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André Tchernof

Professeur titulaire
(418) 656-4141, poste 46349
andre.tchernof@criucpq.ulaval.ca
Université Laval, I.U.C.P.Q.
2725, chemin Sainte-Foy
Local 2614

Unité de rattachement — Faculté
Sciences de l'agriculture et de l'alimentation

Affiliations
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Centre de recherche du CHU de Québec - Université Laval

Chaire de recherche en chirurgie bariatrique et métabolique
Programme: Chaires de recherche sans organismes subventionnaires
Organisme(s) subventionnaire(s): Johnson & Johnson inc
Établissement tête: Université Laval
Du 1 mai 2009 au 31 décembre 2022

Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer
Programme: Volet Projet: Concours pilotes
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 juillet 2016 au 30 septembre 2024

Adipocyte dedifferentiation in the ceiling culture system: regulators of cell matrix remodelling
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC)
Établissement tête: Université Laval
Du 1 avril 2017 au 31 mars 2023

Institut sur la nutrition et les aliments fonctionnels (INAF)
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes, Université McGill, Université du Québec à Rimouski, Université de Sherbrooke
Établissement tête: Université Laval
Du 1 avril 2017 au 31 mars 2024

Chaire de recherche en chirurgie bariatrique et métabolique
Programme: Chaires de recherche sans organismes subventionnaires
Organisme(s) subventionnaire(s): Fondation de l'Université Laval
Établissement tête: Université Laval
Du 1 janvier 2018 au 31 décembre 2022

Omega-3 fatty acids in the prevention of breast cancer: role of obesity-related markers in breast tissues
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 octobre 2018 au 30 septembre 2026

Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3
Programme: Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 novembre 2019 au 31 octobre 2024

Dissecting host-microbiome modifiers of type 2 diabetes risk
Programme: Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 novembre 2019 au 31 octobre 2024

Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.2
Programme: Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 novembre 2019 au 31 octobre 2024

Predicting weight loss and metabolic improvements after bariatric surgery through a novel genetic and epigenetic score
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 avril 2020 au 31 mars 2024

3alpha-hydroxysteroid dehydrogenase type 3 as a modulator of human adipose tissue function and distribution
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 avril 2020 au 31 mars 2024

Réseau de recherche sur la santé cardiométabolique, le diabète et l'obésité (CMDO U. Laval))
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Établissement tête: Université Laval
Du 1 avril 2021 au 31 mars 2024

Intervention intensive sur le mode de vie chez les patients avec un diabète de type 2 avancé insulino-traité : un projet pilote
Programme: Subventions pour la recherche
Organisme(s) subventionnaire(s): Diabète Québec
Établissement tête: Université Laval
Du 1 juillet 2021 au 30 juin 2023

A transcriptome- and proteome-wide association study of non-alcoholic fatty liver disease
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 octobre 2021 au 30 septembre 2024

Management of sleeve gastrectomy failure using single-anastomosis metabolic surgery
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 octobre 2021 au 30 septembre 2026

Breast adipocyte hypertrophy: a novel biomarker to predict breast cancer survival
Programme: Subvention de fonctionnement
Organisme(s) subventionnaire(s): American Institute for Cancer Research
Établissement tête: Université Laval
Du 1 janvier 2021 au 31 mars 2023

Training platform in diabetes, obesity and cardiometabolic health
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 janvier 2021 au 31 décembre 2027

Creation and animation of a dynamic community of patient partners and citizens for a Canada-wide training and mentoring platform: myROaD
Programme: Patient Engagement Enhancement Activities on the Health Research Training Platform Pilot
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 mars 2022 au 28 février 2023

Bone and Muscle Health Following Sleeve Gastrectomy in Men, Premenopausal and Postmenopausal Women
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 avril 2022 au 31 mars 2027

Caractérisation et prise en charge de l'obésité
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Établissement tête: Université Laval
Du 1 juillet 2022 au 30 juin 2023

Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Établissement tête: Université Laval
Du 1 juillet 2022 au 30 juin 2027

Subventions des 5 dernières années

Determinants of metabolic recovery following bariatric surgery in individuals with type 2 diabetes mellitus
Programme: Subvention d'équipe : Soins bariatriques
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada, Fonds de recherche du Québec - Santé
Établissement tête: Université Laval
Du 1 avril 2014 au 31 mars 2021

Animation scientifique - Axe obésité, diabète de type et et métabolisme
Organisme(s) subventionnaire(s): Fondation de l'Institut universitaire de cardiologie et de pneumologie de Québec, Novo Nordisk Canada, Inc., Eli Lilly Canada, Inc.
Établissement tête: Université Laval
Du 1 avril 2017 au 31 mars 2021

DNA methylation-based determinants of obesity-related metabolic complications and improvements after bariatric surgery
Programme: Subventions de recherche
Organisme(s) subventionnaire(s): Fondation des maladies du coeur et de l'AVC du Canada
Établissement tête: Université Laval
Du 1 juillet 2017 au 30 juin 2021

