Répertoire du corps professoral

Variole simienne, immunité humorale et cellulaire post vaccination. Développement des techniques.
Programme: Développement de la recherche (FC)
Organisme(s) subventionnaire(s): CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 31 mars 2023 au31 mars 2025

Évaluation in vitro et ex vivo de nouveaux antiviraux contre les virus respiratoires
Programme: Développement de la recherche (FC)
Organisme(s) subventionnaire(s): CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 15 février 2023 au31 mars 2026

Émergence des virus respiratoires post pandémie
Programme: Développement de la recherche (FC)
Organisme(s) subventionnaire(s): CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2022 au31 mars 2025

Financements des 2 dernières années

SO06 QC07 Sentinel Surveillance for Severe Outcomes of Laboratory-Confirmed Influenza in Adults for the Annual Influenza Season and for Confirmed and Suspected Cases Of Covid-19/Sars-Cov-2 Acute Respiratory Disease, Covid-19[...]
Programme: Réseau canadien de recherche sur l’immunisation
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Dalhousie University
Du 1 avril 2022 au31 mars 2023

Immunité cellulaire et séroprévalence des anticorps contre SARS-CoV-2 : caractérisation de trois populations de travailleurs de l'alimentation- Amendement
Programme: Développement de la recherche (FC)
Organisme(s) subventionnaire(s): CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2022 au31 mars 2024

SO05 QC07, Sentinel surveillance for confirmed and suspected cases of covid-19/covsars-2 acute respiratory disease, covid-19 vaccine effectiveness and adverse events following sars-cv-2 vaccines: A study of the Serious Outcomes Surveillance
Programme: Réseau canadien de recherche sur l’immunisation
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2021 au30 septembre 2023

Immunité cellulaire et séroprévalence des anticorps contre SARS-COV-2: Caractérisation de trois populations de travailleurs de l'alimentation
Programme: Groupe de travail sur l'immunité face à la COVID 19
Organisme(s) subventionnaire(s): Agence de la santé publique du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 novembre 2020 au30 septembre 2023

Hospital-based surveillance of influenza and routine monitoring of seasonal influenza vaccine effectiveness (VE)
Organisme(s) subventionnaire(s): Agence de la santé publique du Canada
Type de financement: Subvention
Établissement tête: Dalhousie University
Du 1 novembre 2020 au30 septembre 2022

Development of a portable point-of-care device for rapid testing of SARS-CoV-2
Programme: Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19)
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 17 mars 2020 au31 mars 2023

How to better manage infectious diseases in ER by triage with molecular mini-panels for the rapid detection of highly transmissible pathogens
Organisme(s) subventionnaire(s): Ministère de l'Économie, de la Science et de l'Innovation, GenePOC inc., CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2018 au30 septembre 2022

Discovering pathways to successful aging in HIV infection
Programme: Programme de subvention d'équipe
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université de Montréal
Du 1 avril 2018 au31 mars 2023

Randomized Trial to Prevent Vascular Events in HIV-REPRIEVE (A5332)
Programme: Subvention de recherche
Organisme(s) subventionnaire(s): National Institute of Health (USA)
Type de financement: Subvention
Établissement tête: Harvard University
Du 1 mai 2015 au30 avril 2024

Publications des 5 dernières années

Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy–Treated Individuals With Undetectable Viremia The Journal of Infectious Diseases, 2024/03/14. Mehdi Benlarbi, Jonathan Richard, Catherine Bourassa, William D Tolbert, Carl Chartrand-Lefebvre, Gabrielle Gendron-Lepage, Mohamed Sylla, Mohamed El-Far, Marc Messier-Peet, Camille Guertin, Isabelle Turcotte, Rémi Fromentin, Myriam Maude Verly, Jérémie Prévost, Andrew Clark, Walther Mothes, Daniel E Kaufmann, Frank Maldarelli, Nicolas Chomont, Philippe Bégin, Cécile Tremblay, Jean-Guy Baril, Benoit Trottier, Sylvie Trottier, Ralf Duerr, Marzena Pazgier, Madeleine Durand, Andrés Finzi. DOI 10.1093/infdis/jiad503

