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Louis Bessette

Médecin clinicien enseignant agrégé
Pavillon Ferdinand-Vandry
1050, avenue de la Médecine
Local 4211

Unité de rattachement — Faculté

Centre de recherche du CHU de Québec - Université Laval
Centre de recherche en arthrite

Financements des 2 dernières années

Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis
Organisme(s) subventionnaire(s): Société de l'arthrite du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 janvier 2020 au 31 décembre 2022

Publications des 5 dernières années

Treatment with Upadacitinib in Active Psoriatic Arthritis: Efficacy and Safety Data of the First 192 Patients from the UPJOINT Study, a Multicentre, Observational Study in Clinical Practice Rheumatology and Therapy, 2023/12. Stephanie G. Werner, Xenofon Baraliakos, Sabine Reckert, Martin Bohl-Bühler, Marie-Claude Laliberté, Tanya Girard, Katharina Jeromin, Nikola Baschuk, Björn Fritz, Louis Bessette, Axel J. Hueber. DOI 10.1007/s40744-023-00589-3

Effectiveness of a treat-to-target strategy in patients with moderate to severely active rheumatoid arthritis treated with abatacept. Arthritis research & therapy, 2023/09/28. Bessette L, Haraoui B, Rampakakis E, Dembowy J, Trépanier MO, Pope J. DOI 10.1186/s13075-023-03151-2

Late onset leflunomide-induced cutaneous ulcers in a seronegative arthritis patient: A case report. SAGE open medical case reports, 2023/08/25. Couture-Lapointe C, Grenier PO, Bessette L, Veillette H. DOI 10.1177/2050313x231195480

Does the Type of Failure and the Choice of the Second Biologic Influence Response and Persistence on Medication in Rheumatoid Arthritis? Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2023/08/24. Bessette L, Movahedi M, Reed G, Kremer JM, Kane K, Keystone E. DOI 10.1097/rhu.0000000000002013

“From Where I Stand”: using multiple anchors yields different benchmarks for meaningful improvement and worsening in the rheumatoid arthritis flare questionnaire (RA-FQ) Quality of Life Research, 2023/05. Susan J. Bartlett, Vivian P. Bykerk, Orit Schieir, Marie-France Valois, Janet E. Pope, Gilles Boire, Carol Hitchon, Glen Hazlewood, Louis Bessette, Edward Keystone, Carter Thorne, Diane Tin, Clifton O. Bingham, III, M Baron, I Colmegna, S Fallavollita, D Haaland, B Haraoui, S Jamal, R Joshi, B Nair, P Panopoulos, L Rubin, E Villeneuve, M Zummer. DOI 10.1007/s11136-022-03227-7

Drs. Bessette and Kinch reply The Journal of Rheumatology, 2023/04. Louis Bessette, Cassandra D. Kinch. DOI 10.3899/jrheum.220909

Impact of Tofacitinib on Components of the ACR Response Criteria: Post Hoc Analysis of Phase III and Phase IIIb/IV Trials The Journal of Rheumatology, 2022/06. Louis Bessette, Eduardo Mysler, Cassandra D. Kinch, Kenneth Kwok, Tatjana Lukic, Phu Vinh On, Ronald F. van Vollenhoven. DOI 10.3899/jrheum.210707

Reply Arthritis and Rheumatology, 2022. Fatima, S., Schieir, O., Keystone, E.C., Valois, M.F., Bartlett, S.J., Bessette, L., Boire, G., Hazlewood, G., Hitchon, C., Tin, D., Thorne, C., Bykerk, V.P., Pope, J.E.. DOI 10.1002/art.41918

A Bridge Too Far? Real‐World Practice Patterns of Early Glucocorticoid Use in the Canadian Early Arthritis Cohort ACR Open Rheumatology, 2022/01. Kathleen M. Andersen, Orit Schieir, Marie‐France Valois, Susan J. Bartlett, Louis Bessette, Gilles Boire, Boulos Haraoui, Glen Hazlewood, Carol Hitchon, Edward C. Keystone, Janet Pope, Diane Tin, J Carter Throne, Vivian P. Bykerk. DOI 10.1002/acr2.11334