Évaluation du programme CHANGE pour les personnes à risque de développer un cancer du sein
Organisme(s) subventionnaire(s): Fondation du cancer du sein du Québec
Établissement tête: Université Laval
Du 1 décembre 2018 au 15 juillet 2022

Rôle des microARNs dans le métabolisme des acides gras alimentaires du diabète de type 2
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Établissement tête: Université de Sherbrooke
Du 1 avril 2020 au 31 mars 2021

Impact de saines habitudes de vie sur la condition métabolique de femmes ayant été atteintes d'un cancer du sein
Programme: Accélération Québec (MITACS/MEIE)
Organisme(s) subventionnaire(s): MITACS Inc.
Établissement tête: Université Laval
Du 1 juin 2020 au 30 juin 2022

Associations Between the Changes in Gut Microbiota and Bone and Muscle Outcomes After Sleeve Gastrectomy
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Établissement tête: Université Laval
Du 1 avril 2021 au 31 mars 2022

Encadrements terminés dans les 5 dernières années

  • Luis Fernando Sorroza Martinez, Maîtrise en sciences cliniques et biomédicales - avec mémoire
  • Jennifer Labrecque, Maîtrise en nutrition - avec mémoire
  • Geneviève Gagnon, Maîtrise en nutrition - avec mémoire
  • Sofia Laforest, Doctorat en nutrition
  • Publications des 5 dernières années

    Revisional Surgery: Second-Stage Duodenal Switch Laparoscopic Sleeve Gastrectomy, 2021/01/05. Laurent Biertho, Simon Marceau, Stéfane Lebel, François Julien, André Tchernof. DOI 10.1007/978-3-030-57373-7_55

    Impact of weight loss on brain age: Improved brain health following bariatric surgery NeuroImage, 2022/10. Yashar Zeighami, Mahsa Dadar, Justine Daoust, Mélissa Pelletier, Laurent Biertho, Léonie Bouvet-Bouchard, Stephanie Fulton, André Tchernof, Alain Dagher, Denis Richard, Alan Evans, Andréanne Michaud. DOI 10.1016/j.neuroimage.2022.119415

    Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity Amino Acids, 2022/07/09. Ina Maltais-Payette, Jinchu Vijay, Marie-Michelle Simon, Jacques Corbeil, Francis Brière, Elin Grundberg, André Tchernof. DOI 10.1007/s00726-022-03181-1

    Associations of Biomarkers of Inflammation and Breast Cancer in the Breast Adipose Tissue of Women with Combined Measures of Adiposity Journal of Obesity, 2021. Chang, S.-L., Tchernof, A., Durocher, F., Diorio, C.. DOI 10.1155/2021/3620147

    AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants Molecular and Cellular Endocrinology, 2021. Ostinelli, G., Vijay, J., Vohl, M.-C., Grundberg, E., Tchernof, A.. DOI 10.1016/j.mce.2021.111220

    Association between visceral adiposity index, binge eating behavior, and grey matter density in caudal anterior cingulate cortex in severe obesity Brain Sciences, 2021. Iceta, S., Dadar, M., Daoust, J., Scovronec, A., Leblanc, V., Pelletier, M., Biertho, L., Tchernof, A., Bégin, C., Michaud, A.. DOI 10.3390/brainsci11091158

    Associations between markers of mammary adipose tissue dysfunction and breast cancer prognostic factors International Journal of Obesity, 2021. Laforest, S., Ennour-Idrissi, K., Ouellette, G., Gauthier, M.-F., Michaud, A., Durocher, F., Tchernof, A., Diorio, C.. DOI 10.1038/s41366-020-00676-3

    IGFBP-2 partly mediates the early metabolic improvements caused by bariatric surgery Cell Reports Medicine, 2021. Faramia, J., Hao, Z., Mumphrey, M.B., Townsend, R.L., Miard, S., Carreau, A.-M., Nadeau, M., Frisch, F., Baraboi, E.-D., Grenier-Larouche, T., Noll, C., Li, M., Biertho, L., Marceau, S., Hould, F.-S., Lebel, S., Morrison, C.D., Münzberg, H., Richard, D., Carpentier, A.C., Tchernof, A., Berthoud, H.-R., Picard, F.. DOI 10.1016/j.xcrm.2021.100248

    Bacterial postbiotics as promising tools to mitigate cardiometabolic diseases Journal of Lipid and Atherosclerosis, 2021. Anhê, F.F., Jensen, B.A.H., Perazza, L.R., Tchernof, A., Schertzer, J.D., Marette, A.. DOI 10.12997/jla.2021.10.2.123

    Consistent gut bacterial and short-chain fatty acid signatures in hypoabsorptive bariatric surgeries correlate with metabolic benefits in rats International Journal of Obesity, 2021. Mukorako, P., Lemoine, N., Biertho, L., Lebel, S., Roy, M.-C., Plamondon, J., Tchernof, A., Varin, T.V., Anhê, F.F., St-Pierre, D.H., Marette, A., Richard, D.. DOI 10.1038/s41366-021-00973-5