Baseline characteristics of a prospective cohort study of aging and cardiovascular diseases among people living with <scp>HIV</scp> HIV Medicine, 2023/12. Katia Giguère, Carl Chartrand‐Lefebvre, Jean‐Guy Baril, Brian Conway, Mohamed El‐Far, Julian Falutz, Marianne Harris, Mohammad-Ali Jenabian, Jonathon Leipsic, Mona Loutfy, Samer Mansour, Paul MacPherson, Shari Margolese, Jacqueline M. McMillan, Ken Monteith, Melanie C. M. Murray, Neora Pick, Réjean Thomas, Benoît Trottier, Sylvie Trottier, Christos Tsoukas, Sharon Walmsley, Alex Wong, Cécile Tremblay, Madeleine Durand, The Canadian HIV And Aging Cohort Study Group. DOI 10.1111/hiv.13550

Vaccine Effectiveness of non-adjuvanted and adjuvanted trivalent inactivated influenza vaccines in the prevention of influenza-related hospitalization in older adults: A pooled analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN) Vaccine, 2023/10. POTT, H, Melissa Andrew, Zachary Shaffelburg, Michaela K. Nichols, Lingyun Ye, May ElSherif, Todd Hatchette, Jason LeBlanc, Ardith Ambrose, Guy Boivin, William Bowie, Jennie Johnstone, Kevin Katz, Phillipe Lagacé-Wiens, Mark Loeb, Anne McCarthy, Allison McGeer, Andre Poirier, Jeff Powis, David Richardson, Makeda Semret, Stephanie Smith, Daniel Smyth, Grant Stiver, Sylvie Trottier, Louis Valiquette, Duncan Webster, Shelly A. McNeil. DOI 10.1016/j.vaccine.2023.08.070

Leveraging Influenza Virus Surveillance From 2012 to 2015 to Characterize the Burden of Respiratory Syncytial Virus Disease in Canadian Adults ≥50 Years of Age Hospitalized With Acute Respiratory Illness Open Forum Infectious Diseases, 2023/07/01. May ElSherif, Melissa Andrew, Lingyun Ye, Ardith Ambrose, Guy Boivin, William Bowie, Marie-Pierre David, Olivier Gruselle, Scott A Halperin, Todd F Hatchette, Jennie Johnstone, Kevin Katz, Joanne M Langley, Mark Loeb, Donna MacKinnon-Cameron, Anne McCarthy, Janet E McElhaney, Allison McGeer, Andre Poirier, Jean-Yves Pirçon, Jeff Powis, David Richardson, Makeda Semret, Stephanie Smith, Daniel Smyth, Sylvie Trottier, Louis Valiquette, Duncan Webster, Shelly A McNeil, Jason J LeBlanc, May ElSherif, Melissa K Andrew, Lingyun Ye, Ardith Ambrose, Guy Boivin, William Bowie, Marie-Pierre David, Olivier Gruselle, Scott A Halperin, Todd F Hatchette, Jennie Johnstone, Kevin Katz, Joanne M Langley, Mark Loeb, Donna MacKinnon-Cameron, Anne McCarthy, Janet E McElhaney, Allison McGeer, Andre Poirier, Jean-Yves Pirçon, Jeff Powis. DOI 10.1093/ofid/ofad315

BEING: Bone Health in Aging Women with HIV: Impact of Switching Antiretroviral Therapy on Bone Mineral Density During the Perimenopausal Period AIDS Research and Human Retroviruses, 2023/04/01. Sharon Walmsley, Rosemarie Clarke, Terry Lee, Joel Singer, Angela M. Cheung, Fiona Smaill, Alexandra De Pokomandy, Sylvia Trottier, Emanuela Messina, Giovanni Guaraldi. DOI 10.1089/aid.2022.0106

Label-Free SERS for Rapid Differentiation of SARS-CoV-2-Induced Serum Metabolic Profiles in Non-Hospitalized Adults Analytical Chemistry, 2023/02/21. Malama Chisanga, Hannah Williams, Denis Boudreau, Joelle Pelletier, Sylvie Trottier, Jean-Francois Masson. DOI 10.1021/acs.analchem.2c04514