Long-term safety and efficacy of upadacitinib or adalimumab in patients with rheumatoid arthritis: results through 3 years from the SELECT-COMPARE study RMD Open, 2022. Fleischmann, R., Mysler, E., Bessette, L., Peterfy, C.G., Durez, P., Tanaka, Y., Swierkot, J., Khan, N., Bu, X., Li, Y., Song, I.-H.. DOI 10.1136/rmdopen-2021-002012

Predictors of Influenza Vaccination in Early Rheumatoid Arthritis 2017-2021: Results From the Canadian Early Arthritis Cohort ACR Open Rheumatology, 2022. Ta, Viviane, Schieir, Orit, Valois, Marie-France, Colmegna, Ines, Hitchon, Carol, Bessette, Louis, Hazlewood, Glen, Thorne, Carter, Pope, Janet, Boire, Gilles, Tin, Diane, Keystone, Edward C., Bykerk, Vivian P., Bartlett, Susan J.. DOI 10.1002/ACR2.11427

Prediction of Osteoporotic Fractures in Elderly Individuals: A Derivation and Internal Validation Study Using Healthcare Administrative Data Journal of Bone and Mineral Research, 2021/12. Claudia Beaudoin, Sonia Jean, Lynne Moore, Philippe Gamache, Louis Bessette, Louis‐Georges Ste‐Marie, Jacques P. Brown. DOI 10.1002/jbmr.4438

Expectations and educational needs of rheumatologists, rheumatology fellows and patients in the field of precision medicine in Canada, a quantitative cross-sectional and descriptive study BMC Rheumatology, 2021. Ruel-Gagné, S., Simonyan, D., Légaré, J., Bessette, L., Fortin, P.R., Lacaille, D., Dogba, M.J., Michou, L.. DOI 10.1186/s41927-021-00222-2

Expression of the myeloid inhibitory receptor CLEC12A correlates with disease activity and cytokines in early rheumatoid arthritis Scientific Reports, 2021. Vaillancourt, M., Desaulniers, P., Paré, G., Pagé, N., Lachhab, A., Kerever, A., Julien, A.-S., Amiable, N., Pelletier, M., Tessier, P.A., Bessette, L., Michou, L., Fortin, P.R., Fernandes, M.J.. DOI 10.1038/s41598-021-90631-7

Health Assessment Questionnaire at One Year Predicts All-Cause Mortality in Patients With Early Rheumatoid Arthritis Arthritis and Rheumatology, 2021. Fatima, S., Schieir, O., Valois, M.F., Bartlett, S.J., Bessette, L., Boire, G., Hazlewood, G., Hitchon, C., Keystone, E.C., Tin, D., Thorne, C., Bykerk, V.P., Pope, J.E., Baron, M., Bessette, L., Boire, G., Bykerk, V., Colmegna, I., Fallavollita, S., Haaland, D., Haraoui, P., Hazlewood, G., Hitchon, C., Jamal, S., Joshi, R., Keystone, E., Nair, B., Panopoulos, P., Pope, J., Rubin, L., Thorne, C., Villeneuve, E., Zummer, M.. DOI 10.1002/art.41513

Frequency and Duration of Early Non-serious Adverse Events in Patients with Rheumatoid Arthritis and Psoriatic Arthritis Treated with Tofacitinib Rheumatology and Therapy, 2021. Dikranian, A., Gold, D., Bessette, L., Nash, P., Azevedo, V.F., Wang, L., Woolcott, J., Shapiro, A.B., Szumski, A., Fleishaker, D., Wollenhaupt, J.. DOI 10.1007/s40744-021-00405-w

Improvements in Fatigue Lag Behind Disease Remission in Early Rheumatoid Arthritis: Results From the Canadian Early Arthritis Cohort Arthritis and Rheumatology, 2021. Holdren, M., Schieir, O., Bartlett, S.J., Bessette, L., Boire, G., Hazlewood, G., Hitchon, C.A., Keystone, E., Tin, D., Thorne, C., Bykerk, V.P., Pope, J.E.. DOI 10.1002/art.41499