    Deciphering the Association Between Hypothalamus-Pituitary-Adrenal Axis Activity and Obesity: A Meta-Analysis Obesity, 2021. Ostinelli, G., Scovronec, A., Iceta, S., Ouellette, A.-S., Lemieux, S., Biertho, L., Bégin, C., Michaud, A., Tchernof, A.. DOI 10.1002/oby.23125

    Spontaneous neural activity changes after bariatric surgery: A resting-state fMRI study bioRxiv, 2021. Zeighami, Y., Iceta, S., Dadar, M., Pelletier, M., Nadeau, M., Biertho, L., Lafortune, A., Tchernof, A., Fulton, S., Evans, A., Richard, D., Dagher, A., Michaud, A.. DOI 10.1101/2021.04.01.437973

    Liver enhancer signature and regulatory network of non-alcoholic steatohepatitis resistance in humans with obesity bioRxiv, 2021. Hung, Y.-H., Sritharan, R., Vohl, M.-C., Ilkayeva, O., Biertho, L., Tchernof, A., White, P.J., Sethupathy, P.. DOI 10.1101/2021.08.20.457162

    Management of Obesity in Cardiovascular Practice: JACC Focus Seminar Journal of the American College of Cardiology, 2021. Després, J.-P., Carpentier, A.C., Tchernof, A., Neeland, I.J., Poirier, P.. DOI 10.1016/j.jacc.2021.05.035

    Spontaneous neural activity changes after bariatric surgery: A resting-state fMRI study NeuroImage, 2021. Zeighami, Y., Iceta, S., Dadar, M., Pelletier, M., Nadeau, M., Biertho, L., Lafortune, A., Tchernof, A., Fulton, S., Evans, A., Richard, D., Dagher, A., Michaud, A.. DOI 10.1016/j.neuroimage.2021.118419

    Bariatric surgery rapidly decreases cardiac dietary fatty acid partitioning and hepatic insulin resistance through increased intra-abdominal adipose tissue storage and reduced spillover in type 2 diabetes Diabetes, 2020. Carreau, A.-M., Noll, C., Blondin, D.P., Frisch, F., Nadeau, M., Pelletier, M., Phoenix, S., Cunnane, S.C., Guérin, B., Turcotte, E.E., Lebel, S., Biertho, L., Tchernof, A., Carpentier, A.C.. DOI 10.2337/db19-0773

    Obesity Phenotypes, Diabetes, and Cardiovascular Diseases Circulation Research, 2020/05. Marie-Eve Piché, André Tchernof, Jean-Pierre Després. DOI 10.1161/circresaha.120.316101

    Acute and Chronic Impact of Biliopancreatic Diversion with Duodenal Switch Surgery on Plasma Lipoprotein(a) Levels in Patients with Severe Obesity Obesity Surgery, 2020. Després, A.-A., Piché, M.-E., Auclair, A., Biertho, L., Marceau, S., Hould, F.-S., Biron, S., Lebel, S., Lescelleur, O., Julien, F., Martin, J., Tchernof, A., Mathieu, P., Poirier, P., Arsenault, B.J.. DOI 10.1007/s11695-020-04450-2

    Association between changes in bioactive osteocalcin and glucose homeostasis after biliopancreatic diversion Endocrine, 2020. Turcotte, A.-F., Grenier-Larouche, T., Lacombe, J., Carreau, A.-M., Carpentier, A.C., Mac-Way, F., Tchernof, A., Richard, D., Biertho, L., Lebel, S., Marceau, S., Ferron, M., Gagnon, C.. DOI 10.1007/s12020-020-02340-2

    Measurement of bioactive osteocalcin in humans using a novel immunoassay reveals association with glucose metabolism and β-cell function American Journal of Physiology - Endocrinology and Metabolism, 2020. Lacombe, J., Rifai, O.A., Loter, L., Moran, T., Turcotte, A.-F., Grenier-Larouche, T., Tchernof, A., Biertho, L., Carpentier, A.C., Prud'homme, D., Rabasa-Lhoret, R., Karsenty, G., Gagnon, C., Jiang, W., Ferron, M.. DOI 10.1152/ajpendo.00321.2019

    Characterization of a Coproduct from the Sea Cucumber Cucumaria frondosa and Its Effects on Visceral Adipocyte Size in Male Wistar Rats Marine drugs, 2020. Ramalho, A., Leblanc, N., Fortin, M.-G., Marette, A., Tchernof, A., Jacques, H.. DOI 10.3390/md18110530

    Estrogens and glucocorticoids in mammary adipose tissue: Relationships with body mass index and breast cancer features Journal of Clinical Endocrinology and Metabolism, 2020. Laforest, S., Pelletier, M., Denver, N., Poirier, B., Nguyen, S., Walker, B.R., Durocher, F., Homer, N.Z.M., Diorio, C., Andrew, R., Tchernof, A.. DOI 10.1210/clinem/dgz268