Assessment of the longitudinal humoral response in non-hospitalized SARS-CoV-2-positive individuals at decentralized sites: Outcomes and concordance Frontiers in Immunology, 2023/01/20. Abdelhadi Djaïleb, Étienne Lavallée, Megan-Faye Parker, Marie-Pierre Cayer, Florence Desautels, Marie Joëlle de Grandmont, Matthew Stuible, Christian Gervais, Yves Durocher, Sylvie Trottier, Denis Boudreau, Jean-Francois Masson, Danny Brouard, Joelle N. Pelletier. DOI 10.3389/fimmu.2022.1052424

Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286) Patient Preference and Adherence, 2022/12. Marina Klein, Jim Young, David Ortiz-Paredes, Shouao Wang, Sharon Walmsley, Alexander Wong, Valérie Martel-Laferrière, Neora Pick, Brian Conway, Jonathan Angel, Jean-Guy Baril, Chris Fraser, Bertrand Lebouché, Darrell Tan, Roger Sandre, Sylvie Trottier, Hansi Peiris, Jayamarx Jayaraman, Joel Singer. DOI 10.2147/ppa.s379065

Vaginal microbiota associated with oncogenic HPV in a cohort of HPV-vaccinated women living with HIV International Journal of STD & AIDS, 2022/08. Elisabeth McClymont, Arianne Y Albert, Christine Wang, Scott Dos Santos, François Coutlée, Marette Lee, Sharon Walmsley, Nancy Lipsky, Mona Loutfy, Sylvie Trottier, Fiona Smaill, Marina B Klein, Mark H Yudin, Marianne Harris, Wendy Wobeser, Janet E Hill, Deborah M Money, the CTN 236 HPV in HIV Study Team. DOI 10.1177/09564624221109686

Older Age and Frailty are Associated with Higher Mortality but Lower ICU Admission with COVID-19 Canadian Geriatrics Journal, 2022/06/01. Melissa Andrew, Judith Godin, Jason LeBlanc, Guy Boivin, Louis Valiquette, Allison McGeer, Janet E. McElhaney, Todd F. Hatchette, May ElSherif, Donna MacKinnon-Cameron, Kevin Wilson, Ardith Ambrose, Sylvie Trottier, Mark Loeb, Stephanie W. Smith, Kevin Katz, Anne McCarthy, Shelly A. McNeil. DOI 10.5770/cgj.25.546

Recalibrated estimates of non-bacteremic and bacteremic pneumococcal community acquired pneumonia in hospitalized Canadian adults from 2010 to 2017 with addition of an extended spectrum serotype-specific urine antigen detection assay Vaccine, 2022/04. Jason J. LeBlanc, May ElSherif, Lingyun Ye, Donna MacKinnon-Cameron, Ardith Ambrose, Todd F. Hatchette, Amanda L.S. Lang, Hayley D. Gillis, Irene Martin, Walter H.B. Demczuk, Melissa K. Andrew, Guy Boivin, William Bowie, Karen Green, Jennie Johnstone, Mark Loeb, Anne E. McCarthy, Allison McGeer, Makeda Semret, Sylvie Trottier, Louis Valiquette, Duncan Webster, Shelly A. McNeil. DOI 10.1016/j.vaccine.2022.02.081

A Pre–Phase III Efficacy Trial of the Spermicide/Contraceptive Effect of the Invisible Condom, a Non-Hormonal Vaginal Gel, in Women from Canada Journal of Obstetrics and Gynaecology Canada, 2022/02. Rabeea F. Omar, Mathieu Leboeuf, Madeleine Lemyre, Isabelle Chabot, Sylvie Trottier, André Ulmann, Michel G. Bergeron. DOI 10.1016/j.jogc.2021.09.018

Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins Scientific Reports, 2021/11/08. Maryam Hojjat Jodaylami, Abdelhadi Djaïleb, Pierre Ricard, Étienne Lavallée, Stella Cellier-Goetghebeur, Megan-Faye Parker, Julien Coutu, Matthew Stuible, Christian Gervais, Yves Durocher, Florence Desautels, Marie-Pierre Cayer, Marie Joëlle de Grandmont, Samuel Rochette, Danny Brouard, Sylvie Trottier, Denis Boudreau, Joelle N. Pelletier, Jean-Francois Masson. DOI 10.1038/s41598-021-00844-z

Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA Pathogens, 2021/04/27. DOI 10.3390/pathogens10050526

Urinary symptoms and quality of life in women living with HIV: a cross-sectional study International Urogynecology Journal, 2021/02. DOI 10.1007/s00192-020-04343-z

Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV. Pathogens & immunity, 2021/01/14. DOI 10.20411/pai.v6i1.384

Cross-validation of ELISA and a portable surface plasmon resonance instrument for IgG antibody serology with SARS-CoV-2 positive individuals The Analyst, 2021. Abdelhadi Djaileb, Maryam Hojjat Jodaylami, Julien Coutu, Pierre Ricard, Mathieu Lamarre, Léa Rochet, Stella Cellier-Goetghebeur, Devin Macaulay, Benjamin Charron, Étienne Lavallée, Vincent Thibault, Keisean A.J.M. Stevenson, Simon Forest, Ludovic S. Live, Nanouk Abonnenc, Anthony Guedon, Patrik Quessy, Jean-François Lemay, Omar Farnós, Amine Kamen, Matthew Stuible, Christian Gervais, Yves Durocher, François Cholette, Christine Mesa, John Kim, Marie-Pierre Cayer, Marie-Joëlle de Grandmont, Danny Brouard, Sylvie Trottier, Denis Boudreau, Joelle N. Pelletier, Jean-Francois Masson. DOI 10.1039/d1an00893e

Prevalent and persistent oncogenic HPV types in a cohort of women living with HIV prior to HPV vaccination International Journal of Gynecology & Obstetrics, 2020/07. DOI 10.1002/ijgo.13185

Predictors of Clostridioides difficile Infection Among Asymptomatic, Colonized Patients: A Retrospective Cohort Study Clinical Infectious Diseases, 2020/05/06. DOI 10.1093/cid/ciz626

Impact of quadrivalent HPV vaccine dose spacing on immunologic response in women living with HIV Vaccine, 2020/03. DOI 10.1016/j.vaccine.2020.02.075

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015 BMJ Open Respiratory Research, 2020/03. DOI 10.1136/bmjresp-2019-000550

Brief Report: Persistence of Non-Vaccine Oncogenic HPV Genotypes in Quadrivalent HPV-Vaccinated Women Living With HIV JAIDS Journal of Acquired Immune Deficiency Syndromes, 2020/03/01. DOI 10.1097/qai.0000000000002258

Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults Journal of Medical Microbiology, 2020/02/01. DOI 10.1099/jmm.0.001032

Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs JAIDS Journal of Acquired Immune Deficiency Syndromes, 2019/12/15. DOI 10.1097/qai.0000000000002185

The Impact of Prior Season Vaccination on Subsequent Influenza Vaccine Effectiveness to Prevent Influenza-related Hospitalizations Over 4 Influenza Seasons in Canada Clinical Infectious Diseases, 2019/08/30. DOI 10.1093/cid/ciy1009

Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network (CIRN) Vaccine, 2019/08. DOI 10.1016/j.vaccine.2019.05.003

The Efficacy of the Quadrivalent Human Papillomavirus Vaccine in Girls and Women Living With Human Immunodeficiency Virus Clinical Infectious Diseases, 2019/02/15. DOI 10.1093/cid/ciy575

Effect of valaciclovir on CD4 count decline in untreated HIV: an international randomized controlled trial Journal of Antimicrobial Chemotherapy, 2019/02/01. Darrell H S Tan, Janet M Raboud, Leah Szadkowski, Beatriz Grinsztejn, José Valdez Madruga, Maria Ines Figueroa, Pedro Cahn, Simon E Barton, Amanda Clarke, Julie Fox, Wendy Zubyk, Sharon L Walmsley, Jason Brunetta, William Cameron, Jeff Cohen, Brian Conway, Claude Fortin, Chris Fraser, Don Kilby, Marina Klein, Ken Logue, Neora Pick, Anita Rachlis, Barbara Romanowski, Fiona Smaill, Sylvie Trottier, Alan Winston, the VALIDATE Study Group. DOI 10.1093/jac/dky433

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD Chest, 2019/01. DOI 10.1016/j.chest.2018.10.044