Safety profile of upadacitinib in rheumatoid arthritis: Integrated analysis from the SELECT phase III clinical programme Annals of the Rheumatic Diseases, 2021. Cohen, S.B., Van Vollenhoven, R.F., Winthrop, K.L., Zerbini, C.A.F., Tanaka, Y., Bessette, L., Zhang, Y., Khan, N., Hendrickson, B., Enejosa, J.V., Burmester, G.R.. DOI 10.1136/annrheumdis-2020-218510

Sustainability of Response Between Upadacitinib and Adalimumab in Patients with Rheumatoid Arthritis: Results Through 3 Years from the SELECT-COMPARE Trial Arthritis & Rheumatology, 2021. Nash, Peter, Kavanaugh, Arthur, Buch, Maya, Combe, Bernard, Bessette, Louis, Song, In-Ho, Shaw, Tim, Song, Yanna, Suboticki, Jessica, Fleischmann, Roy.

Switching between janus kinase inhibitor upadacitinib and adalimumab following insufficient response: Efficacy and safety in patients with rheumatoid arthritis Annals of the Rheumatic Diseases, 2021. Fleischmann, R.M., Blanco, R., Hall, S., Thomson, G.T.D., Van Den Bosch, F.E., Zerbini, C., Bessette, L., Enejosa, J., Li, Y., Song, Y., Demasi, R., Song, I.-H.. DOI 10.1136/annrheumdis-2020-218412

An international, multicentre, double-blind, randomized study (DISSCO): effect of diacerein vs celecoxib on symptoms in knee osteoarthritis Rheumatology (United Kingdom), 2020. Pelletier, J.-P., Raynauld, J.-P., Dorais, M., Bessette, L., Dokoupilova, E., Morin, F., Pavelka, K., Paiement, P., Martel-Pelletier, J.. DOI 10.1093/rheumatology/keaa072

Major stressors in the year prior to disease onset affects RA characteristics at baseline and 12 months: results from the Canadian Early Arthritis Cohort (CATCH) Quality of Life Research, 2020. Andersen, Nicole, Schieir, Orit, Valois, Marie-France, Andersen, Kathleen, Boires, Gilles, Bessette, Louis, Tin, Diane, Thorne, Carter, Pope, Janet, Hitchon, Carol, Hazlewood, Glen, Keystone, Edward, Bykerk, Vivian, Bartlett, Susan.

Onset and maintenance of efficacy of subcutaneous tanezumab in patients with moderate to severe osteoarthritis of the knee or hip: A 16-week dose-titration study Seminars in Arthritis and Rheumatism, 2020. Schnitzer, T.J., Khan, A., Bessette, L., Davignon, I., Brown, M.T., Pixton, G., Prucka, W.R., Tive, L., Viktrup, L., West, C.R.. DOI 10.1016/j.semarthrit.2020.03.004

What are the rheumatology educational preferences of family medicine residents? A descriptive study Clinical Rheumatology, 2020. Lagacé, S., Julien, A.-S., Rheault, C., Bessette, L., Michou, L.. DOI 10.1007/s10067-020-05018-2

APPLICATION OF TREAT TO TARGET AND IMPACT OF SUSTAINED LOW DISEASE ACTIVITY OR REMISSION ON FUNCTION IN RHEUMATOID ARTHRITIS PATIENTS Internal Medicine Journal, 2020. Bessette, Louis, Keystone, Ed, Rahman, Proton, Anderson, Keltie, Rampakakis, Emmanouil, Lehman, Allen J., Rachich, Meagan, Nantel, Francois, Asin-Milan, Odalis.

An open-label randomized controlled trial of DMARD withdrawal in RA patients achieving therapeutic response with certolizumab pegol combined with DMARDs Rheumatology (United Kingdom), 2020. Pope, J., Rampakakis, E., Vaillancourt, J., Bessette, L., Lazovskis, J., Haraoui, B., Sampalis, J.S.. DOI 10.1093/rheumatology/kez470

Experience with tofacitinib in Canada: Patient characteristics and treatment patterns in rheumatoid arthritis over 3 years Rheumatology (United Kingdom), 2020. Pope, J., Bessette, L., Jones, N., Fallon, L., Woolcott, J., Gruben, D., Crooks, M., Gold, D., Haraoui, B.. DOI 10.1093/rheumatology/kez324

