Répertoire du corps professoral

Développement d’une thérapie d’atténuation basée sur un monosaccharide pour les dystrophies musculaires, avec un accent sur la dystrophie musculaire de Duchenne
Programme: Excellence en recherche - Projets d'envergure
Organisme(s) subventionnaire(s): Fondation du CHU de Québec
Type de financement: Subvention
Établissement tête: Université Laval
Du 28 mars 2025 au 31 mars 2027

Financements des 2 dernières années

Manufacturing of antigens and adjuvants for development of vaccines (MAAV)
Programme: Fonds d'innovation (FI)
Organisme(s) subventionnaire(s): Fondation Canadienne pour l'innovation (La), Ministère de la Santé et des Services sociaux, Fondation du CHU de Québec
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2021 au 31 mars 2024

Development of a monosaccharide therapy using N-acetylglucosamine to mitigate Duchenne muscular dystrophy
Organisme(s) subventionnaire(s): The Foundation for gene and cell therapy Jesse's Journey
Type de financement: Subvention
Établissement tête: Université Laval
Du 31 mai 2021 au 30 mai 2024

Encadrements terminés dans les 5 dernières années

Christina Frederick, Maîtrise en microbiologie - avec mémoire

Jose Arquimides Echanove Juan, Doctorat en microbiologie-immunologie

Publications des 5 dernières années

N-Acetylglucosamine Facilitates Coordinated Myoblast Flow, Forming the Foundation for Efficient Myogenesis Skeletal Muscle, 2025/10/30. Masahiko S. Satoh, Ann Rancourt, Guillaume St-Pierre, Elizabeth Bouchard, Maude Fillion, Kana Hagiwara, Kazuki Nakajima, Sachiko Sato. DOI 10.1101/2024.08.25.609576

Improvement of Spontaneous Locomotor Activity in a Murine Model of Duchenne Muscular Dystrophy by N‐Acetylglucosamine Alone and in Combination With Prednisolone The FASEB Journal, 2025/09/30. Masahiko. S. Satoh, Guillaume St‐Pierre, Ann Rancourt, Maude Fillion, Sachiko Sato. DOI 10.1096/fj.202500196R

Decoding the multifaceted roles of galectins in self-defense Seminars in Immunology, 2025/03. Sachiko Sato, Jun Iwaki, Jun Hirabayashi. DOI 10.1016/j.smim.2024.101926

Improvement of Spontaneous Locomotor Activity in a Murine Model of Duchenne Muscular Dystrophy by N-Acetylglucosamine Alone and in Combination with Prednisolone 2024/08/26. Masahiko. S. Satoh, Guillaume St-Pierre, Ann Rancourt, Maude Fillion, Sachiko Sato. DOI 10.1101/2024.08.25.609562

Why does galectin-3 have a unique intrinsically disordered region? “Raison d’être” for the disordered structure and liquid–liquid phase separation –Part 2– Glycoforum, 2023/06/01. Sachiko Sato. DOI 10.32285/glycoforum.26A8

Why does galectin-3 have a unique intrinsically disordered region? Glycoforum, 2023/02/01. Sachiko Sato. DOI 10.32285/glycoforum.26A1

Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppression. eLife, 2022/09/20. Rancourt A, Sato S, Satoh MS. DOI 10.7554/elife.72498

Milk oligosaccharides and galectins: Spin-off version - from a glycoscience point of view Glycoforum, 2021/10/01. Junko Nio-Kobayashi, Tadasu Urashima, Jun Hirabayashi, Sachiko Sato. DOI 10.32285/glycoforum.24A13

Milk oligosaccharides and galectins: Spin-off version - from a glycoscience point of viewDo milk oligosaccharides get altered under breeding conditions? An underlying mechanism for structural conversion and diversification Glycoforum, 2021/08/02. Tadasu Urashima, Sachiko Sato, Junko Nio-Kobayashi, Jun Hirabayashi. DOI 10.32285/glycoforum.24A11

Microglia-derived galectin-3 in neuroinflammation; a bittersweet ligand? Medicinal research reviews, 2021/03/18. Rahimian R, Béland LC, Sato S, Kriz J. DOI 10.1002/med.21784

Mammalian Cytosolic Galectins Act as Damage-Associated Molecular Patterns, Resolution-Associated Molecular Patterns, and Pattern-Recognition Receptors in Innate Immunity Comprehensive Glycoscience 2nd edition, 2021. Sachiko Sato.

Introduction to GalectinsExperimental Protocols and Unsolved Questions (Narratives) Glycoforum, 2020/10/01. Jun Hirabayashi, Sachiko Sato. DOI 10.32285/glycoforum.23A14

Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection. PLoS pathogens, 2020/08/04. Snarr BD, St-Pierre G, Ralph B, Lehoux M, Sato Y, Rancourt A, Takazono T, Baistrocchi SR, Corsini R, Cheng MP, Sugrue M, Baden LR, Izumikawa K, Mukae H, Wingard JR, King IL, Divangahi M, Satoh MS, Yipp BG, Sato S, Sheppard DC. DOI 10.1371/journal.ppat.1008741

Glucosamine-mediated immunomodulation after stroke is sexually dimorphic. Brain, behavior, & immunity - health, 2020/02/05. Rahimian R, Lalancette-Hébert M, Weng YC, Sato S, Kriz J. DOI 10.1016/j.bbih.2020.100041

Metazoan Soluble β-Galactoside-Binding Lectins, Galectins: Methods for Purification, Characterization of Their Carbohydrate-Binding Specificity, and Probing Their Ligands. Methods in molecular biology (Clifton, N.J.), 2020/01/01. St-Pierre G, Rancourt A, Sato S. DOI 10.1007/978-1-0716-0430-4_5