    IGFBP-2 Partly Mediates the Early Metabolic Improvements Caused by Bariatric Surgery SSRN, 2020. Faramia, J., Hao, Z., Mumphrey, M.B., Townsend, R.L., Miard, S., Carreau, A.-M., Nadeau, M., Frisch, F., Baraboi, E.-D., Grenier-Larouche, T., Noll, C., Li, M., Biertho, L., Marceau, S., Hould, F.-S., Lebel, S., Morrison, C.D., Münzberg, H., Richard, D., Carpentier, A.C., Tchernof, A., Berthoud, H.-R., Picard, F.. DOI 10.2139/ssrn.3667141

    Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types Nature Metabolism, 2020. Vijay, J., Gauthier, M.-F., Biswell, R.L., Louiselle, D.A., Johnston, J.J., Cheung, W.A., Belden, B., Pramatarova, A., Biertho, L., Gibson, M., Simon, M.-M., Djambazian, H., Staffa, A., Bourque, G., Laitinen, A., Nystedt, J., Vohl, M.-C., Fraser, J.D., Pastinen, T., Tchernof, A., Grundberg, E.. DOI 10.1038/s42255-019-0152-6

    Metabolic adaptations after bariatric surgery: adipokines, myokines and hepatokines Current Opinion in Pharmacology, 2020. Faramia, J., Ostinelli, G., Drolet-Labelle, V., Picard, F., Tchernof, A.. DOI 10.1016/j.coph.2020.06.005

    Neighbourhood effects on obesity: Scoping review of time-varying outcomes and exposures in longitudinal designs BMJ Open, 2020. Letarte, L., Pomerleau, S., Tchernof, A., Biertho, L., Waygood, E.O.D., Lebel, A.. DOI 10.1136/bmjopen-2019-034690

    Neuroanatomical changes in white and grey matter after sleeve gastrectomy NeuroImage, 2020. Michaud, A., Dadar, M., Pelletier, M., Zeighami, Y., Garcia-Garcia, I., Iceta, S., Yau, Y., Nadeau, M., Marceau, S., Biertho, L., Tchernof, A., Collins, D.L., Richard, D., Dagher, A.. DOI 10.1016/j.neuroimage.2020.116696

    Acute and chronic effect of bariatric surgery on circulating autotaxin levels Physiological Reports, 2019. Bourgeois, R., Piché, M.-E., Auclair, A., Grenier-Larouche, T., Mitchell, P.L., Poirier, P., Biertho, L., Marceau, S., Hould, F.-S., Biron, S., Lebel, S., Lescelleur, O., Julien, F., Martin, J., Tchernof, A., Mathieu, P., Carpentier, A.C., Arsenault, B.J.. DOI 10.14814/phy2.14004

    Ten-year remission rates in insulin-treated type 2 diabetes after biliopancreatic diversion with duodenal switch Surgery for Obesity and Related Diseases, 2020. Kapeluto, J.E., Tchernof, A., Masckauchan, D., Biron, S., Marceau, S., Hould, F.-S., Lebel, S., Lescelleur, O., Julien, F., Biertho, L.. DOI 10.1016/j.soard.2020.06.052

    The Modified Yale Food Addiction Scale 2.0: Validation Among Non-Clinical and Clinical French-Speaking Samples and Comparison With the Full Yale Food Addiction Scale 2.0 Frontiers in Psychiatry, 2020. Brunault, P., Berthoz, S., Gearhardt, A.N., Gierski, F., Kaladjian, A., Bertin, E., Tchernof, A., Biertho, L., de Luca, A., Hankard, R., Courtois, R., Ballon, N., Benzerouk, F., Bégin, C.. DOI 10.3389/fpsyt.2020.480671

    Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity Nature Metabolism, 2020. Anhê, F.F., Jensen, B.A.H., Varin, T.V., Servant, F., Van Blerk, S., Richard, D., Marceau, S., Surette, M., Biertho, L., Lelouvier, B., Schertzer, J.D., Tchernof, A., Marette, A.. DOI 10.1038/s42255-020-0178-9

    Characterization and visualization of the liposecretion process taking place during ceiling culture of human mature adipocytes Journal of Cellular Physiology, 2019. Côté, J.A., Gauthier, M.-F., Ostinelli, G., Brochu, D., Bellmann, K., Marette, A., Julien, F., Lebel, S., Tchernof, A.. DOI 10.1002/jcp.27931

    Assessing the impact of the diet on cardiometabolic outcomes: are multiple measurements post-intervention necessary? European Journal of Clinical Nutrition, 2019. Allaire, J., Talbot, D., Couture, P., Tchernof, A., Jones, P.J.H., Kris-Etherton, P., West, S.G., Connelly, P.W., Jenkins, D.J.A., Lamarche, B.. DOI 10.1038/s41430-018-0257-0

    Association between lifestyle habits and adiposity values among children exposed and unexposed to gestational diabetes mellitus in utero Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 2019. Bélanger, M., Dugas, C., Perron, J., Ruchat, S.-M., Weisnagel, S.J., Marc, I., Tchernof, A., Robitaille, J.. DOI 10.1016/j.dsx.2019.07.053

    Body mass index is associated with epigenetic age acceleration in the visceral adipose tissue of subjects with severe obesity Clinical Epigenetics, 2019. De Toro-Martín, J., Guénard, F., Tchernof, A., Hould, F.-S., Lebel, S., Julien, F., Marceau, S., Vohl, M.-C.. DOI 10.1186/s13148-019-0754-6

    Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements Nature Communications, 2019. Allum, F., Hedman, Å.K., Shao, X., Cheung, W.A., Vijay, J., Guénard, F., Kwan, T., Simon, M.-M., Ge, B., Moura, C., Boulier, E., Rönnblom, L., Bernatsky, S., Lathrop, M., McCarthy, M.I., Deloukas, P., Tchernof, A., Pastinen, T., Vohl, M.-C., Grundberg, E.. DOI 10.1038/s41467-019-09184-z

    Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk Nutrition, Metabolism and Cardiovascular Diseases, 2019. Maltais-Payette, I., Allam-Ndoul, B., Pérusse, L., Vohl, M.-C., Tchernof, A.. DOI 10.1016/j.numecd.2019.08.015

    Comparing the serum TAG response to high-dose supplementation of either DHA or EPA among individuals with increased cardiovascular risk: The ComparED study British Journal of Nutrition, 2019. Allaire, J., Vors, C., Harris, W.S., Jackson, K.H., Tchernof, A., Couture, P., Lamarche, B.. DOI 10.1017/S0007114519000552

    Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome (Genome Biology (2017) 18 (50) DOI: 10.1186/s13059-017-1173-7) Genome Biology, 2019. Cheung, W.A., Shao, X., Morin, A., Siroux, V., Kwan, T., Ge, B., Aïssi, D., Chen, L., Vasquez, L., Allum, F., Guénard, F., Bouzigon, E., Simon, M.-M., Boulier, E., Redensek, A., Watt, S., Datta, A., Clarke, L., Flicek, P., Mead, D., Paul, D.S., Beck, S., Bourque, G., Lathrop, M., Tchernof, A., Vohl, M.-C., Demenais, F., Pin, I., Downes, K., Stunnenberg, H.G., Soranzo, N., Pastinen, T., Grundberg, E.. DOI 10.1186/s13059-019-1702-7

    Interleukin-1β and prostaglandin-synthesizing enzymes as modulators of human omental and subcutaneous adipose tissue function Prostaglandins Leukotrienes and Essential Fatty Acids, 2019. Labrecque, J., Michaud, A., Gauthier, M.-F., Pelletier, M., Julien, F., Bouvet-Bouchard, L., Tchernof, A.. DOI 10.1016/j.plefa.2018.11.015

    Effects of 6-month Vitamin D supplementation on insulin sensitivity and secretion: A randomised, placebo-controlled trial European Journal of Endocrinology, 2019. Lemieux, P., John Weisnagel, S., Caron, A.Z., Julien, A.-S., Morisset, A.-S., Carreau, A.-M., Poirier, J., Tchernof, A., Robitaille, J., Bergeron, J., Marette, A., Vohl, M.-C., Gagnon, C.. DOI 10.1530/EJE-19-0156

    Effects of Biliopancreatic Diversion on Bone Turnover Markers and Association with Hormonal Factors in Patients with Severe Obesity Obesity Surgery, 2019. Turcotte, A.-F., Grenier-Larouche, T., Ung, R.-V., Simonyan, D., Carreau, A.-M., Carpentier, A.C., Mac-Way, F., Michou, L., Tchernof, A., Biertho, L., Lebel, S., Marceau, S., Gagnon, C.. DOI 10.1007/s11695-018-3617-x

    Focus on dedifferentiated adipocytes: characteristics, mechanisms, and possible applications Cell and Tissue Research, 2019. Côté, J.A., Ostinelli, G., Gauthier, M.-F., Lacasse, A., Tchernof, A.. DOI 10.1007/s00441-019-03061-3

    The Passing of Dr. Fernand Labrie (1937–2019): The legacy of excellence in science Journal of Steroid Biochemistry and Molecular Biology, 2019. Tchernof, A., Lin, S.X., Luu-The, V., Simard, J.. DOI 10.1016/j.jsbmb.2019.02.005

    Is a healthy diet associated with lower anthropometric and glycemic alterations in predisposed children born from mothers with gestational diabetes mellitus? Nutrients, 2019. Dugas, C., Bélanger, M., Perron, J., John Weisnagel, S., Tchernof, A., Marc, I., Robitaille, J.. DOI 10.3390/nu11030570

    Neuroanatomical changes in white and grey matter after sleeve gastrectomy bioRxiv, 2019. Michaud, A., Dadar, M., Pelletier, M., Zeighami, Y., Garcia-Garcia, I., Yau, Y., Nadeau, M., Marceau, S., Biertho, L., Tchernof, A., Louis Collins, D., Richard, D., Dagher, A., Bégin, C., Biertho, L., Bouvier, M., Biron, S., Cani, P., Carpentier, A., Dagher, A., Dubé, F., Fergusson, A., Fulton, S., Hould, F.S., Julien, F., Kieffer, T., Laferrère, B., Lafortune, A., Lebel, S., Lescelleur, O., Levy, E., Marette, A., Marceau, S., Michaud, A., Picard, F., Poirier, P., Richard, D., Schertzer, J., Tchernof, A., Vohl, M.C.. DOI 10.1101/678284