Impact of Ixekizumab on Work Productivity in Patients with Ankylosing Spondylitis: Results from the COAST-V and COAST-W Trials at 52 Weeks Rheumatology and Therapy, 2020. Marzo-Ortega, H., Mease, P.J., Rahman, P., Navarro-Compán, V., Strand, V., Dougados, M., Combe, B., Wei, J.C.-C., Baraliakos, X., Hunter, T., Sandoval, D., Li, X., Zhu, B., Bessette, L., Deodhar, A.. DOI 10.1007/s40744-020-00225-4

Treatment Strategies in Early Rheumatoid Arthritis Methotrexate Management: Results From a Prospective Cohort Arthritis Care and Research, 2020. Moura, C.S., Schieir, O., Valois, M.-F., Thorne, C., Bartlett, S.J., Pope, J.E., Hitchon, C.A., Boire, G., Haraoui, B., Hazlewood, G.S., Keystone, E.C., Tin, D., Bykerk, V.P., Bernatsky, S., Baron, M., Bessette, L., Colmegna, I., Fallavollita, S., Haaland, D., Haraoui, P., Jamal, S., Jamal, S., Joshi, R., Nair, B., Panopoulos, P., Penney, C., Rubin, L., Villeneuve, E., Zummer, M.. DOI 10.1002/acr.23927

APPLICATION OF TREAT TO TARGET AND IMPACT OF SUSTAINED LOW DISEASE ACTIVITY OR REMISSION ON FUNCTION IN ANKYLOSING SPONDYLITIS PATIENTS Internal Medicine Journal, 2020. Maksymowych, Walter, Inman, Robert, Bessette, Louis, Rahman, Proton, Rampakakis, Emmanouil, Asin-Milan, Odalis, Rachich, Meagan, Nantel, Francois, Lehman, Allen J..

Differences in fracture prevalence and in bone mineral density between Chinese and White Canadians: the Canadian Multicentre Osteoporosis Study (CaMos) Archives of Osteoporosis, 2020. Morin, S.N., Berger, C., Liu, W., Prior, J.C., Cheung, A.M., Hanley, D.A., Boyd, S.K., Wong, A.K.O., Papaioannou, A., Rahme, E., Goltzman, D., Kreiger, N., Tenenhouse, A., Rahme, E., Richards, J.B., Berger, C., Joyce, C., Kovacs, C.S., Kirkland, S., Kaiser, S.M., Brown, J.P., Bessette, L., Anastassiades, T.P., Towheed, T., Hopman, W.M., Cheung, A.M., Josse, R.G., Wong, A.K.O., Adachi, J.D., Papaioannou, A., Olszynski, W.P., Davison, K.S., Hanley, D.A., Boyd, S.K., Prior, J.C., Kalyan, S., Lentle, B., Patel, M.S., Jackson, S.D., Leslie, W.D.. DOI 10.1007/s11657-020-00822-4

INFECTION IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH GOLIMUMAB Internal Medicine Journal, 2020. Bessette, Louis, Rahman, Proton, Kelsall, John, Purvis, Jane, Rampakakis, Emmanouil, Lehman, Allen J., Rachich, Meagan, Nantel, Francois, Asin-Milan, Odalis.

