Répertoire du corps professoral
Marie-Claude Vohl
Professeure titulaire
Marie-Claude.Vohl@fsaa.ulaval.ca
Investigating diet-rosuvastain interactions: a controlled-feeding
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2026
au 30 septembre 2031
Découverte et caractérisation d'effets de nouveaux -biotiques sur la santé cardiométabolique et neurognitive au cours du vieillissement
Organisme(s) subventionnaire(s): Lallemand Inc.
Type de financement: Contrat
Établissement tête: Université Laval
Du 17 mars 2026
au 17 mars 2029
Impact de la susceptibilité génétique à l’obésité sur le contrôle de l’appétit et du poids corporel en réponse à une intervention nutritionnelle
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2025
au 31 mars 2027
Institut sur la nutrition et les aliments fonctionnels
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): TransBIOTech, Université Concordia, Institut national de recherche scientifique (INRS), Université du Québec à Rimouski, Fonds de recherche du Québec - Nature et technologies, Université McGill, Université Laval - Fonds internes, Merinov - Centre d'innovation de l'aquaculture et des pêches du Québec
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024
au 31 mars 2030
Dairy product consumption and risk of type 2 diabetes: a large, prospective, multi-omics investigation among Canadian adults and an assessment of the quality of evidence.
Programme: Dairy Research Cluster 4 - Human Nutrition and Health
Organisme(s) subventionnaire(s): Les producteurs laitiers du Canada, Danish Dairy Research, National Dairy Council
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024
au 31 décembre 2028
Pôle de recherche et d'innovation pour accélérer la transition vers des systèmes alimentaires durables et résilients
Programme: APPEL à Pôle de recherche et d’innovation du FRQNT – Secteur Bioalimentaire
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Nature et technologies
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2022
au 31 mars 2027
Identifying nutrition and lifestyle mediators of genetic susceptibility to obesity: towards a precision lifestyle medicine approach to obesity prevention
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2021
au 31 mars 2027
Financements des 2 dernières années
Définir l'impact épigénétique du complexe KAP1-ZNF707 afin de mieux comprendre son rôle dans le métabolisme hépatique
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2025
au 31 mars 2026
Cardiometabolic Week 2025 - Joint meeting of the Research Network on Cardiometabolic Health, Diabetes and Obesity, the Quebec Society of Lipidology, Nutrition and Metabolism and MyRoad Health Research Training Platform
Programme: Subventions de planification et dissémination – Programme d’appui communautaire des instituts
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 novembre 2024
au 31 octobre 2025
Les voies métaboliques : une chaîne YouTube et une balado pour démocratiser la santé cardiométabolique
Programme: Subventions de planification et dissémination – Programme d’appui communautaire des instituts
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 novembre 2024
au 31 mars 2025
Predicting weight loss and metabolic improvements after bariatric surgery through a novel genetic and epigenetic score
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2020
au 31 mars 2026
Identifying the biological basis of GWAS hits for plasma triglyceride response to an omega-3 fatty acid supplementation
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2020
au 31 mars 2026
3alpha-hydroxysteroid dehydrogenase type 3 as a modulator of human adipose tissue function and distribution
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2020
au 31 mars 2026
Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3
Programme: Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 novembre 2019
au 31 octobre 2024
Dissecting host-microbiome modifiers of type 2 diabetes risk
Programme: Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 novembre 2019
