzerland), 2023. Farzamfar, Saeed, Elia, Elissa, Richer, Megan, Chabaud, Stéphane, Naji, Mohammad, Bolduc, Stéphane. DOI 10.3390/bioengineering10070790

Biological Macromolecule-Based Scaffolds for Urethra Reconstruction Biomolecules, 2023. Farzamfar, Saeed, Richer, Megan, Rahmani, Mahya, Naji, Mohammad, Aleahmad, Mehdi, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/biom13081167

Tridimensional cell culture of dermal fibroblasts promotes exosome-mediated secretion of extracellular matrix proteins Scientific reports, 2022. Clément, Vincent, Roy, Vincent, Paré, Bastien, Goulet, Cassandra R, Deschênes, Lydia Touzel, Berthod, François, Bolduc, Stéphane, Gros-Louis, François. DOI 10.1038/s41598-022-23433-0

Perception and satisfaction of patients after telemedicine urology consultations: A matched analysis with physicians' perspective Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2022. Turcotte, Bruno, Bélanger, Lynda, Blais, Anne-Sophie, Blouin, Annie-Claude, Bolduc, Stéphane, Bolduc-Mokhtar, Amélie, Bureau, Michel, Caumartin, Yves, Cloutier, Jonathan, Deschênes-Rompré, Marie-Pier, Dujardin, Thierry, Fradet, Yves, Gaudreau, Noémie, Lacombe, Louis, Moore, Katherine, Morin, Fannie, Nadeau, Geneviève, Paquet, Sophie, Simard, Francis, Simonyan, David, Soucy, Frédéric, Tiguert, Rabi, Toren, Paul, Lodde, Michele, Pouliot, Frédéric. DOI 10.5489/cuaj.7819

Comprehensive overview of the available pharmacotherapy for the treatment of non-neurogenic overactive bladder in children Expert opinion on pharmacotherapy, 2022. Ramsay, Sophie, Lapointe, Élisabeth, Bolduc, Stéphane. DOI 10.1080/14656566.2022.2072212

Engineered human organ-specific urethra as a functional substitute Scientific reports, 2022. Caneparo, Christophe, Chabaud, Stéphane, Fradette, Julie, Bolduc, Stéphane. DOI 10.1038/s41598-022-25311-1

First North American experience of propiverine use in children with overactive bladder Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2022. Lapointe, Élisabeth, Singbo, Narcisse, Naud, Élizabeth, Bolduc, Stéphane. DOI 10.5489/cuaj.7811

Cancer-Associated Fibroblasts in a 3D Engineered Tissue Model Induce Tumor-like Matrix Stiffening and EMT Transition Cancers, 2022. Millet, Martial, Bollmann, Enola, Ringuette Goulet, Cassandra, Bernard, Geneviève, Chabaud, Stéphane, Huot, Marc-Étienne, Pouliot, Frédéric, Bolduc, Stéphane, Bordeleau, François. DOI 10.3390/cancers14153810

Prospects and Challenges of Electrospun Cell and Drug Delivery Vehicles to Correct Urethral Stricture International journal of molecular sciences, 2022. Farzamfar, Saeed, Elia, Elissa, Chabaud, Stéphane, Naji, Mohammad, Bolduc, Stéphane. DOI 10.3390/ijms231810519

Bisphenols A and S Alter the Bioenergetics and Behaviours of Normal Urothelial and Bladder Cancer Cells Cancers, 2022. Pellerin, Ève, Pellerin, Félix-Antoine, Chabaud, Stéphane, Pouliot, Frédéric, Bolduc, Stéphane, Pelletier, Martin. DOI 10.3390/cancers14164011

Glucuronidated Metabolites of Bisphenols A and S Alter the Properties of Normal Urothelial and Bladder Cancer Cells International journal of molecular sciences, 2022. Pellerin, Ève, Pellerin, Félix-Antoine, Chabaud, Stéphane, Pouliot, Frédéric, Pelletier, Martin, Bolduc, Stéphane. DOI 10.3390/ijms232112859