Ixekizumab for patients with non-radiographic axial spondyloarthritis (COAST-X): a randomised, placebo-controlled trial The Lancet, 2020. Deodhar, A., van der Heijde, D., Gensler, L.S., Kim, T.-H., Maksymowych, W.P., Østergaard, M., Poddubnyy, D., Marzo-Ortega, H., Bessette, L., Tomita, T., Leung, A., Hojnik, M., Gallo, G., Li, X., Adams, D., Carlier, H., Sieper, J., Morin, F., Rahman, P., Ariel, F., Berman, A., Carrio, J., Lucero, E., Cocco, J.M., Hidalgo, R.P., Velasco, J., Viola, D.O., Grisar, J., Resch, H., Scheinecker, C., Melazzi, A.C., Roimicher, L., Scotton, A.S., Rodriguez, A.A.B., Molina, F.F.C., Barragan, S.D., Skinner, C.M., Tena, C.F.P., Remus, C.R.R., Rodriguez, J.C.R., Hong, S.-J., Kang, S.W., Lee, C.K., Lee, E.B., Lee, S.H., Park, M.-C., Lee, S.-H., Dokoupilova, E., Dvorak, Z., Malcova, M., Pvelka, K., Eklund, K.K., Jarvinen, P., Karjalainen, A., Paimela, L., Taniguchi, Y., Tsuda, T., Tada, K., Dobashi, H., Inui, K., Ueki, Y., Matsumoto, Y., Hatta, K., Atsumi, T., Goto, H., Honjo, S., Matsui, K., Takakubo, Y., Neeck, G., Wagner, S., Braun, J., Blicharshi, T., Dudek, A., Hrycai, P., Plebanski, R., Drabiszcak-Piatkowska, J., Brzezicki, J., Krogulec, M., Opris-Belinski, D., Ramazan, A.M., Tronaru, L., van de Sande, M.G., Matsievskaya, G., Schmidt, E., Stanislav, M., Yakushin, S., Ershova, O., Rebroy, A., Churchill, M.A., Flint, K.P., Greenwald, M., Howell, M.P., Kaine, J.L., Kivitz, A., Klein, S.J., Mueller, E.C., Peters, E.A., Querubin, R., Sayers, M.E., Scoville, C.D., Shanahan, J.C., Roseff, R., Hull, J.E., Mallepalli, J.R., Sebai, M.B., Kimmel, S.C., Goddard, D.H., Mease, P.J., Harris, M.D., Mabaquiao, A.R., Diegel, R.J., Thai, C., Rivera, T.L., Perez-De Jesus, A., Soto-Raices, O., Toro-Torres, R., Pantojas, C.. DOI 10.1016/S0140-6736(19)32971-X

Long-term effectiveness and safety of infliximab and golimumab in ankylosing spondylitis patients from a Canadian prospective observational registry BMC Rheumatology, 2020. Rahman, P., Starr, M., Haaland, D., Bessette, L., Teo, M., Rampakakis, E., Lehman, A.J., Nantel, F.. DOI 10.1186/s41927-020-00158-z

MAPPING REAL-WORD RHEUMATOID ARTHRITIS PATIENTS TO CLINICAL TRIAL ELIGIBILITY CRITERIA Internal Medicine Journal, 2020. Keystone, Ed, Olsynski, Wojciech, Bessette, Louis, Rahman, Proton, Rampakakis, Emmanouil, Lehman, Allen J., Asin-Milan, Odalis, Nantel, Francois, Rachich, Meagan.

SAFETY PROFILE OF UPADACITINIB IN RHEUMATOID ARTHRITIS: INTEGRATED ANALYSIS FROM THE SELECT PHASE 3 CLINICAL PROGRAMME Rheumatology, 2020. Cohen, Stanley B., van Vollenhoven, Ronald, Winthrop, Kevin, Zerbini, Cristiano, Tanaka, Yoshiya, Bessette, Louis, Zhang, Ying, Khan, Nasser, Hendrickson, Barbara, Enejosa, Jeffrey V., Burmester, Gerd Rudiger.

A quarter of patients time their early rheumatoid arthritis onset differently than physicians RMD Open, 2019. Ellingwood, L., Kudaeva, F., Schieir, O., Bartlett, S.J., Bessette, L., Boire, G., Hazlewood, G.S., Hitchon, C., Keystone, E., Tin, D., Thorne, C., Bykerk, V.P., Pope, J.. DOI 10.1136/rmdopen-2019-000931

Clinical peripheral enthesitis in the DESIR prospective longitudinal axial spondyloarthritis cohort Clinical and experimental rheumatology, 2019. Nadon, V., Moltó, A., Etcheto, A., Bessette, L., Michou, L., D'Agostino, M.-A., Claudepierre, P., Wendling, D., Haraoui, P., Dougados, M..