au 31 octobre 2024
Encadrements terminés dans les 5 dernières années
Publications des 5 dernières années
Eating Behaviors, Dietary Intakes, and Other Lifestyle Behaviors as Mediators of Genetic Susceptibility to Obesity: A Systematic Review Obesity Reviews, 2026/10/15. Benoît Boulanger, Laurence Pelletier, Angelo Tremblay, Marie‐Claude Vohl, Vicky Drapeau, Louis Pérusse. DOI 10.1111/obr.70239
Knowledge and Interest in Nutritional Genomics Among Clinical Dietitians in Kuwait: A Cross-Sectional Study Lifestyle Genomics, 2026/09/24. Mohammad M H Abdullah, Fatemah Osama Al-muaili, Esra Shishtar, Peter Eck, Marie-Claude Vohl, Ahmad Alsaber. DOI 10.1159/lfg/adlag003
Genome-wide association meta-analysis of eating behavior traits revealed one susceptibility locus for emotional eating Molecular Psychiatry, 2026/09/14. Manon Muntaner, Katrin Horn, Blandine de Lauzon-Guillain, Muriel Tafflet, Teemu Palviainen, Kirsi H. Pietiläinen, Guiomar Masip, Braxton D. Mitchell, Christian Couture, Marie-Claude Vohl, Janne Pott, Philippe Amouyel, Monique Romon, Louis Perusse, Nanette Steinle, Jaakko Kaprio, Barbara Heude, Anke Tönjes, Peter Kovacs, Markus Scholz, Aline Meirhaeghe. DOI 10.1038/s41380-026-03889-6
An integrated proteogenomic investigation of the human liver uncovers molecular drivers of steatotic liver disease 2026/06/06. Émilie Gobeil, Jérôme Bourgault, Malie Enault, Valérie Côté, Patricia L. Mitchell, Louis-Jacques Ruel, Arnaud S. Girard, Marie-Claude Vohl, Benoit J. Arsenault. DOI 10.64898/2026.06.04.26354903
Agnostic polygenic prediction of weight loss after bariatric surgery JCI Insight, 2026/05/08. Bastien Vallée Marcotte, Juan de Toro-Martín, André Tchernof, Louis Pérusse, Simon Marceau, Marie-Claude Vohl. DOI 10.1172/jci.insight.198133
Study protocol and pilot study results for a clinical intervention trial of PKU carriers and non-carriers: the Phe for Me trial ORPHANET JOURNAL OF RARE DISEASES, 2026. DOI 10.1186/S13023-025-04131-2
PKU carriers exhibit altered mood and cognition in response to Lphenylalanine compared to non-carriers: The Phe for Me trial MOLECULAR GENETICS AND METABOLISM, 2026. DOI 10.1016/J.YMGME.2026.109787
Integrative genetic and liver transcriptomic analyses identify TRIB1AL as a target for steatotic liver disease JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2026. DOI 10.1210/CLINEM/DGAG043
Impact of <i>AKR1C2</i> and <i>AKR1C3</i> single-nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2026. DOI 10.1152/AJPENDO.00512.2024
Functional gut microbiome signatures underlying interindividual variability in metabolic responses to red raspberry consumption SCIENTIFIC REPORTS, 2026. DOI 10.1038/S41598-026-45955-7
Exploring mental health outcomes among genetic carriers and non-carriers of phenylketonuria (PKU) MOLECULAR GENETICS AND METABOLISM, 2026. DOI 10.1016/J.YMGME.2026.109784
RNA interference versus antibody-based PCSK9 inhibition for the prevention of cardiovascular disease: a drug-target Mendelian randomization study CARDIOVASCULAR RESEARCH, 2025. DOI 10.1093/CVR/CVAF078
Polygenic prediction of body mass index and obesity through the life course and across ancestries NATURE MEDICINE, 2025. DOI 10.1038/S41591-025-03827-Z
Pharmaco-nutraceutical improvement of the response to obeticholic acid with omega-3 polyunsaturated fatty acids BIOCHEMICAL JOURNAL, 2025. DOI 10.1042/BCJ20253113
Machine learning-driven discovery of bioactive peptides from duckweed (Lemnaceae) protein hydrolysates: Identification and experimental validation of 20 novel antihypertensive, antidiabetic, and/or antioxidant peptides FOOD CHEMISTRY, 2025. DOI 10.1016/J.FOODCHEM.2025.144029
Impact of AKR1C2 and AKR1C3 single nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity medRxiv, 2025. DOI 10.1101/2025.10.10.25337731
Exploring novel antifungal peptides from peptic hydrolysis of chicken cruor protein via regression-based machine learning approach FOOD CHEMISTRY, 2025. DOI 10.1016/J.FOODCHEM.2024.142606
