Vanessa Houde

• Centre Nutrition, santé et société
• Groupe de recherche en écologie buccale

Financements des 2 dernières années

• Johana Romina Naja, Stage postdoctoral en médecine dentaire
• Luisa Bakhbukh, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Marianne Bouvette, Maîtrise en sciences cliniques et biomédicales - avec mémoire
• Nathalia Fernanda Sczesny, Doctorat en génie des matériaux et de la métallurgie

Encadrements des 5 dernières années

• Laurie Pelletier, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Leyla Desparois, Maîtrise en microbiologie - avec mémoire
• Naomie Larrivée, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Sarah Lafleur, Maîtrise en sciences dentaires - parodontie - avec mémoire
• Xavier Minne, Maîtrise en microbiologie - avec mémoire
• Zied Ferjaoui, Stage postdoctoral en médecine dentaire

Travaux de recherche des 5 dernières années

Manual Polishing of Ti6Al4V Produces Minimal Changes in Oral Bacterial Adhesion and Osteogenic Cell Behavior Archives of Oral Biology, 2026. Leyla Desparois, Pascale Chevallier, Diego Mantovani, Vanessa P. Houde. DOI 10.1016/j.archoralbio.2026.106690

Metabolic-microbial crosstalk drives inflammasome activation: fasn and palmitoylation mediate palmitate-Porphyromonas gingivalis synergy in macrophage-like cells Scientific Reports, 2026. Vanessa P. Houde, Mégane St-Georges, Fatiha Chandad. DOI 10.1038/s41598-026-69877-6

A Plasma-Functionalized ECM Platform for Intraoral Inflammation Control: Comparative Effects of Hyaluronic Acid and N-Acetyl-L-Cysteine on Oral Keratinocyte Response Polymers, 2026. Pedro U. Muñoz-González, Pascale Chevallier, Leyla Desparois, Sylvie Louise Avon, Fatiha Chandad, Diego Mantovani, Vanessa P. Houde. DOI 10.3390/polym18080977

Structure-Driven Bioactivity of Chitosan-Agarose-Gelatin Hydrogels Functionalized with Tannic Acid-Cu2+/Sr2+ Complexes. ACS applied materials & interfaces, 2026. Wekwejt M, Chevallier P, Desgagne F, Rodriguez-Fernandez S, Cournoyer E, Houde VP, Mantovani D. DOI 10.1021/acsami.6c01091

Polydopamine-mediated zinc-doped calcium-deficient hydroxyapatite coating on Ti–6Al–4V: a multifunctional strategy for enhancing osteogenesis and bactericidity Materials Advances, 2026. Mariana Pires Figueiredo, Pascale Chevallier, Francesco Copes, Elliott Cournoyer, Vanessa P. Houde, Diego Mantovani. DOI 10.1039/D6MA00233A

In vitro modulation of proinflammatory and proteolytic activities of Porphyromonas gingivalis by selected lactobacilli Journal of Oral Microbiology, 2025. Johana R. Naja, Leyla Desparois, Elvira M. Hebert, Maria Elena Fátima Nader, Lucila Saavedra, Carlos J. Minahk, Vanessa P. Houde. DOI 10.1080/20002297.2025.2469894

Supragingival Microbiota Alterations in Individuals With Sleep Bruxism: A Pilot Study Journal of Oral Rehabilitation, 2025. Athénaïs Collard, Alban Mathieu, Paolo Landa, Annik Pelletier, Gilles J. Lavigne, Arnaud Droit, Nelly Huynh, Vanessa P. Houde. DOI 10.1111/joor.13983

ACLY inhibition promotes tumour immunity and suppresses liver cancer. Nature, 2025. Gautam J, Wu J, Lally JSV, McNicol JD, Fayyazi R, Ahmadi E, Oniciu DC, Heaton S, Newton RS, Rehal S, Bhattacharya D, Di Pastena F, Nguyen B, Valvano CM, Townsend LK, Banskota S, Batchuluun B, Jabile MJT, Payne A, Lu J, Desjardins EM, Kubota N, Tsakiridis EE, Mistry B, Aganostopoulos A, Houde V, Dansercoer A, Verschueren KHG, Savvides SN, Hammill JA, Bezverbnaya K, Muti P, Tsakiridis T, Dai W, Jiang L, Hoshida Y, Larché M, Bramson JL, Friedman SL, Verstraete K, Wang D, Steinberg GR. DOI 10.1038/s41586-025-09297-0

Regulation of PPARγ2 Stability and Activity by SHP-1. Molecular and cellular biology, 2024. Kumar A, Laborit Labrada B, Lavallée-Bourget MH, Forest MP, Schwab M, Bellmann K, Houde V, Beauchemin N, Laplante M, Marette A. DOI 10.1080/10985549.2024.2354959