    Simultaneous quantification of estrogens and glucocorticoids in human adipose tissue by liquid-chromatography-tandem mass spectrometry Journal of Steroid Biochemistry and Molecular Biology, 2019. Laforest, S., Pelletier, M., Denver, N., Poirier, B., Nguyen, S., Walker, B.R., Durocher, F., Homer, N.Z.M., Diorio, C., Tchernof, A., Andrew, R.. DOI 10.1016/j.jsbmb.2019.105476

    Association of prenatal exposure to gestational diabetes with offspring body composition and regional body fat distribution Clinical obesity, 2018. Kearney, M., Perron, J., Marc, I., Weisnagel, S.J., Tchernof, A., Robitaille, J.. DOI 10.1111/cob.12237

    The deubiquitinating enzyme USP19 modulates adipogenesis and potentiates high-fat-diet-induced obesity and glucose intolerance in mice Diabetologia, 2019. Coyne, E.S., Bédard, N., Gong, Y.J., Faraj, M., Tchernof, A., Wing, S.S.. DOI 10.1007/s00125-018-4754-4

    UCP1 expression–associated gene signatures of human epicardial adipose tissue JCI Insight, 2019. Chechi, K., Vijay, J., Voisine, P., Mathieu, P., Bossé, Y., Tchernof, A., Grundberg, E., Richard, D.. DOI 10.1172/jci.insight.123618

    Androgens and the regulation of adiposity and body fat distribution in humans Comprehensive Physiology, 2018. Tchernof, A., Brochu, D., Maltais-Payette, I., Mansour, M.F., Marchand, G.B., Carreau, A.-M., Kapeluto, J.. DOI 10.1002/CPHY.C170009

    Early life nutrition, glycemic and anthropometric profiles of children exposed to gestational diabetes mellitus in utero Early Human Development, 2018. Dugas, C., Kearney, M., Mercier, R., Perron, J., Tchernof, A., Marc, I., Weisnagel, S.J., Robitaille, J.. DOI 10.1016/j.earlhumdev.2018.02.004

    Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations Nutrition and Metabolism, 2018. Maltais-Payette, I., Boulet, M.-M., Prehn, C., Adamski, J., Tchernof, A.. DOI 10.1186/s12986-018-0316-5

    Circulating steroid levels as correlates of adipose tissue phenotype in premenopausal women Hormone Molecular Biology and Clinical Investigation, 2018. Marchand, G.B., Carreau, A.-M., Laforest, S., Côté, J.-A., Daris, M., Cianflone, K., Prehn, C., Adamski, J., Tchernof, A.. DOI 10.1515/hmbci-2017-0082

    Depot-Specific Adipose Tissue Metabolite Profiles and Corresponding Changes Following Aerobic Exercise Frontiers in Endocrinology, 2018. Brennan, A.M., Tchernof, A., Gerszten, R.E., Cowan, T.E., Ross, R.. DOI 10.3389/fendo.2018.00759

    Histomorphometric analyses of human adipose tissues using intact, flash-frozen samples Histochemistry and Cell Biology, 2018. Laforest, S., Pelletier, M., Michaud, A., Daris, M., Descamps, J., Soulet, D., Jensen, M.D., Tchernof, A.. DOI 10.1007/s00418-018-1635-3

    Establishing a food addiction diagnosis using the Yale Food Addiction Scale: A closer look at the clinically significant distress/functional impairment criterion Appetite, 2018. Ouellette, A.-S., Rodrigue, C., Lemieux, S., Tchernof, A., Biertho, L., Bégin, C.. DOI 10.1016/j.appet.2018.06.031

    Executive functioning and psychological symptoms in food addiction: a study among individuals with severe obesity Eating and Weight Disorders, 2018. Rodrigue, C., Ouellette, A.-S., Lemieux, S., Tchernof, A., Biertho, L., Bégin, C.. DOI 10.1007/s40519-018-0530-1

    High-dose DHA has more profound effects on LDL-related features than high-dose EPA: The ComparED study Journal of Clinical Endocrinology and Metabolism, 2018. Allaire, J., Vors, C., Tremblay, A.J., Marin, J., Charest, A., Tchernof, A., Couture, P., Lamarche, B.. DOI 10.1210/jc.2017-02745

    Longitudinal designs to study neighbourhood effects on the development of obesity: A scoping review protocol BMJ Open, 2018. Letarte, L., Lebel, A., Waygood, E.O.D., Tchernof, A., Biertho, L.. DOI 10.1136/bmjopen-2017-017704

    Impact of experimentally induced cognitive dietary restraint on eating behavior traits, appetite sensations, and markers of stress during energy restriction in overweight/obese women Journal of Obesity, 2018. Morin, I., Bégin, C., Maltais-Giguère, J., Bédard, A., Tchernof, A., Lemieux, S.. DOI 10.1155/2018/4259389