Fecal deoxycholic acid associates with diet, intestinal microbes, and total bilirubin in primary sclerosing cholangitis JHEP Reports, 2024/12. Connie Chan, Mateus Lemos, Peter Finnegan, William Gagnon, Richard Dean, Maryam Yazdanafar, Joseph Zepeda, Marie-Claude Vohl, Michael Trauner, Joshua R. Korzenik, Olivier Barbier, Maria L. Marco, Christopher L. Bowlus. DOI 10.1016/j.jhepr.2024.101188
Upcycling calf cruor slaughterhouse by-product by peptic hydrolysis and identification of three novel antifungal peptides following a regression based-machine learning approach FOOD RESEARCH INTERNATIONAL, 2024. DOI 10.1016/J.FOODRES.2024.115045
Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients-it takes a village APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2024. DOI 10.1139/APNM-2024-0111
TOTUM-63 (T63), a Novel Plant-Based Polyphenol-Rich Substance, Improves Glucose Homeostasis and Modulates Gut Microbiota Diversity among Adults at Increased Cardiometabolic Risk DIABETES, 2024. DOI 10.2337/DB24-725-P
Substituting Refined fi ned Sugars With Maple Syrup Decreases Key Cardiometabolic Risk Factors in Individuals With Mild Metabolic Alterations: A Randomized, Double-Blind, Controlled Crossover Trial JOURNAL OF NUTRITION, 2024. DOI 10.1016/J.TJNUT.2024.08.014
Revisiting multi-omics-based predictors of the plasma triglyceride response to an omega-3 fatty acid supplementation(vol 11 , 1327863 , 2024) FRONTIERS IN NUTRITION, 2024. DOI 10.3389/FNUT.2024.1388485
Revisiting multi-omics-based predictors of the plasma triglyceride response to an omega-3 fatty acid supplementation FRONTIERS IN NUTRITION, 2024. DOI 10.3389/FNUT.2024.1327863
RNA interference versus antibody-based PCSK9 inhibition for the prevention of cardiovascular disease: A drug-target Mendelian randomization study CIRCULATION, 2024. DOI 10.1161/CIRC.150.SUPPL_1.4141244
Metabolic-associated fatty liver disease is characterized by a post-oral glucose load hyperinsulinemia in individuals with mild metabolic alterations AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2024. DOI 10.1152/AJPENDO.00294.2023
Informing Evidence-based Practice in Nutritional Genomics: An Educational Needs Assessment of Nutrition Care Providers in Canada CANADIAN JOURNAL OF DIETETIC PRACTICE AND RESEARCH, 2024. DOI 10.3148/CJDPR-2024-010
Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk EUROPEAN HEART JOURNAL, 2024. DOI 10.1093/EURHEARTJ/EHAD845
Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets EUROPEAN HEART JOURNAL OPEN, 2024. DOI 10.1093/EHJOPEN/OEAE043
Camu-camu decreases hepatic steatosis and liver injury markers in overweight, hypertriglyceridemic individuals: A randomized crossover trial CELL REPORTS MEDICINE, 2024. DOI 10.1016/J.XCRM.2024.101682
Update of a Genetic Risk Score Predictive of the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation in the FAS Study NUTRIENTS, 2023. DOI 10.3390/NU15051156
Precision Nutrition for Cardiovascular Diseases Prevention LIFESTYLE GENOMICS, 2023. DOI 10.1159/000529054
Post-Oral Glucose Load Hyperinsulinemia in Individuals with Metabolic Syndrome and Metabolic-Associated Fatty Liver Disease-First Steps toward the Development of Type 2 Diabetes? DIABETES, 2023. DOI 10.2337/DB23-1590-P
Post-OGTT Low Blood Glucose in Individuals with Metabolic Syndrome, Metabolic Phenotypes, and Metabolic-Associated Fatty Liver Disease DIABETES, 2023. DOI 10.2337/DB23-1586-P
Impact of maternal cardiometabolic status after bariatric surgery on the association between telomere length and adiposity in offspring SCIENTIFIC REPORTS, 2023. DOI 10.1038/S41598-023-47813-2
Heuristic approach uncovering biological significance of gene-lifestyle interactions in cardiometabolic traits. LIFESTYLE GENOMICS, 2023. DOI 10.1159/000531181
Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets medRxiv, 2023. DOI 10.1101/2023.12.05.23299567
Associations of fecal bile acids, diet, and intestinal microbes with markers of disease progression in primary sclerosing cholangitis disease JOURNAL OF HEPATOLOGY, 2023.
