Steve Lacroix

• Centre de recherche ARThrite
• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en arthrite
• Centre thématique de recherche en neurosciences

Financements des 2 dernières années

• Ana Boisvert, Doctorat en neurosciences
• Dominic Bélanger, Doctorat en médecine moléculaire
• Dominic Bélanger, Maîtrise en médecine moléculaire - avec mémoire
• Juliette Ferry, Doctorat en médecine moléculaire
• Maxime Kusik, Doctorat en médecine moléculaire

Encadrements des 5 dernières années

• Adrian Castellanos Molina, Doctorat en neurosciences
• Ana Boisvert, Maîtrise en neurosciences - avec mémoire
• Camille Cassandre Illiano, Doctorat en médecine moléculaire
• Felipe Da Gama Monteiro, Doctorat en médecine moléculaire
• Maxime Kusik, Maîtrise en médecine moléculaire - avec mémoire

Travaux de recherche des 5 dernières années

Activating systemic inflammation with lipopolysaccharide drives microglia-mediated degradation of perineuronal nets after cervical spinal cord injury in female rats. Experimental neurology, 2026. Cucarian J, Rakheja R, Scatterty KR, Armstrong E, Storvold S, Nguyen AT, Fenrich K, Burda JE, Lacroix S, Fouad K. DOI 10.1016/j.expneurol.2026.116068

Inflammatory Monocyte-Derived Macrophages Drive Pain via Their Production of Nerve Growth Factor after Peripheral Nerve Injury in Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2026. Kusik M, Paré A, Monteiro FDG, Nadeau S, Ferry J, Pineau I, Lessard M, Fortin N, Vallières N, Kerr B, Lacroix S. DOI 10.1523/jneurosci.1897-25.2026

Immobilized IgG-containing immune complexes require platelets to recruit neutrophils during inflammation. The Journal of clinical investigation, 2025. Bellio M, Allaeys I, Doré E, Vaillancourt M, Lévesque T, Monteil M, Vallières N, Desaulniers P, Bertrand N, Washington VA, Senis Y, Lacroix S, Fortin P, Belleannée C, Boilard E. DOI 10.1172/jci195987

Rapid and reliable image analysis pipeline for semi-automated quantification of CNS cell types in MATLAB Journal of Neuroscience Methods, 2025. Adrian Castellanos-Molina, Juliette Ferry, Ana Boisvert, Alexandre Chamberland, Nicolas Vallières, Steve Lacroix. DOI 10.1016/j.jneumeth.2025.110590

CSF1R ligands promote microglial proliferation but are not the sole regulators of developmental microglial proliferation Development, 2025. Brady P. Hammond, Sameera Zia, Eugene Hahn, Margarita Kapustina, Tristan Lange, Sarah Friesen, Rupali Manek, Kelly V. Lee, Adrian Castellanos-Molina, Floriane Bretheau, Mark S. Cembrowski, Bradley J. Kerr, Steve Lacroix, Jason R. Plemel. DOI 10.1242/dev.204610

Sleep-wake variation in body temperature regulates tau secretion and correlates with CSF and plasma tau Journal of Clinical Investigation, 2025. Geoffrey Canet, Felipe Da Gama Monteiro, Emma Rocaboy, Sofia Diego-Diaz, Boutheyna Khelaifia, Kelly Godbout, Aymane Lachhab, Jessica Kim, Daphne I. Valencia, Audrey Yin, Hau-Tieng Wu, Jordan Howell, Emily Blank, Francis Laliberté, Nadia Fortin, Emmanuelle Boscher, Parissa Fereydouni-Forouzandeh, Stéphanie Champagne, Isabelle Guisle, Sébastien S. Hébert, Vincent Pernet, Haiyan Liu, William Lu, Ludovic Debure, David M. Rapoport, Indu Ayappa, Andrew W. Varga, Ankit Parekh, Ricardo S. Osorio, Steve Lacroix, Mark P. Burns, Brendan P. Lucey, Esther M. Blessing, Emmanuel Planel. DOI 10.1172/jci182931

Constitutive DAMPs in CNS injury: From preclinical insights to clinical perspectives Brain, Behavior, and Immunity, 2024. Adrian Castellanos-Molina, Floriane Bretheau, Ana Boisvert, Dominic Bélanger, Steve Lacroix. DOI 10.1016/j.bbi.2024.07.047

Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner Nature Communications, 2024. Mohamed Reda Fazazi, Prenitha Mercy Ignatius Arokia Doss, Resel Pereira, Neva Fudge, Aryan Regmi, Charles Joly-Beauparlant, Irshad Akbar, Asmita Pradeep Yeola, Benoit Mailhot, Joanie Baillargeon, Philippe Grenier, Nicolas Bertrand, Steve Lacroix, Arnaud Droit, Craig S. Moore, Olga L. Rojas, Manu Rangachari. DOI 10.1038/s41467-024-49259-0

Understanding the role of the hematopoietic niche in Huntington's disease's phenotypic expression: in vivo evidence using a parabiosis model Neurobiology of Disease, 2023. Marie Rieux, Melanie Alpaugh, Shireen Salem, Alberto Siddu, Martine Saint-Pierre, Hélèna L. Denis, Heike Rohweder, Frank Herrmann, Chantal Bazenet, Steve Lacroix, Francesca Cicchetti. DOI 10.1016/j.nbd.2023.106091

The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury. Nature communications, 2022. Bretheau F, Castellanos-Molina A, Bélanger D, Kusik M, Mailhot B, Boisvert A, Vallières N, Lessard M, Gunzer M, Liu X, Boilard É, Quan N, Lacroix S. DOI 10.1038/s41467-022-33463-x

Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis Blood Advances, 2022. Audree Laroche, Denis Soulet, Marc Bazin, Tania Levesque, Isabelle Allaeys, Nicolas Vallières, Matthias Gunzer, Louis Flamand, Steve Lacroix, Eric Boilard. DOI 10.1182/bloodadvances.2021006728

Shedding a new light on Huntington’s disease: how blood can both propagate and ameliorate disease pathology Molecular Psychiatry, 2021. Marie Rieux, Melanie Alpaugh, Giacomo Sciacca, Martine Saint-Pierre, Maria Masnata, Hélèna L. Denis, Sébastien A. Lévesque, Frank Herrmann, Chantal Bazenet, Alexandre P. Garneau, Paul Isenring, Ray Truant, Abid Oueslati, Peter V. Gould, Anne Ast, Erich E. Wanker, Steve Lacroix, Francesca Cicchetti. DOI 10.1038/s41380-020-0787-4

The alarmin interleukin-1α triggers secondary degeneration through reactive astrocytes and endothelium after spinal cord injury 2021. Floriane Bretheau, Adrian Castellanos-Molina, Benoit Mailhot, Maxime Kusik, Dominic Belanger, Martine Lessard, Nicolas Vallières, Xiaoyu Liu, Ning Quan, Steve Lacroix. DOI 10.21203/rs.3.rs-580331/v1