Sylvie Breton

• Centre de recherche ARThrite
• Centre de recherche du CHU de Québec - Université Laval
• Centre de recherche en arthrite
• Centre de recherche en reproduction, développement et santé intergénérationnelle

Financements des 2 dernières années

• Aram Minas, Stage postdoctoral en médecine
• Emma Cavarocchi, Stage postdoctoral en médecine
• Jean-Philippe C Lavoie, Doctorat en microbiologie-immunologie
• Morgane Goux, Doctorat en médecine moléculaire
• Morgane Goux, Maîtrise en médecine moléculaire - avec mémoire

Encadrements des 5 dernières années

• Kéliane Brochu, Maîtrise en médecine moléculaire - avec mémoire
• Larissa Berloffa Belardin, Stage postdoctoral en médecine

Travaux de recherche des 5 dernières années

Urinary UDP-sugars provide actionable prediction of acute kidney injury in cardiac surgery patients American Journal of Physiology-Heart and Circulatory Physiology, 2026. Christine Légaré, Patrick Caron, Mohammad M. Al-Bataineh, Aisha Ford, David R. Emlet, Jessica Deslauriers, Dennis Brown, Chantal Guillemette, Siamak Mohammadi, Sylvie Breton. DOI 10.1152/ajpheart.00233.2026

<em>Urinary UDP-sugars provide actionable prediction of acute kidney injury in cardiac surgery patients</em> American Journal of Physiology-Heart and Circulatory Physiology, 2026. Christine Légaré, Patrick Caron, Mohammad M Al-bataineh, Aisha Ford, David R. Emlet, Jessica Deslauriers, Dennis Brown, Chantal Guillemette, Siamak Mohammadi, Sylvie Breton.

Role of Pannexin 1, P2X7, and CFTR in ATP Release and Autocrine Signaling by Principal Cells of the Epididymis Function, 2025. Kéliane Brochu, Aram Minas, Larissa Berloffa Belardin, Christine Légaré, Sylvie Breton. DOI 10.1093/function/zqaf016

Immunoregulatory mechanisms between epithelial clear cells and mononuclear phagocytes in the epididymis Andrology Y3 - 2023, 2023. Battistone, M. A., Elizagaray, M. L., Barrachina, F., Ottino, K., Mendelsohn, A. C., Breton, S.. DOI 10.1111/andr.13509

CX3CR1 deficiency leads to impairment of immune surveillance in the epididymis Cellular and Molecular Life Sciences, 2023. F. Barrachina, K. Ottino, L. J. Tu, R. J. Soberman, D. Brown, S. Breton, M. A. Battistone. DOI 10.1007/s00018-022-04664-w

Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists Journal of medicinal chemistry Y3 - 2023, 2023. Wen, Z., Pramanik, A., Lewicki, S. A., Jung, Y. H., Gao, Z. G., Randle, J. C. R., Cronin, C., Chen, Z., Giancotti, L. A., Whitehead, G. S., Liang, B. T., Breton, S., Salvemini, D., Cook, D. N., Jacobson, K. A.. DOI 10.1021/acs.jmedchem.3c00664

Expression of the pro-inflammatory P2Y14 receptor in the non-vasectomized and vasectomized human epididymis Andrology Y3 - 2022, 2022. Belardin, L. B., Légaré, C., Sullivan, R., Belleannée, C., Breton, S.. DOI 10.1111/andr.13284

The MAPK/ERK signaling pathway regulates the expression and localization of Cx43 in mouse proximal epididymis† Biology of reproduction Y3 -, 2022. Kim, B., Breton, S.. DOI 10.1093/biolre/ioac034

Unexpected Participation of Intercalated Cells in Renal Inflammation and Acute Kidney Injury Nephron Y3 - 2021, 2022. Breton, S., Battistone, M. A.. DOI 10.1159/000519265

A liquid chromatography-mass spectrometry assay for the quantification of nucleotide sugars in human plasma and urine specimens and its clinical application Journal of chromatography. A Y3 - 2022, 2022. Caron, P., Nguyen Van Long, F., Rouleau, M., Bujold, E., Fortin, P., Mohammadi, S., Lévesque, É, Breton, S., Guillemette, C.. DOI 10.1016/j.chroma.2022.463296

Purinergic signaling in the male reproductive tract Frontiers in endocrinology Y3 - 2022, 2022. Belardin, L. B., Brochu, K., Légaré, C., Battistone, M. A., Breton, S.. DOI 10.3389/fendo.2022.1049511

Sperm acquire epididymis-derived proteins through epididymosomes Human reproduction (Oxford, England) Y3 -, 2022. Barrachina, F., Battistone, M. A., Castillo, J., Mallofré, C., Jodar, M., Breton, S., Oliva, R.. DOI 10.1093/humrep/deac015

Commentary: Novel preoperative predictors of acute kidney injury following cardiac surgery: Is it a game changer? The Journal of thoracic and cardiovascular surgery Y3 - 2021, 2021. Breton, S., Kalavrouziotis, D., Mohammadi, S.. DOI 10.1016/j.jtcvs.2021.04.055

Urinary UDP-Glucose as a Novel Actionable Biomarker of Dehydration-Induced Acute Kidney Injury Annals of Nutrition and Metabolism, 2021. Maria Agustina Battistone, Alexandra C. Mendelsohn, Dennis Brown, Sylvie Breton. DOI 10.1159/000520566

Caput Ligation Renders Immature Mouse Sperm Motile and Capable to Undergo cAMP-Dependent Phosphorylation International journal of molecular sciences Y3 - 2021, 2021. Tourzani, D. A., Battistone, M. A., Salicioni, A. M., Breton, S., Visconti, P. E., Gervasi, M. G.. DOI 10.3390/ijms221910241