A discriminant analysis of plasma metabolomics for the assessment of metabolic responsiveness to red raspberry consumption FRONTIERS IN NUTRITION, 2023. DOI 10.3389/FNUT.2023.1104685
Impact of Blueberry Consumption on the Human Fecal Bileacidome: A Pilot Study of Bile Acid Modulation by Freeze-Dried Blueberry Nutrients, 2022/09/17. William Gagnon, Véronique Garneau, Jocelyn Trottier, Mélanie Verreault, Charles Couillard, Denis Roy, André Marette, Jean-Philippe Drouin-Chartier, Marie-Claude Vohl, Olivier Barbier. DOI 10.3390/nu14183857
Understanding Gene-Lifestyle Interaction in Obesity: The Role of Mediation versus Moderation LIFESTYLE GENOMICS, 2022. DOI 10.1159/000523813
Towards a Standardized Definition of Medical Nutrition Therapy and Regulatory Reform in Canada CANADIAN JOURNAL OF DIETETIC PRACTICE AND RESEARCH, 2022. DOI 10.3148/CJDPR-2021-033
Super-enhancer signature reveals key mechanisms associated with resistance to non-alcoholicsteatohepatitis in humans with obesity bioRxiv, 2022. DOI 10.1101/2021.08.20.457162
Raspberry consumption: identification of distinct immune-metabolic response profiles by whole blood transcriptome profiling (vol 101C, 108946, 2022) JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2022. DOI 10.1016/J.JNUTBIO.2022.109035
Raspberry consumption: identification of distinct immune-metabolic response profiles by whole blood transcriptome profiling JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2022. DOI 10.1016/J.JNUTBIO.2022.108946
Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review BMJ OPEN, 2022. DOI 10.1136/BMJOPEN-2021-054417
Molecular remodeling of adipose tissue is associated with metabolic recovery after weight loss surgery JOURNAL OF TRANSLATIONAL MEDICINE, 2022. DOI 10.1186/S12967-022-03485-6
Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases COMMUNICATIONS MEDICINE, 2022. DOI 10.1038/S43856-022-00196-3
Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease METABOLITES, 2022. DOI 10.3390/METABO12050440
Impact of Blueberry Consumption on the Human Fecal Bileacidome: A Pilot Study Preprints, 2022. DOI 10.20944/PREPRINTS202208.0202.V1
Gut Microbial Signatures of Distinct Trimethylamine N-Oxide Response to Raspberry Consumption NUTRIENTS, 2022. DOI 10.3390/NU14081656
Guiding Global Best Practice in Personalized Nutrition Based on Genetics: The Development of a Nutrigenomics Care Map JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS, 2022. DOI 10.1016/J.JAND.2021.02.008
Gene expression signatures and cardiometabolic outcomes following 8-week mango consumption in individuals with overweight/obesity FRONTIERS IN NUTRITION, 2022. DOI 10.3389/FNUT.2022.918844
Eco-Evolutionary Dynamics of the Human-Gut Microbiota Symbiosis in a Changing Nutritional Environment EVOLUTIONARY BIOLOGY, 2022. DOI 10.1007/S11692-022-09569-X
Clinical Practice Guidelines Using GRADE and AGREE II for the Impact of Genetic Variants on Plasma Lipid/Lipoprotein/Apolipoprotein Responsiveness to Omega-3 Fatty Acids FRONTIERS IN NUTRITION, 2022. DOI 10.3389/FNUT.2021.768474
Changes in systolic blood pressure, postprandial glucose, and gut microbial composition following mango consumption in individuals with overweight and obesity APPLIED PHYSIOLOGY NUTRITION AND METABOLISM, 2022. DOI 10.1139/APNM-2021-0637
Are Machine Learning Algorithms More Accurate in Predicting Vegetable and Fruit Consumption Than Traditional Statistical Models? An Exploratory Analysis FRONTIERS IN NUTRITION, 2022. DOI 10.3389/FNUT.2022.740898
Appraisal of Gene-Environment Interactions in GWAS for Evidence-Based Precision Nutrition Implementation CURRENT NUTRITION REPORTS, 2022. DOI 10.1007/S13668-022-00430-3
Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity JCI INSIGHT, 2022. DOI 10.1172/JCI.INSIGHT.159204
Altered branched-chain α-keto acid metabolism is a feature of NAFLD in individuals with severe obesity medRxiv, 2022. DOI 10.1101/2022.02.07.22270618
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers GENOME MEDICINE, 2022. DOI 10.1186/S13073-022-01077-Z
Salmon peptides limit obesity-associated metabolic disorders by modulating a gut-liver axis in vitamin D-deficient mice OBESITY, 2021. DOI 10.1002/OBY.23244
Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid NUTRIENTS, 2021. DOI 10.3390/NU13082617
OMEGA-3 POLYUNSATURATED FATTY ACIDS IMPROVE THE RESPONSE TO OBETICHOLIC ACID IN VITRO: A PHARMACO-NUTRACEUTICAL STUDY HEPATOLOGY, 2021.