Performance of predictive tools to identify individuals at risk of non-traumatic fracture: a systematic review, meta-analysis, and meta-regression Osteoporosis International, 2019. Beaudoin, C., Moore, L., Gagné, M., Bessette, L., Ste-Marie, L.G., Brown, J.P., Jean, S.. DOI 10.1007/s00198-019-04919-6

Tofacitinib in Combination With Methotrexate in Patients With Rheumatoid Arthritis: Clinical Efficacy, Radiographic, and Safety Outcomes From a Twenty-Four–Month, Phase III Study Arthritis and Rheumatology, 2019. van der Heijde, D., Strand, V., Tanaka, Y., Keystone, E., Kremer, J., Zerbini, C.A.F., Cardiel, M.H., Cohen, S., Nash, P., Song, Y.-W., Tegzová, D., Gruben, D., Wallenstein, G., Connell, C.A., Fleischmann, R., Hall, S., Nicholls, D., Rischmueller, M., Baker, M.F., Bessette, L., Cividino, A.A., Haraoui, B., Niall Jones, H., Keystone, E.C., Khraishi, M., Thorne, J., Birbara, C.A., Baraf, H.S.B., Bathon, J.M., Brodsky, A.L., Cush, J.J., Dikranian, A.H., Diri, E., Dura, P.A., Lohr, K.M., Fleischmann, R.M., Griffin, R.M., Halter, D.G., Hargrove, J.K., Bouda, D.W., Reddy Pasya, S.K., Hill, G.L., Jackson, R.E., Kafka, S.P., Kaine, J.L., Katzenstein, P.L., Kempf, K.J., Kolba, K.S., Kremer, J.M., Longley, S., Mathews, S.D., Milton, A.C., Misischia, R.J., Moorman, H.A., Moreland, L.W., Niemer, M.W., Palmer, W.R., Sayers, M.E., Schuette, P.T., Shamim, T., Shergy, W.J., Sikes, D.H., Silverfield, J.C., Siva, C., Taborn, J.D., Walsh, B.T., Wells, A.F., Wolfe, S.M., Adhikari, P., Amano, K., Bae, S.-C., Chandrashekara, S., Chopra, A.K., Hsu, P.-N., Iwahashi, M., Kadel, J.K., Kawabe, Y., Koh, E.-M., Lan, J.-L., Lee, S.-K., Lin, H.-Y., Liou, L.-B., Liu, M.-F., Migita, K., Miyamoto, T., Miyasaka, N., Mori, S., Munakata, Y., Ohta, S., Park, W., Park, S.-H., Rao, U.R., Shim, S.C., Shobha, V., Takasaki, Y., Takeuchi, T., Tanaka, Y., Tohma, S., Tsai, W.-C., Ueki, Y., Veeravalli, S.C.M., Wagh, S., Yamanaka, H., Yoo, B., Batalov, A., Bichoversuska, D., Dvorak, Z., Goranov, I., Hrytsenko, H.M., Kopackova, J., Mosterova, Z., Oparanov, B., Petrov, A., Pokrzywnicka-Gajek, I., Povoroznyuk, V.V., Rosa, J., Ruzga, Z., Settas, L., Stanislavchuk, M.A., Tseluyko, V.I., Vitek, P., de Freitas Zerbini, C.A., Brenol, J.C.T., Cardiel-Rios, M.H., Escalante, W.J.O., Maldonado-Lopez, M.C., Jaller Raad, J.J., Hernandez, J.D.M., Jauregui, E.A., Keiserman, M.W., Melazzi, A.C.C., Pascual-Ramos, V., Pinto, L.T., Radominski, S.C., Ximenes, A.C., de Morales, S.V.. DOI 10.1002/art.40803

Upadacitinib Versus Placebo or Adalimumab in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate: Results of a Phase III, Double-Blind, Randomized Controlled Trial Arthritis and Rheumatology, 2019. Fleischmann, R., Pangan, A.L., Song, I.-H., Mysler, E., Bessette, L., Peterfy, C., Durez, P., Ostor, A.J., Li, Y., Zhou, Y., Othman, A.A., Genovese, M.C.. DOI 10.1002/art.41032

Use of disease-modifying anti-rheumatic or anti-tumour necrosis factor drugs and risk of hospitalized infection in ankylosing spondylitis Scandinavian Journal of Rheumatology, 2019. Moura, C.S., Rahme, E., Maksymowych, W.P., Abrahamowicz, M., Bessette, L., Bernatsky, S.. DOI 10.1080/03009742.2018.1470253