Tissue Engineering for Gastrointestinal and Genitourinary Tracts International journal of molecular sciences, 2022. Elia, Elissa, Brownell, David, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/ijms24010009

Bladder cancer cell lines adapt their aggressiveness profile to oxygen tension Oncology letters, 2022. Chabaud, Stéphane, Pellerin, Ève, Caneparo, Christophe, Ringuette-Goulet, Cassandra, Pouliot, Frédéric, Bolduc, Stéphane. DOI 10.3892/ol.2022.13341

Tissue Engineering in Gynecology International journal of molecular sciences, 2022. Brownell, David, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/ijms232012319

UPEC Colonic-Virulence and Urovirulence Are Blunted by Proanthocyanidins-Rich Cranberry Extract Microbial Metabolites in a Gut Model and a 3D Tissue-Engineered Urothelium Microbiology spectrum, 2022. Roussel, Charlène, Chabaud, Stéphane, Lessard-Lord, Jacob, Cattero, Valentina, Pellerin, Félix-Antoine, Feutry, Perrine, Bochard, Valérie, Bolduc, Stéphane, Desjardins, Yves. DOI 10.1128/spectrum.02432-21

Evaluation of a Serum-Free Medium for Human Epithelial and Stromal Cell Culture International journal of molecular sciences, 2022. Caneparo, Christophe, Chabaud, Stéphane, Fradette, Julie, Bolduc, Stéphane. DOI 10.3390/ijms231710035

Considerations for the clinical use of stem cells in genitourinary regenerative medicine World journal of stem cells, 2021. Caneparo, Christophe, Sorroza-Martinez, Luis, Chabaud, Stéphane, Fradette, Julie, Bolduc, Stéphane. DOI 10.4252/wjsc.v13.i10.1480

Bisphenol A Alters the Energy Metabolism of Stromal Cells and Could Promote Bladder Cancer Progression Cancers, 2021. Pellerin, Ève, Chabaud, Stéphane, Pouliot, Frédéric, Pelletier, Martin, Bolduc, Stéphane. DOI 10.3390/cancers13215461

Immunocompetent Human 3D Organ-Specific Hormone-Responding Vaginal Mucosa Model of HIV-1 Infection Tissue engineering. Part C, Methods, 2021. Saba, Ingrid, Barat, Corinne, Chabaud, Stéphane, Reyjon, Nolan, Leclerc, Maude, Jakubowska, Weronika, Orabi, Hazem, Lachhab, Asmaa, Pelletier, Martin, Tremblay, Michel J, Bolduc, Stéphane. DOI 10.1089/ten.TEC.2020.0333

Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering Processes, 2021. Caneparo, Christophe, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/pr9030513

Case - Bilateral and recurrent pediatric cystic nephroma associated with DICER1 mutation Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2021. Caron, Cindy Pelletier, Turcotte, Bruno, Pelland-Marcotte, Marie-Claude, Schultz, Kris Ann P, Harvey, Isabelle, Bolduc, Stephane. DOI 10.5489/cuaj.6836

Heat-Inactivation of Fetal and Newborn Sera Did Not Impair the Expansion and Scaffold Engineering Potentials of Fibroblasts Bioengineering (Basel, Switzerland), 2021. Pellerin, Félix-Antoine, Caneparo, Christophe, Pellerin, Ève, Chabaud, Stéphane, Pelletier, Martin, Bolduc, Stéphane. DOI 10.3390/bioengineering8110184

Endocrine-disrupting effects of bisphenols on urological cancers Environmental research, 2021. Pellerin, Eve, Caneparo, Christophe, Chabaud, Stephane, Bolduc, Stephane, Pelletier, Martin. DOI 10.1016/j.envres.2020.110485

Genitourinary Tissue Engineering: Reconstruction and Research Models Bioengineering (Basel, Switzerland), 2021. Caneparo, Christophe, Brownell, David, Chabaud, Stéphane, Bolduc, Stéphane. DOI 10.3390/bioengineering8070099