Mendelian randomization analysis identifies blood tyrosine levels as a biomarker of non-alcoholic fatty liver disease medRxiv, 2021. DOI 10.1101/2021.11.26.21266879
Liking for foods high in salt and fat is associated with a lower diet quality but liking for foods high in sugar is not - Results from the PREDISE study FOOD QUALITY AND PREFERENCE, 2021. DOI 10.1016/J.FOODQUAL.2020.104073
Individuals with self-determined motivation for eating have better overall diet quality: Results from the PREDISE study APPETITE, 2021. DOI 10.1016/J.APPET.2021.105426
Identification of Phenotypic Lipidomic Signatures in Response to Long Chain n-3 Polyunsaturated Fatty Acid Supplementation in Humans JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2021. DOI 10.1161/JAHA.120.018126
Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease CELL REPORTS MEDICINE, 2021. DOI 10.1016/J.XCRM.2021.100437
Comment on "Guiding Global Best Practice in Personalized Nutrition Based on Genetics: The Development of a Nutrigenomics Care Map" Response JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS, 2021. DOI 10.1016/J.JAND.2021.04.017
Cholecalciferol Supplementation Does Not Prevent the Development of Metabolic Syndrome or Enhance the Beneficial Effects of Omega-3 Fatty Acids in Obese Mice JOURNAL OF NUTRITION, 2021. DOI 10.1093/JN/NXAB002
Associations of Intake of Free and Naturally Occurring Sugars from Solid Foods and Drinks with Cardiometabolic Risk Factors in a Quebec Adult Population: The PREDISE (PREDicteurs Individuels, Sociaux et Environnementaux) Study JOURNAL OF NUTRITION, 2021. DOI 10.1093/JN/NXAB042
Associations Between Nutrition Knowledge and Overall Diet Quality: The Moderating Role of Sociodemographic Characteristics-Results From the PREDISE Study AMERICAN JOURNAL OF HEALTH PROMOTION, 2021. DOI 10.1177/0890117120928877JOURNALS.SAGEPUB.COM/HOME/AHP
An 8-week freeze-dried blueberry supplement impacts immune-related pathways: a randomized, double-blind placebo-controlled trial GENES AND NUTRITION, 2021. DOI 10.1186/S12263-021-00688-2
A multivariable Mendelian randomization analysis disentangling the causal relations between abdominal obesity, non-alcoholic fatty liver disease and cardiometabolic diseases medRxiv, 2021. DOI 10.1101/2021.09.28.21264201
A Systematic Review and Recommendations Around Frameworks for Evaluating Scientific Validity in Nutritional Genomics FRONTIERS IN NUTRITION, 2021. DOI 10.3389/FNUT.2021.789215
<i>AKR1C2</i> and <i>AKR1C3</i> expression in adipose tissue: Association with body fat distribution and regulatory variants MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2021. DOI 10.1016/J.MCE.2021.111220
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