Fluorocarbon Plasma-Polymerized Layer Increases the Release Time of Silver Ions and the Antibacterial Activity of Silver-Based Coatings Nanomaterials, 2024. Linda Bonilla-Gameros, Pascale Chevallier, Xavier Delvaux, L. Astrid Yáñez-Hernández, Laurent Houssiau, Xavier Minne, Vanessa P. Houde, Andranik Sarkissian, Diego Mantovani. DOI 10.3390/nano14070609

Rebaudioside D decreases adiposity and hepatic lipid accumulation in a mouse model of obesity. Scientific reports, 2024. Morissette A, de Wouters d'Oplinter A, Andre DM, Lavoie M, Marcotte B, Varin TV, Trottier J, Pilon G, Pelletier M, Cani PD, Barbier O, Houde VP, Marette A. DOI 10.1038/s41598-024-53587-y

The metabolic benefits of substituting sucrose for maple syrup are associated with a shift in carbohydrate digestion and gut microbiota composition in high-fat high-sucrose diet-fed mice. American journal of physiology. Endocrinology and metabolism, 2023. Morissette A, André DM, Agrinier AL, Varin TV, Pilon G, Flamand N, Houde VP, Marette A. DOI 10.1152/ajpendo.00065.2023

Porphyromonas gingivalis under palmitate-induced obesogenic microenvironment modulates the inflammatory transcriptional signature of macrophage-like cells PLOS ONE, 2023. Xavier Minne, Joanna Mbuya Malaïka Mutombo, Fatiha Chandad, Roberto D. Fanganiello, Vanessa P. Houde. DOI 10.1371/journal.pone.0288009

Probiotic Supplementation, Hepatic Fibrosis, and the Microbiota Profile in Patients with Nonalcoholic Steatohepatitis: A Randomized Controlled Trial. The Journal of nutrition, 2023. Escouto GS, Port GZ, Tovo CV, Fernandes SA, Peres A, Dorneles GP, Houde VP, Varin TV, Pilon G, Marette A, Buss C. DOI 10.1016/j.tjnut.2023.05.019

Multi-Omics Data Integration Reveals Key Variables Contributing to Subgingival Microbiome Dysbiosis-Induced Inflammatory Response in a Hyperglycemic Microenvironment International Journal of Molecular Sciences, 2023. Sarah Lafleur, Antoine Bodein, Joanna Mbuya Malaïka Mutombo, Alban Mathieu, Charles Joly Beauparlant, Xavier Minne, Fatiha Chandad, Arnaud Droit, Vanessa P. Houde. DOI 10.3390/ijms24108832

Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity. Gut, 2022. Daoust L, Choi BS, Agrinier AL, Varin TV, Ouellette A, Mitchell PL, Samson N, Pilon G, Levy E, Desjardins Y, Laplante M, Anhê FF, Houde VP, Marette A. DOI 10.1136/gutjnl-2021-326475

Bioactivity of mackerel peptides on obesity and insulin resistance, an in-vivo study Food Bioscience, 2022. Soheila Abachi Hokmabadinazhad, Jean-Philippe Songpadith, Vanessa P. Houde, Geneviève Pilon, Ismail Fliss, André Marette, Laurent Bazinet, Lucie Beaulieu. DOI 10.1016/j.fbio.2022.101641

The Concentration of Organic Acids in Cranberry Juice Modulates the Gut Microbiota in Mice International Journal of Molecular Sciences, 2021. Valentine Renaud, Vanessa P. Houde, Geneviève Pilon, Thibault V. Varin, Cyril Roblet, André Marette, Yvan Boutin, Laurent Bazinet. DOI 10.3390/ijms222111537

Salsalate reduces atherosclerosis through AMPKβ1 in mice. Molecular metabolism, 2021. Day EA, Ford RJ, Smith BK, Houde VP, Stypa S, Rehal S, Lhotak S, Kemp BE, Trigatti BL, Werstuck GH, Austin RC, Fullerton MD, Steinberg GR. DOI 10.1016/j.molmet.2021.101321

Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice Nature Communications, 2021. Béatrice S.-Y. Choi, Noëmie Daniel, Vanessa P. Houde, Adia Ouellette, Bruno Marcotte, Thibault V. Varin, Cécile Vors, Perrine Feutry, Olga Ilkayeva, Marcus Ståhlman, Philippe St-Pierre, Fredrik Bäckhed, Angelo Tremblay, Phillip J. White, André Marette. DOI 10.1038/s41467-021-23782-w

Purple grumixama anthocyanins (Eugenia brasiliensis Lam.) attenuate obesity and insulin resistance in high-fat diet mice. Food & function, 2021. Teixeira LL , Pilon G , Coutinho CP , Dudonné S , Dube P , Houde V , Desjardins Y , Lajolo FM , Marette A , Hassimotto NMA . DOI 10.1039/d0fo03245j