    Increased body fat mass explains the positive association between circulating estradiol and insulin resistance in postmenopausal women American Journal of Physiology - Endocrinology and Metabolism, 2018. Marchand, G.B., Carreau, A.-M., Weisnagel, S.J., Bergeron, J., Labrie, F., Lemieux, S., Tchernof, A.. DOI 10.1152/AJPENDO.00293.2017

    Liver and plasma lipid changes induced by cyclic fatty acid monomers from heated vegetable oil in the rat Food Science and Nutrition, 2018. Mboma, J., Leblanc, N., Wan, S., Jacobs, R.L., Tchernof, A., Dubé, P., Angers, P., Jacques, H.. DOI 10.1002/fsn3.766

    Second-stage duodenal switch for sleeve gastrectomy failure: A matched controlled trial Surgery for Obesity and Related Diseases, 2018. Biertho, L., Thériault, C., Bouvet, L., Marceau, S., Hould, F.-S., Lebel, S., Julien, F., Tchernof, A.. DOI 10.1016/j.soard.2018.05.008

    Plasma Steroids are Not Associated with Resting and Exercise Blood Pressure International Journal of Sports Medicine, 2018. He, Z., Rankinen, T., Leon, A.S., Skinner, J., Tchernof, A., Bouchard, C.. DOI 10.1055/a-0660-0121

    Plasma steroids, body composition, and fat distribution: effects of age, sex, and exercise training International Journal of Obesity, 2018. He, Z., Rankinen, T., Leon, A.S., Skinner, J.S., Tchernof, A., Bouchard, C.. DOI 10.1038/s41366-018-0033-1

    Polygenic risk score for predicting weight loss after bariatric surgery JCI insight, 2018. de Toro-Martín, J., Guénard, F., Tchernof, A., Pérusse, L., Marceau, S., Vohl, M.-C.. DOI 10.1172/jci.insight.122011

    An examination of the mechanisms and personality traits underlying food addiction among individuals with severe obesity awaiting bariatric surgery Eating and Weight Disorders, 2017. Ouellette, A.-S., Rodrigue, C., Lemieux, S., Tchernof, A., Biertho, L., Bégin, C.. DOI 10.1007/s40519-017-0440-7

    Sex Differences in Body Fat Distribution Adipose Tissue Biology, 2017/04/04. Mohamed Fouad Mansour, Chon-Wai Jeremy Chan, Sofia Laforest, Alain Veilleux, André Tchernof. DOI 10.1007/978-3-319-52031-5_8

    Acute and chronic impact of bariatric surgery on plasma LDL cholesterol and PCSK9 levels in patients with severe obesity Journal of Clinical Endocrinology and Metabolism, 2017. Boyer, M., Piché, M.-E., Auclair, A., Grenier-Larouche, T., Biertho, L., Marceau, S., Hould, F.-S., Biron, S., Lebel, S., Lescelleur, O., Julien, F., Martin, J., Tchernof, A., Carpentier, A.C., Poirier, P., Arsenault, B.J.. DOI 10.1210/jc.2017-00699

    Adiposity, breast density, and breast cancer risk: Epidemiological and biological considerations European Journal of Cancer Prevention, 2017. Soguel, L., Durocher, F., Tchernof, A., Diorio, C.. DOI 10.1097/CEJ.0000000000000310

    Fatty Acid Metabolic Remodeling During Type 2 Diabetes Remission After Bariatric Surgery Diabetes, 2017. Grenier-Larouche, T., Carreau, A.-M., Geloën, A., Frisch, F., Biertho, L., Marceau, S., Lebel, S., Hould, F.-S., Richard, D., Tchernof, A., Carpentier, A.C.. DOI 10.2337/db17-0414

    Biliopancreatic diversion with duodenal switch leads to better postprandial glucose level and beta cell function than sleeve gastrectomy in individuals with type 2 diabetes very early after surgery Metabolism: Clinical and Experimental, 2017. Michaud, A., Grenier-Larouche, T., Caron-Dorval, D., Marceau, S., Biertho, L., Simard, S., Richard, D., Tchernof, A., Carpentier, A.C.. DOI 10.1016/j.metabol.2017.06.005

    Comparative analysis of three human adipocyte size measurement methods and their relevance for cardiometabolic risk Obesity, 2017. Laforest, S., Michaud, A., Paris, G., Pelletier, M., Vidal, H., Géloën, A., Tchernof, A.. DOI 10.1002/oby.21697

    Diet as a potential modulator of body fat distribution Nutrition and Cardiometabolic Health, 2017. Laforest, S., Marchand, G.B., Tchernof, A.. DOI 10.1201/9781315119410

    Impact of Bariatric Surgery on White Adipose Tissue Inflammation Canadian Journal of Diabetes, 2017. Labrecque, J., Laforest, S., Michaud, A., Biertho, L., Tchernof, A.. DOI 10.1016/j.jcjd.2016.12.003

    Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome Genome Biology, 2017. Cheung, W.A., Shao, X., Morin, A., Siroux, V., Kwan, T., Ge, B., Aïssi, D., Chen, L., Vasquez, L., Allum, F., Guénard, F., Bouzigon, E., Simon, M.-M., Boulier, E., Redensek, A., Watt, S., Datta, A., Clarke, L., Flicek, P., Mead, D., Paul, D.S., Beck, S., Bourque, G., Lathrop, M., Tchernof, A., Vohl, M.-C., Demenais, F., Pin, I., Downes, K., Stunnenberg, H.G., Soranzo, N., Pastinen, T., Grundberg, E.. DOI 10.1186/s13059-017-1173-7

    Genetic regulation of differentially methylated genes in visceral adipose tissue of severely obese men discordant for the metabolic syndrome Translational Research, 2017. Guénard, F., Tchernof, A., Deshaies, Y., Biron, S., Lescelleur, O., Biertho, L., Marceau, S., Pérusse, L., Vohl, M.-C.. DOI 10.1016/j.trsl.2017.01.002

    Identification of the ectoenzyme CD38 as a marker of committed preadipocytes International Journal of Obesity, 2017. Carrière, A., Jeanson, Y., Côté, J.-A., Dromard, C., Galinier, A., Menzel, S., Barreau, C., Dupuis-Coronas, S., Arnaud, E., Girousse, A., Cuminetti, V., Paupert, J., Cousin, B., Sengenes, C., Koch-Nolte, F., Tchernof, A., Casteilla, L.. DOI 10.1038/ijo.2017.140

    Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes BMC Systems Biology, 2017. Chénard, T., Guénard, F., Vohl, M.-C., Carpentier, A., Tchernof, A., Najmanovich, R.J.. DOI 10.1186/s12918-017-0438-9

    Inflammatory gene expression in whole blood cells after EPA vs. DHA supplementation: Results from the ComparED study Atherosclerosis, 2017. Vors, C., Allaire, J., Marin, J., Lépine, M.-C., Charest, A., Tchernof, A., Couture, P., Lamarche, B.. DOI 10.1016/j.atherosclerosis.2017.01.025

    Plasma steroids and cardiorespiratory fitness response to regular exercise Research and Perspectives in Endocrine Interactions, 2017. He, Z., Rankinen, T., Leon, A.S., Skinner, J.S., Tchernof, A., Bouchard, C.. DOI 10.1007/978-3-319-72790-5_3

    Postnatal Prevention of Childhood Obesity in Offspring Prenatally Exposed to Gestational Diabetes mellitus: Where Are We Now? Obesity Facts, 2017. Dugas, C., Perron, J., Kearney, M., Mercier, R., Tchernof, A., Marc, I., Weisnagel, S.J., Robitaille, J.. DOI 10.1159/000477407

    Supplementation with high-dose docosahexaenoic acid increases the Omega-3 Index more than high-dose eicosapentaenoic acid Prostaglandins Leukotrienes and Essential Fatty Acids, 2017. Allaire, J., Harris, W.S., Vors, C., Charest, A., Marin, J., Jackson, K.H., Tchernof, A., Couture, P., Lamarche, B.. DOI 10.1016/j.plefa.2017.03.008

    Retraction to: Effects of the Menopause Transition on Body Fatness and Body Fat Distribution (Obesity Research, (1998), 6, 3, (246-254), 10.1002/j.1550-8528.1998.tb00344.x) Obesity, 2017. Tchernof, A., Poehlman, E.T.. DOI 10.1002/oby.21856

    Role of the TGF-β pathway in dedifferentiation of human mature adipocytes FEBS Open Bio, 2017. Côté, J.A., Lessard, J., Pelletier, M., Marceau, S., Lescelleur, O., Fradette, J., Tchernof, A.. DOI 10.1002/2211-5463.12250

    Sex differences in body fat distribution Adipose Tissue Biology: Second Edition, 2017. Mansour, M.F., Chan, C.-W.J., Laforest, S., Veilleux, A., Tchernof, A.. DOI 10.1007/978-3-319-52031-5_8

    What Is Known About the Correlates and Impact of Excess Skin After Bariatric Surgery: a Scoping Review Obesity Surgery, 2017. Baillot, A., Brais-Dussault, E., Bastin, A., Cyr, C., Brunet, J., Aimé, A., Romain, A.J., Langlois, M.-F., Bouchard, S., Tchernof, A., Rabasa-Lhoret, R., Garneau, P.-Y., Bernard, P.. DOI 10.1007/s11695-017-2814-3

    Surgery for Diabetes: Clinical and Mechanistic Aspects Canadian Journal of Diabetes, 2017. Kapeluto, J., Tchernof, A., Biertho, L.. DOI 10.1016/j.jcjd.2017.05.008

    Temporal Changes in Gene Expression Profile during Mature Adipocyte Dedifferentiation International Journal of Genomics, 2017. Côté, J.A., Guénard, F., Lessard, J., Lapointe, M., Biron, S., Vohl, M.-C., Tchernof, A.. DOI 10.1155/2017/5149362

    The Rapidly Evolving Landscape of Bariatric Surgery Canadian Journal of Diabetes, 2017. Tchernof, A., Weisnagel, S.J.. DOI 10.1016/j.jcjd.2017.05.010


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