Effectiveness and safety of certolizumab pegol in rheumatoid arthritis patients in Canadian practice: 2-year results from the observational FαsT-CAN study Therapeutic Advances in Musculoskeletal Disease, 2019/01. Louis Bessette, Boulos Haraoui, Andrew Chow, Isabelle Fortin, Sanjay Dixit, Majed Khraishi, Derek Haaland, Sami Elmoufti, Fabienne Staelens, Irina Bogatyreva, Jerry Syrotuik, Saeed Shaikh. DOI 10.1177/1759720X19831151

ACHIEVING A LOW DISEASE STATE WITHIN FIRST 3 MONTHS IN EARLY RHEUMATOID ARTHRITIS RESULTS IN LOWER FATIGUE OVER 5 YEARS Annals of the Rheumatic Diseases, 2019. Holdren, Melissa, Schieir, Orit, Bartlett, Susan J., Bessette, Louis, Boire, Gilles, Hazlewood, Glen, Hitchon, Carol, Keystone, Edward, Tin, Diane, Thorne, Carter, Bykerk, Vivian, Pope, Janet. DOI 10.1136/ANNRHEUMDIS-2019-EULAR.4414

Persistence rates of abatacept and TNF inhibitors used as first or second biologic DMARDs in the treatment of rheumatoid arthritis: 9 years of experience from the Rhumadata® clinical database and registry Arthritis Research and Therapy, 2019. Choquette, D., Bessette, L., Alemao, E., Haraoui, B., Postema, R., Raynauld, J.-P., Coupal, L.. DOI 10.1186/s13075-019-1917-8

Safety and effectiveness of upadacitinib or adalimumab plus methotrexate in patients with rheumatoid arthritis over 48 weeks with switch to alternate therapy in patients with insufficient response Annals of the Rheumatic Diseases, 2019. Fleischmann, R.M., Genovese, M.C., Enejosa, J.V., Mysler, E., Bessette, L., Peterfy, C., Durez, P., Ostor, A., Li, Y., Song, I.-H.. DOI 10.1136/annrheumdis-2019-215764

Stressful life events are common in the year prior to RA onset and are associated with worse symptoms and QOL Quality of Life Research, 2019. Andersen, Nicole, Schieir, Orit, Valois, Marie-France, Boire, Gilles, Bessette, Louis, Thorne, Carter, Pope, Janet, Hitchon, Carol, Hazlewood, Glen, Tin, Diane, Keystone, Ed, Bykerk, Vivian, Bartlett, Susan.

High Adherence to System-Level Performance Measures for Rheumatoid Arthritis in a National Early Arthritis Cohort Over Eight Years Arthritis Care and Research, 2018. Barber, C.E.H., Schieir, O., Lacaille, D., Marshall, D.A., Barnabe, C., Hazlewood, G., Thorne, J.C., Ahluwalia, V., Bartlett, S.J., Boire, G., Haraoui, B., Hitchon, C., Keystone, E., Tin, D., Pope, J.E., Denning, L., Bykerk, V.P., Morin, F., Villeneuve, É., Baron, M., Colmegna, I., Fallavollita, S., Haaland, D., Zummer, M., Bessette, L., Akhavan, P., Rubin, L., Nair, B., Penney, C., Jamal, S., Joshi, R.. DOI 10.1002/acr.23439

Impact of the Adalimumab Patient Support Program on Clinical Outcomes in Ankylosing Spondylitis: Results from the COMPANION Study Rheumatology and Therapy, 2018. Bessette, L., Lebovic, G., Millson, B., Charland, K., Donepudi, K., Gaetano, T., Remple, V., Latour, M.G., Gazel, S., Laliberté, M.-C., Thorne, C.. DOI 10.1007/s40744-018-0109-3

Canada's Study of Adherence Outcomes in Patients Receiving Adalimumab: 3-year Results From the COMPANION Study Clinical Therapeutics, 2018. Marshall, J.K., Bessette, L., Shear, N.H., Lebovic, G., Glass, J., Millson, B., Gaetano, T., Gazel, S., Latour, M.G., Laliberté, M.-C., Thorne, J.C.. DOI 10.1016/j.clinthera.2018.04.017

Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial The Lancet, 2018. van der Heijde, D., Cheng-Chung Wei, J., Dougados, M., Mease, P., Deodhar, A., Maksymowych, W.P., Van den Bosch, F., Sieper, J., Tomita, T., Landewé, R., Zhao, F., Krishnan, E., Adams, D.H., Pangallo, B., Carlier, H., Churchill, M., Flint, K., Gladstein, G., Greenwald, M., Howell, M., Ince, A., Kaine, J., Mehta, D., Peters, E., Querubin, R., Reveille, J., Roseff, R., Diegel, R., Thai, C., Bessette, L., Morin, F., Rahman, P., Barrera Rodriguez, A.A., Cons-Molina, F., Duran Barragan, S., Skinner, C., Pacheco Tena, C., Ramos Remus, C., Rizo Rodriguez, J.C., Hong, S.-J., Lee, Y.-A., Ju, J.H., Kang, S.W., Kim, T.-H., Lee, C.K., Lee, E.B., Lee, S.H., Park, M.-C., Shin, K., Lee, S.-H., Chen, H.-A., Chen, Y.-C., Hsieh, S.-C., Lan, J.-L., Dvorak, Z., Moravcova, R., Malcova, M., Taniguchi, Y., Kishimoto, M., Tada, K., Dobashi, H., Inui, K., Ueki, Y., Matsumoto, Y., Koyama, Y., Hatta, K., Atsumi, T., Goto, H., Matsui, K., Takakubo, Y., Neeck, G., Poddubnyy, D., Rubbert-Roth, A., Szymanska, M., Blicharski, T., Dudek, A., Racewicz, A., Wojciechowski, R., van de Sande, M., Griep, E., Nurmohamed, M., Matsievskaya, G., Shmidt, E., Stanislav, M., Yakushin, S., Ershova, O., Rebrov, A., Balazs, T., Cseuz, R., Drescher, E., Poor, G.. DOI 10.1016/S0140-6736(18)31946-9

Overweight, Obesity, and the Likelihood of Achieving Sustained Remission in Early Rheumatoid Arthritis: Results From a Multicenter Prospective Cohort Study Arthritis Care and Research, 2018. Schulman, E., Bartlett, S.J., Schieir, O., Andersen, K.M., Boire, G., Pope, J.E., Hitchon, C., Jamal, S., Thorne, J.C., Tin, D., Keystone, E.C., Haraoui, B., Goodman, S.M., Bykerk, V.P., Ahluwalia, V., Akhavan, P., Barra, L., Barber, C., Barnabe, C., Baron, M., Bessette, L., Bykerk, V., Colmegna, I., Fallavollita, S., Haaland, D., Hazlewood, G., Joshi, R., Kuriya, B., Larche, M., Lyddell, C., Nair, B., Penney, C., Rubin, L., Tremblay, J.L., Villeneuve, E., Zummer, M.. DOI 10.1002/acr.23457

Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial The Lancet, 2018. Burmester, G.R., Kremer, J.M., Van den Bosch, F., Kivitz, A., Bessette, L., Li, Y., Zhou, Y., Othman, A.A., Pangan, A.L., Camp, H.S.. DOI 10.1016/S0140-6736(18)31115-2

Sharing ongoing care with primary care physicians opens up opportunity for timelier and earlier care by rheumatologists for patients with new inflammatory polyarthritis Journal of Rheumatology, 2018. Nguyen, P., Julien, A.-S., Bessette, L., Fortin, P.R., Michou, L.. DOI 10.3899/jrheum.170494

Impact of the Adalimumab Patient Support Program's Care Coach Calls on Persistence and Adherence in Canada: An Observational Retrospective Cohort Study Clinical Therapeutics, 2018. Marshall, J.K., Bessette, L., Thorne, C., Shear, N.H., Lebovic, G., Gerega, S.K., Millson, B., Oraichi, D., Gaetano, T., Gazel, S., Latour, M.G., Laliberté, M.-C.. DOI 10.1016/j.clinthera.2018.02.001

Number, Location, and Time Since Prior Fracture as Predictors of Future Fracture in the Elderly From the General Population Journal of Bone and Mineral Research, 2018. Beaudoin, C., Jean, S., Moore, L., Gamache, P., Bessette, L., Ste-Marie, L.-G., Brown, J.P.. DOI 10.1002/jbmr.3526

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